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Pharmacology II

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Praxis Tests: Pharmacology Quiz on Pharmacology II, created by ACAPUN INSTITUTE on 09/11/2021.
ACAPUN INSTITUTE
Quiz by ACAPUN INSTITUTE, updated more than 1 year ago
ACAPUN INSTITUTE
Created by ACAPUN INSTITUTE about 3 years ago
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Resource summary

Question 1

Question
Diazepam is preferred to a barbiturate as an antianxiety agent because diazepam
Answer
  • a. Produces no sedation
  • b. Has less addiction potential
  • c. Is a very short-acting drug
  • d. Is substantially less expensive
  • e. Does not potentiate the action of CNS depressants

Question 2

Question
Diazepam is preferred to a barbiturate as an antianxiety agent because diazepam
Answer
  • a. Produces no sedation
  • b. Has less addiction potential
  • c. Is a very short-acting drug
  • d. Is substantially less expensive
  • e. Does not potentiate the action of CNS depressants

Question 3

Question
Benzodiazepines exert their main effect on
Answer
  • a. Neuromuscular junctions
  • b. Peripheral reflex synapses
  • c. Central GABAergic neurons
  • d. Central serotonergic neurons
  • e. Central adrenergic nerve endings

Question 4

Question
All of the following pertain to general anesthesia induced by thiopental EXCEPT:
Answer
  • a. Fast induction
  • b. Decreased secretions
  • c. Low therapeutic index
  • d. Short duration of anesthesia
  • e. Predisposition to laryngospasm

Question 5

Question
Which of the following factors contributes to the short duration of action of a single dose of thiopental?
Answer
  • a. rapid biotransformation
  • b. rapid accumulation in body fat
  • c. high lipid solubility of the undissociated form
  • d. ability to enter and leave the brain tissue rapidly

Question 6

Question
Speed of recovery from short-acting anesthesia with thiopental depends chiefly on the rapidity of
Answer
  • a. Renal tubular secretion
  • b. Hepatic degradation of the thiopental group
  • c. Redistribution from the brain to skeletal muscle
  • d. Reverse diffusion across the blood-brain barrier
  • e. None of the above

Question 7

Question
The action of the ultrashort-acting barbiturates is terminated primarily by the process of
Answer
  • a. Oxidation
  • b. Redistribution
  • c. Renal excretion
  • d. Plasma protein binding
  • e. Conjugation with sulfate

Question 8

Question
Which of the following is NOT characteristic of barbiturates?
Answer
  • a. Possess anticonvulsant properties
  • b. Possess significant analgesic properties
  • c. Possess serious drug dependence potential
  • d. Vary in degree of lipid solubility and hypnotic potency

Question 9

Question
The cause of death from acute barbiturate poisoning is
Answer
  • a. Convulsions
  • b. Liver damage
  • c. Renal failure
  • d. Respiratory failure
  • e. Cardiovascular depression

Question 10

Question
Which of the following adverse effects is most commonly associated with administration of an intravenous barbiturate?
Answer
  • a. Hypotension
  • b. Renal failure
  • c. Hepatic necrosis
  • d. Nausea and vomiting
  • e. Respiratory depression

Question 11

Question
Important steps in the treatment of barbiturate poisoning include: a. Maintaining an open airway b. Increasing the input of afferent stimuli c. Maintaining respiration d. Administering a narcotic antagonist e. Administering a central nervous system stimulant
Answer
  • a) (a) and (b) only
  • b) (a), (b), (c) and (e)
  • c) (a) and (c) only
  • d) (b) and (e) only
  • e) (d) only

Question 12

Question
Which of the following are true regarding barbiturates? a. Significantly elevates pain thresholds b. Are metabolized by the liver c. Are classified according to duration of action d. Depress all levels of the CNS e. Cause death by cardiovascular depression
Answer
  • a) (a), (b) and (c)
  • b) (a) and (d)
  • c) (b), (c) and (d)
  • d) (b) and (e)
  • e) (c), (d) and (e)

Question 13

Question
Barbiturates are contraindicated in a dental patient with: a. Emphysema b. Hypertension c. Undiagnosed severe pain d. Acute intermittent porphyria
Answer
  • a) (a), (c) and (d)
  • b) (a) and (d) only
  • c) (b) and (c)
  • d) (b) only

Question 14

Question
If diazepam (Valium) is to be given intravenously, it is recommended that a large vein be used in order to
Answer
  • a. Hasten the onset of action
  • b. Decrease the risk of thrombophlebitis
  • c. Offset the vasoconstrictor qualities of diazepam
  • d. None of the above

Question 15

Question
The most important therapeutic measure to be taken in a case of barbiturate poisoning is to
Answer
  • a. Alkalinize the urine
  • b. Aspirate stomach contents
  • c. Administer a CNS stimulant
  • d. Assure adequate respiration
  • e. Administer osmotic diuretics

Question 16

Question
For oral sedation in the dental setting, the most ideal group of agents is:
Answer
  • a. Narcotics
  • b. Barbiturates
  • c. Antihistamines
  • d. Benzodiazepines
  • e. Anticholinergics

Question 17

Question
Which of the following is an advantage of midazolam over diazepam EXCEPT one. Which one is this EXCEPTION?
Answer
  • a. Lesser incidence of thrombophlebitis
  • b. Shorter elimination half-life
  • c. No significant active metabolites
  • d. Less potential for respiratory depression
  • e. More rapid and predictable onset of action when given intramuscularly

Question 18

Question
Which of the following drugs best reverses the effects of benzodiazepines?
Answer
  • a. Naloxone
  • b. Flumazenil
  • c. Midazolam
  • d. Aminophylline
  • e. Physostigmine
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