Zusammenfassung der Ressource
Losing weight
- Anatomy of the thyroid
- Thyroid hormone
- TSH
- upregulates activity of iodide pump
- Endocytosis of iodinated thyroglobulin
- Upregulates TPO and thyroglobulin
- thyroid follicles cells
- Thyroxine (T4)
- Tri-iodothyronine (T3)
- Reverse,rT3
- parafollicular cells
- Calcitonin
- Hyperthroidism
- Causes
- 2-Functioning adenoma and toxic multinodular goiter
- Excessive intake of thyroid hormones
- Abnormal secretion of TSH
- Graves Disease
- B-cell production of IgG antibodies
- Mutations in HLA-DR3 & HLA-B8
- Exophthalmos
- Pretibial Myxedema
- Thyroid Acropathy
- Signs and Symptoms
- Nervousness and irritability
- Increased resting heart rate
- Heat intolerance
- Tremors
- Weight loss
- Frequent bowel movements
- Management
- antithyroid drugs
- radioactive iodine
- surgical removal
- Adjunctive therapy
- Beta blockers
- Iodine
- Steroids
- Adverse effects
- agranulocytosis
- congenital goiter
- Skin rash
- neutropenia
- Goiter
- Hoarseness
- Difficulty swallowing
- Difficulty breathing
- Risk Factors
- A lack of dietary iodine
- female
- autoimmune disease
- Radiation exposure