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Beschreibung
Mindmap von Jasper McClellan, aktualisiert more than 1 year ago
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Erstellt von Jasper McClellan
vor mehr als 2 Jahre
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Exam 2: Biguanides
- Nursing Interventions
- Monitor LFTs, BUN, and Cr before starting
- Continue yearly monitoring
- Continue yearly monitoring
- Monitor LFTs, BUN, and Cr before starting
- Pharmacokinetics
- Not metabolized; excreted unchanged in urine
- Not metabolized; excreted unchanged in urine
- Adverse effects
- Lactic acidosis
- Metallic taste in the mouth
- Dehydration
- Decreased absorption of B12 and folic acid
- Weight loss
- Lactic acidosis
- Contraindications
- Lactic Acid concern:
- Alcoholism
- Hepatic and renal impairment
- Shock
- Severe infection
- Dehydration
- Alcoholism
- Lactic Acid concern:
- Drug interactions
- Can cause lactic acidosis
- Contrast dyes
- Stop taking 1-2 days before
- Monitor BUN and Cr
- Stop taking 1-2 days before
- Cimetidine
- Contrast dyes
- Hypoglycemics
- Can cause lactic acidosis
- Pharmacological action
- Increases sensitivity of insulin receptions
- Decreases absorption
of glucose from the
intestines
- Decreases synthesis of
glucose by the liver
- Increases sensitivity of insulin receptions
- Other information
- Advantages
- Safe for pregnancy
- No weight gain
- No hypoglycemia
- Safe for pregnancy
- Advantages
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