Carcinoid

Carcinoid

primary malignancy
1. small bowel 30%
  1. ileum 80%
    1. single or multiple
    2. may cause ulceration
    3. fibrosis may cause hairpin turn
    4. enhance with Gad
  2. duodenal 2%
    1. well defined, rounded mass
    2. arterial enhancement
    3. portal venous washout
2. appendix 45%
3. stomach 10%
  1. flocculation of contrast
  2. fundus
  3. mets in >60% at diagnosis
4. 30% have a second GI tract primary malignancy
histology
1. neuroendocine cells of submucosa
  1. 5-HIAA
  2. ACTH
  3. histamine
  4. serotonin
mets
1. liver
2. bone
3. lung
4. LN
imaging
1. nuclear med
  1. In-111 octreotide scan
    1. somatostatin +ve carcinoid disease
      1. radiolabelled therapeutic option

Resource summary

	Created by sherry_zaman almost 11 years ago