Zusammenfassung der Ressource
Colorectal carcinoma
- polyps
- <1% chance of malignant transformation
- inherited polyposis
- familial adenomatous polyposis FAP
- Gardener's syndrome
- aka familial colorectal polyposis
- AD
- Turcot's syndrome
- rarediseases.info!
- polyps->colorectal ca
- brain tumours
- Peutz-Jeghers (AD)
- polyps and pigmentation
- Cowden's disease
- multiple hamartoma syndrome
- skin 100%
- thyroid 60%
- ca
- GIT
- ca
- breast ca
- others
- familial juvenile polyposis
- hyperplastic polyposis
- common
- colonic polypectomy
- hyperplastic 90%
- adenomas 10%
- tubular
- tubulovillous
- villous
- imaging
- CT colon
- colonoscopy
- common
- rectosigmoid 60%
- risk factors
- history of adenoma
- FH of adenoma
- IBD
- pelvic irradiation
- low fibre, high fat diets
- asbestos
- hereditary non-polyposis
colorectal cancer syndrome
(Lynch syndrome)
- +ve FH
- Lynch I
- Lynch II ass. with GU tract TCC
- Dukes staging
- A: mucosa 85% 5 yr survival
- B: muscularis 70% 5 yr survival
- C: LN 30% 5yr survival
- D: distant mets 5% 5yr survival
- liver
- lung
- adrenals
- ovary
- bone
- brain
- peritoneum