Zusammenfassung der Ressource
Hereditary WBC Disorders
- May-Hegglin Anomaly
- Associated Conditions
Anmerkungen:
- Abnormal bleeding may be present in some individuals.
- thrombocytopenia
- giant platelets
- WBC's affected
- neutrophils
- appearance
- Döhle-like bodies
Anmerkungen:
- Rod shaped inclusions at the edge of the cytoplasm. They are like Döhle bodies but larger.
- prevalence
- unknown
- Alder-Reilly Anomaly
- Associated Conditions
- dwarfism
- gargoylism
- WBC's affected
- All cell lines
- hallmark feature
- Appearance
- coarse dark granulation
- prevalence
- rare
- Pelger-Huet Anomaly
- prevalence
- common
- associated conditions
- leukemias
- myleoproliferative disorders
- severe infections
- WBC's affected
- segmented neutrophils
- appearance
- hyposegmentation of nucleus
- heterozygotes
- peanut-shaped
- dumbbell-shaped
- pince-nez-shaped
- homozygotes
- spherical non-lobed
- Chediak-Higashi Syndrome
- prevalence
- rare
- associated conditions
- neutropenia
- albinism
- photophobia
- recurrent staphylococcus infections
- WBC's affected
- neutrophils (mostly)
- lymphocytes
- monocytes
- appearance
- giant purple-gray granules