AGING

Beschreibung

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melanie ciel
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melanie ciel
Erstellt von melanie ciel vor etwa 6 Jahre
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Zusammenfassung der Ressource

AGING
  1. DEFINITION
    1. HALLMARKS OF AGING
      1. telomerase overexpression and shelterin mutation
        1. LOSS OF PROTEOSTASIS:
          1. DEREGULATED NUTRIENT SENSING
            1. MITOCHONDRIAL DYSFUNCTION
              1. TELOMRERE ATTRITION
                1. EPIGENETUIC ALTERATIONS
                  1. GENOMIC INSTABILITY
                    1. DAMAGE
                      1. NUCLEAR DNA
                          1. MT DNA
                            1. GENOMIC
                        1. CELLULAR SENESCENCE
                          1. STEM CELL EXHAUSTION
                            1. ALTERED INTRACELLULAR COMMUNICATION
                            2. THE PROGRESSIVE LOSS OF PHYSOLOGICAL INTEGRITY LEADING TO IMPIARED FUNCTION
                            3. THEORIES OF AGING
                              1. PROGRAMMED THEORIES
                                1. PROGRAMMED SENECENESE
                                  1. ENDOCRINE
                                    1. IMMOUNOLOGY
                                    2. ERROR THEORY
                                      1. WEAR AND TEAR
                                        1. RATE OF LIVING
                                          1. CROSS LINKING
                                            1. FREE RADICALS
                                              1. ERROR CATASTROPHE
                                              2. GENETIC
                                                1. MITOCHONDRIAL
                                                  1. CALORIE RESTRECTION
                                                    1. TELOMERE
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