Zusammenfassung der Ressource
Innate Immune Response
- non-specific
- immune
components
preformed
- response magnitude
- similar during 1st and subsequent encounters
- No memory is stored
- 1st lines of Defence
- Physical barrier
- saliva
- antibacterial enzyme
- mucus linings
- traps dirt and microbes
- Chemical barrier
- skin
- prevent entry of phatogents
- tears
- antibacterial enzyme
- "good" gut bacteria
- stop other harmful bacteria that taking over
- 2nd lines of defence
- fever
- increase temperature above 37
- change settings of hypothalamus
- initiated by pyrogens
- benefits
- reduced iron availability
- Inhibition of microbial multiplication
- increase metabolic reactions
- inflammation
- redness
- heat
- pain
- oedema
- stages of inflammation
- tissue injury
- release of chemical signals such as histamine
- dilation and increased leakiness of local blood vessels
- migration of phagocytes to the area
- phagocytes
- tissue heals
- release of cytokines
- vasodilation
- phagocytosis
- macrophages
- neutrophils
- posses lysosome
- Antimicrobial proteins
- complement system
- interferons
- iron-binding protein
- Antimicrobial peptides