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Hereditary WBC Disorders

Beschreibung

Mindmap am Hereditary WBC Disorders, erstellt von KevinShirley am 20/11/2013.
KevinShirley
Mindmap von KevinShirley, aktualisiert more than 1 year ago
KevinShirley
Erstellt von KevinShirley vor etwa 12 Jahre
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Zusammenfassung der Ressource

Hereditary WBC Disorders
  1. May-Hegglin Anomaly
    1. Associated Conditions

      Anmerkungen:

      • Abnormal bleeding may be present in some individuals.
      1. thrombocytopenia
        1. giant platelets
        2. WBC's affected
          1. neutrophils
          2. appearance
            1. Döhle-like bodies

              Anmerkungen:

              • Rod shaped inclusions at the edge of the cytoplasm. They are like Döhle bodies but larger.
            2. prevalence
              1. unknown
            3. Alder-Reilly Anomaly
              1. Associated Conditions
                1. dwarfism
                  1. gargoylism
                  2. WBC's affected
                    1. All cell lines
                      1. hallmark feature
                    2. Appearance
                      1. coarse dark granulation
                      2. prevalence
                        1. rare
                      3. Pelger-Huet Anomaly
                        1. prevalence
                          1. common
                          2. associated conditions
                            1. leukemias
                              1. myleoproliferative disorders
                                1. severe infections
                                2. WBC's affected
                                  1. segmented neutrophils
                                  2. appearance
                                    1. hyposegmentation of nucleus
                                      1. heterozygotes
                                        1. peanut-shaped
                                          1. dumbbell-shaped
                                            1. pince-nez-shaped
                                            2. homozygotes
                                              1. spherical non-lobed
                                        2. Chediak-Higashi Syndrome
                                          1. prevalence
                                            1. rare
                                            2. associated conditions
                                              1. neutropenia
                                                1. albinism
                                                  1. photophobia
                                                    1. recurrent staphylococcus infections
                                                    2. WBC's affected
                                                      1. neutrophils (mostly)
                                                        1. lymphocytes
                                                          1. monocytes
                                                          2. appearance
                                                            1. giant purple-gray granules

                                                          Medienanhänge

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