Zusammenfassung der Ressource
Pediatric Asthma
- Pathophysiology
- Antigen exposure to
bronchial mucosa
- IgE produced
- Degranulation of
mast cells
- Inflammatory mediators released
- Vasodilation
- Capillary permeability
- Mucosal edema
- Increased CO2 retention
- Increased pH
- Decreased PaCO2
- Hypoxemia
- Hyperventilation
- Air trapping
- Hyperinflation
- Increased
intrapleural/alveolar
gas pressure
- Treatment
- Oxygen
- Immunotherapy
- Removal of allergen/irritant
- Inhaled beta-agonist bronchodilators
- Oral corticosteroids
- Antibiotics
(bacterial)
- Risk Factors
- Genetics
- Boys
- Allergies
- Black/Hispanic
- Live in urban setting
- Low
socioeconomic
status
- Air pollution
- Insects (cockroaches)
- Recent viral/upper
respiratory infection
- Diagnosis
- PFT with spirometry
- Empirical trial of asthma meds
- Asthma
Predictive
Index (API)
- Pulse oximetry
- Parental
history of
asthma/atopic
dermatitis
- Clinical Manifestations
- Coughing
- Expiratory
wheezing
- Short
of
breath
- Increased heart and
respiratory rate
- Nasal
flaring
- Head
bobbing
- Anxious
- Diaphoretic
- Exercise
intolerance
- Using
accessory
muscles
- Hyperinflation