Cell Signaling

Cell Signaling

Cell Surface Receptor Proteins
1. Enzyme Coupled Receptor
2. G-Protein Coupled Receptor
3. Intracellular Signaling Molecules
  1. Small Chemicals
    1. cAMP
    2. Ca2+
    3. "2nd Messengers"
  2. Proteins
    1. Molecular Switches
      1. Phosphorylation/Dephosphorylation
        Tyrosine Kinases
        "Kinase Cascades"
        Serine/Threonine Kinases
      2. GTP/GDP binding
        GAPs+GEFs
        Trimeric G-Proteins
        Monomeric GTPases
    2. Generate 2nd Messengers
    3. Caspases
4. Ion-Channel Coupled Receptor
  1. Nerve Cells
Types of Signal Molecules
1. Proteins
2. Neurotransmitters
3. Gases
4. Fatty Acids
Signaling Characteristics
1. Scaffolding Proteins
2. Differences in Responses
Distance
1. Long Distance
  1. Endocrine
  2. Synaptic
2. Short Distance
  1. Autocrine
  2. Paracrine
  3. Contact Dependent

Zusammenfassung der Ressource

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