Zusammenfassung der Ressource
B1.3 The use and abuse of drugs
- Drugs
- Extensively tested and trialled
- Tested in the lab
- 1st stage: cells, tissues
- 2nd stage: live animals
- Clinical trials
- 3rd stage: healthy volunteers
- Low dosage at start
- Slowly increased
- Test for side effects
- 4th stage: patients with the illness
- Optimum dosage found
- Least side effects
- 5th stage: blind clinical trials- patients split into two groups
- One group given the real drug,
another given a placebo
- Allows for placebo effect
- Patient expects drug to work so
feels better, even if the 'drug' is
doing nothing
- Placebo
- Substance like the drug being
tested but doesn't do anything
- Sometimes trials are double blind
- Patient nor doctor knows which is the placebo
- For toxicity, efficacy and dose
- Thalidomide
- Intended as a sleeping pill
- Found effective against morning sickness
- Has not been tested on pregnant women
- Many babies born with severe limb abnormalities
- Drug banned
- Resulted in more
rigorous drug
testing
- Now used to treat other diseases
- Leprosy
- Legal and illegal drugs
- Medicinal
- Some require prescription
- Morphine
- Some do not
- Paracetamol
- Statins
- Lower risk of heart and circulatory diseases
- Also lower blood cholesterol
- And risk of heart disease in diabetic patients
- Recreational
- Used for fun
- Legal
- Alcohol
- Slows
reactions
- Liver disease
- Brain damage
- Nicotine
- Cancer
- Addiction
- Disease of
heart and
lungs
- Illegal
- Ecstasy
- Cannabis
- Can cause mental health problems
- Considered a gateway drug
- Heroin
- All three can cause
heart and circulatory
problems
- Addictive
- Performance enhancing
- Improve an athlete's
performance in sport
- Anabolic steroids
- Increase muscle size
- Can lead to
high blood
pressure
- Stimulants
- Increase heart rate
- Arguments against
- Unfair
- Athletes may not have been
informed about the risks
- Arguments for
- Athletes can make their own decisions
- Sport is not fair anyway,
different training facilities etc
- Some illegal, some prescribed
- All banned from sporting bodies
- The overall impact of legal drugs is
- Much greater than the impact of illegal drugs
- More people use them
- Have negative effects on economy and society
- Effects of drugs
- Change body chemistry
- Results in
- Becoming addicted
- If addicts do not take the drug they have
- Withdrawal symptoms