Zusammenfassung der Ressource
Enzyme Inhibitors
- Inhibitors: substances that reduce the
reaction rate in an enzyme controlled
reaction because they have some effect
on the enzyme
- Competitive inhibitors have a
similar shape to the substrate
- They can occupy the active
site forming enzyme
inhibitor complexes
- Enzyme inhibition occurs whenever a inhibitor
molecule is occupying an enzymes active site,
a substrate molecule cannot enter so the rate
of reaction slows down
- Non-competitive inhibitors don't
compete for a place in the active site
- they attach to the enzyme molecule in a
region away from the active site
- this attachment distorts the 3D structure, this leads to a
change in shape of the active site
- this means the substrate no longer fits, so e/s complexes
can't form and the rate of reaction decreases