Sickle Cell Anemia

Beschreibung

(Biology Exam 2) Mindmap am Sickle Cell Anemia, erstellt von izzy5605 am 22/10/2013.
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Mindmap von izzy5605, aktualisiert more than 1 year ago
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Zusammenfassung der Ressource

Sickle Cell Anemia
  1. change in one nucleotide
    1. changes entire amino acid sequence
      1. changes structure of protein
        1. changes shape of red blood cell (sickle shape)
          1. protein misfolding
            1. some hydrophobic amino acids could be displayed on surface
              1. changes cell function
      2. inherited
        1. protein aggregation
          1. because of misfolding they clump together
          2. malaria
            1. one sickle cell mutation and one non mutated gene
              1. resistant to malaria
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