Zusammenfassung der Ressource
Inflamation
- Vascular
Phase
- Immediate short moment of vasoconstriction
- Vasodialation of arterioles and venules
- Increased vascular permeablity
- protein rich exudate into extravascular space
- reduction in capillary osmotic
pressure
- Increase interstitial osmotic
presure
- swelling, pain and loss off function
- Increased capillary blood flow
- Increased heat and redness
- Cellular
Phase
- Delivery of leukocytes to damaged tissue area via arteriole
(majority being neutorphils)
- Migration to site
- Adhesion to capillary wall
- Transmigration into interstitial fluid
- Arrival to damaged cells
- Accomplished through chemotaxis
- movement as a result of chemical gradients
- Leukocyte activation
- Chemicals produced by injured cells activate
phyagocytosis of injured cell
- Caused by complementary adhesion molecules
- Cell Damage