Zusammenfassung der Ressource
What is the role of eEF1A1 during heat shock response?
- What processes is eEF1A1 a part of in HSR?
- Is it involved in translation?
- What elements of translation is it
involved with?
- eEF1A1 facilitates HSP70
mRNA nuclear export
- eEF1A1 binds to 3'UTR of
HSP70 and regulates its
stability
- Is it involved in transcription?
- What elements of transcription is it
involved with?
- What happens in
transcription when
eEF1A1 is knocked
down?
- Is there a function of the cell
or a protein that is reduced
as a result of knocking down
eEF1A1
- How does eEF1A1
regulate HSP70
expression?
- How does eEF1A1 regulate thermotolerance?
- Does the other isofrom
of eEF1A (eEF1A2) have
the same affect if it is
knocked down?
- What is the mechanism in
which eEF1A1 regulates
transcription of HSP genes?
- eEF1A1 mediates
HSF1 recruitment
to HSP70 promoter
- eEF1A1 localizes at HSP70
and interacts with RNAIIP
during HS