Zusammenfassung der Ressource
Autoimmune disease
- immune response against one or more self-antigen
- autoantigens
- autoimmuneresponse
- how it happens ?
- complement - mediated lysis
- opsonisation
- inhibition of receptor function
- stimulation of receptors
- blockage of biological function
- deposition of immune complexes
- causes of AD
- genetic - polygenic factors
- environmental
- loss of immunetolerance