Anemia caused by ↑ RBC destruction or loss

Beschreibung

Mindmap am Anemia caused by ↑ RBC destruction or loss, erstellt von Sarah Phillips am 11/04/2015.
Sarah Phillips
Mindmap von Sarah Phillips, aktualisiert more than 1 year ago
Sarah Phillips
Erstellt von Sarah Phillips vor mehr als 9 Jahre
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Zusammenfassung der Ressource

Anemia caused by ↑ RBC destruction or loss
  1. Intrinsic Abn
    1. Membrane Defect
      1. hereditary spheocytosis
        1. hereditary elliptocytosis
          1. pyropoikilocytosis (subset of HE)
          2. paroxysmal nocturnal hemoglobinuria
            1. hereditary stomatocytosis
              1. hereditary xerocytosis
              2. Enzyme Deficiency
                1. G6PD
                  1. pyruvate kinase
                  2. Qualitative Globin Abn
                    1. Single Amino Acid Substitutions Usually in Beta Chain
                      1. Sickle cell anemia/trait
                        1. Hgb S: anemia; Hgb SA: trait
                        2. Hgb C Dx
                          1. Hgb AC
                            1. Hgb SC
                            2. Variant Hgbs
                              1. Hgb S-beta thal
                                1. Hgb E
                                  1. Hgb D
                                    1. Hgb Lepore (delta - beta fusion)
                              2. Extrinsic Abn
                                1. Immune Causes (Ab mediated)
                                  1. Warm autoimmune hem anemia
                                    1. Cold agglutinin Dx
                                      1. Paroxysmal Cold Hemoglobinuria
                                        1. HTR & HDFN
                                          1. Immune Thrombocytopenia
                                          2. Non Immune (not Ab mediated) RBC Injury
                                            1. Microangiopathic hemolytic anemia
                                              1. Thrombotic thrombocytic anemia
                                                1. HELLP syndrome
                                                  1. DIC
                                                    1. HUS
                                                    2. Macroangiopathic hemolytic anemia
                                                      1. traumatic cardiac hemolysis
                                                      2. Infectious agents
                                                        1. malaria
                                                          1. babesiosis
                                                            1. bartonellosis
                                                              1. clostridial sepsis
                                                              2. Other injury
                                                                1. chemicals
                                                                  1. drugs
                                                                    1. burns
                                                                      1. venoms
                                                                      2. Non Megaloblastic Macrocytic Anemia
                                                                        1. RBC destruction from underlying condition: BM compensates
                                                                          1. hypothyroidism
                                                                            1. chronic liver dx
                                                                              1. alcoholism
                                                                                1. chemo
                                                                                  1. post splenectomy
                                                                              2. Acute Blood Loss
                                                                              3. ↑ Retic
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