Post-Transcription Activation By CAMP

Flussdiagrammknoten

• A Signalling molecule binds to receptor on the plasma membrane of target cell

• This activates the G protein.

• The G Protein activates Adenyl cyclase enzymes

• Activated Adenyl Cyclase enzymes catalyse formation of cAMP from ATP

• cAMP activates PKA (protein kinase A)

• PKA catalyses the phosphorylation of many other enzymes, hydrolysing ATP in the process 

• Glycogen becomes converted into glucose

• May phosphorylate other proteins

• This then enters the nucleus and acts as a transcription factor to regulate transcription