13194864
Signal Transduction
- STARTS with chemical
message which is
transduced into specific
forms and sent out
- Analogy: Jimi Hendrix playing
guitar; vibrations he plays on
strings is transduced by magnets
into an electric signal
- Analogy: Jimi Hendrix playing
guitar; vibrations he plays on
strings is transduced by magnets
into an electric signal
- Receptors pick up
message and modify it
- Types of receptors: G
couple protein receptors,
Tyrosine KINASE receptors,
ligand gated ion channel
- then sent to
transduction where
the message is made
in a specific form
(secondary
messenger) for the
target cell
- ex. cAMP
- ex. cAMP
- Types of receptors: G
couple protein receptors,
Tyrosine KINASE receptors,
ligand gated ion channel
- EX. Epinephrine (ligand) binds with
G-protein (receptor); change in shape
of protein and subunit is released to
Adenylyl Cyclase (protein) which
activates adenylyl - converts ATP in
cAMP (secondary messenger); cAMP is
spread through out the cell targeting
protein kinase; extras able to bond
with other proteins in cell such as
phosphate which phosphorilizes to
produce glucose
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