Zusammenfassung der Ressource
Fatty Acid Metabolism
- Fatty acid degradation
- Occurs via oxidation
- 1. Oxidation at the aB bond to a 2x bond
- 2. Hydration of the aB double bond, with -OH added to the Beta Carbon
- 3. Oxidation of the B hydroxyl group to a ketone/carbonyl
- 4. Cleavage at the alpha carbon between two carbonyls via thiolysis.
- Fatty acid synthesis
- 1. Condensation of the malonyl CoA and acetyl CoA
- 2. Reduction of the Beta ketone closest to the alkyl chain