bone tumours

Beschreibung

Paediatrics (Malignancy) Mindmap am bone tumours, erstellt von v.djabatey am 31/01/2014.
v.djabatey
Mindmap von v.djabatey, aktualisiert more than 1 year ago
v.djabatey
Erstellt von v.djabatey vor fast 11 Jahre
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Zusammenfassung der Ressource

bone tumours
  1. malignant bone tumours uncommon before puberty
    1. male>female
      1. osteogenic sarcoma
        1. more common
        2. Ewing sarcoma
          1. seen more freq in younger kids
        3. clinical features
          1. limbs commonest site
            1. characteristic sx
              1. persistent localised bone pain
                1. indication for early x-ray
                  1. precedes detection of a mass
                2. pts otherwise well @ diag
                3. Ix
                  1. 1st plain Xray
                    1. then MRI & bone scan
                      1. shows destruction & variable periosteal new bone formation
                        1. substantial soft tissue mass
                          1. in Ewing sarcoma
                        2. chest CT
                          1. to assess for lung mets
                          2. bone marrow sampling
                            1. exclude marrow involvement
                          3. Mx
                            1. in both tumours
                              1. combo chemo
                                1. then surgery
                                  1. amputation avoided where possible
                                    1. using en bloc resection of tumours w/ endoprosthetic resection
                              2. Ewing sarcoma
                                1. radiotherapy also used
                                  1. manage local disease, esp when surgical resection impossible/incomplete e.g. in pelvis, axial skeleton
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