Frage 1
Frage
The reaction of antibody with a non soluble antigen or an antigen-cated particles result in formation of visible to the eye clumb is called
Antworten
-
agglutination
-
precipitation
-
neutralization
-
complement fixation test
Frage 2
Frage
ELlSA makes use of:
Frage 3
Frage
widal from used to.....
Antworten
-
slide agglutination test
-
tube agglutination
-
CUT
-
lectin pathway
Frage 4
Frage
Which of the following immunoglobulins may be transferes to the fetus during pregnancy
Frage 5
Frage
The genus specific name for group A streptococci is
Antworten
-
streptococcus pneumonia
-
streptococcus viridans
-
streptococcus diphtheria
-
streptococcus pyogenes
Frage 6
Frage
The main pathogenic factor of corynebacterium diphtheria is
Antworten
-
an endotoxin
-
an exotoxin
-
a spore
-
a protein
Frage 7
Frage
The specific prophylaxis of diphtheria is performed by
Frage 8
Frage
Which of the following statement concerning cholera infection is correct?
Antworten
-
death occurs in 46 weeks exclusion and respiratory failure
-
the disease is marked by microorganism invasion and hemorrhage of large intestine
-
vibrio cholera produce an acute fehrile disease with
-
the disease is rapidly progressive and maybe fatal in 2 days because of bacterial multiplication in the gut and shock
Frage 9
Frage
Beta lactamase production is a major problem for treatment of infections caused by:
Frage 10
Frage
HIV has been shown to be transmitted by one of the following except
Antworten
-
Sexual contact
-
Perinatal infection
-
Mosquitos
-
Blood transfer
Frage 11
Frage
Each organism is identified by two names including:
Antworten
-
family and kingdom
-
genus and species
-
family and species
-
family and genus
Frage 12
Frage
[blank_start]Simple[blank_end] techniques of staining make use of only one dye,where as [blank_start]Complex[blank_end] staining a combination of dyes?
Frage 13
Frage
The volutine granules of corynebacterium diptheria are visualized by [blank_start]Neisser[blank_end] Staining
Frage 14
Frage
The following structure are located in the cytoplasmic membrane?
Antworten
-
spore
-
nucleotid
-
ribosomes
-
capsule
Frage 15
Frage
Based on their cell wall structure bacteria are divided into:
Antworten
-
gram(+) and gram(-)
-
aerobe and anerobe
-
sphere and spinal
-
cocci and rods
Frage 16
Frage
Peptidoglycan polymers are found only in:
Antworten
-
bacterial cell
-
animal cell
-
a,b
-
viruses
Frage 17
Frage
Flagella are present in every bacterium
Frage 18
Frage
Sporulation appears to be
Antworten
-
an initiation of the bacterium cell
-
a reaction to conditions that are unfavorable for normal growth
-
a status to resist desiccation and other harmful conditions
-
a,b
-
b,c
Frage 19
Frage
The complete killing or removal of all microorganisms including bacterial spores is called?
Antworten
-
sterilization
-
disinfection
-
antisepsis
-
non is true
Frage 20
Frage
Cytoplasm contains:
Antworten
-
storage granules
-
spores
-
capsules
Frage 21
Frage
Which of following component are not found in the gram negative cell wall?
Antworten
-
amino acids
-
lipopolysaccharides
-
peptidoglycan
-
teichoic acids
Frage 22
Frage
Pfeiffer technique of staining makes use of following dye?
Antworten
-
methylene blue
-
ziehl’s fuchsine
-
neutral red
-
gentian violet
Frage 23
Frage
Which of the following structure contains genes for enzymes and antibiotic resistance
Antworten
-
plasmld
-
pilli
-
capsules
-
plasma membrane
Frage 24
Frage
Which of the following is the most important structure related to microbial attachment to cells
Antworten
-
flagella
-
plasmid
-
peptidoglycan
-
glycocalix
Frage 25
Frage
Which of the following is not a gram negative microbe
Antworten
-
Clostridum perfringes
-
Vibrio cholerae
-
excheriehia
-
bordetella
Frage 26
Frage
What causes it to be pink
Antworten
-
pheiffer's fuchsine
-
gram iodine
-
crystale violet
-
neisser
Frage 27
Frage
Selective media are designed to
Frage 28
Frage
Which part of the antibody molecule reacts with the antigenic determinant agent
Antworten
-
the fab fragment
-
the fe fragment
-
the constant H region
-
the constants
Frage 29
Frage
The chemical complement pathway is activated by
Antworten
-
microbial endotoxins
-
antigen-antibody complex
-
microbial proteins
Frage 30
Frage
All of the following statement about exotoxins are true expect
Antworten
-
they are produce mainly by gram (+) bacteria
-
they may be neutralized by antitoxins
-
they are proteins
-
they are heat stable at 100*
Frage 31
Frage
In Solid media bacterial growth is detected by observing
Antworten
-
appearance of colonies
-
development of pellet
-
development of turbidity
-
a surface membrane
Frage 32
Frage
The last phase of bacterial growth curve is:
Antworten
-
log phase
-
lag phase
-
stationary phase
-
phase of decline
Frage 33
Frage
Which of the following component is not found in the gram(-) cell wall
Antworten
-
lipopolysaccharide
-
peptidoglycan
-
teichoic acids
-
O antigen
Frage 34
Frage 35
Frage
Klett is a staining procedure for visualizing:
Antworten
-
spores
-
capsules
-
volutine granules
-
nucleotid
Frage 36
Frage
All of the following media are differential except:
Frage 37
Frage
Immunoprophylaxis of tuberculosis includes:
Antworten
-
live affenuated vaccine BCG
-
injection of antimycobacterial serum
-
passive transfer of ready made antibodies from sensitized person
-
a toxoid
Frage 38
Frage
Passive immunization is an application of:
Antworten
-
small doses of infective agent
-
ready made antibodies, formed by another host in response to artificial immunization or to natural infection
-
toxoids
-
killed vaccines
Frage 39
Frage
Which of the following statements about exotoxins are true:
Antworten
-
they are produced mainly by gram(+) bacteria
-
they may be neutralized by antitoxins
-
they are proteins
-
they are heat stable at 100*
Frage 40
Frage
Which of the following is not a distinctive characteristic of viruses
Antworten
-
viruses lack the machinery for protein synthesis
-
viruses require living cells for replication
-
viruses replicate by a process of binary fission
-
viral genomes are either DNA or RNA but not both
Frage 41
Frage
the immune response elicited by Salk’s inactivated polio vaccine is deficient in specific
Antworten
-
secretory lgA
-
serum IgA
-
serum lgM
-
IgG
Frage 42
Frage
All of the following are characteristics of the human immunodeficiency virus(HIV)expect?
Antworten
-
it bind to CD4 molecule preferentially
-
it contains gp120 and gp30 envelope proteins
-
it is the causative agent of AIDS
-
it contains DNA within its core
Frage 43
Frage
Complement fixation test requires
Antworten
-
dissolved antigen
-
corpusculum antigen
-
antitoxin
-
complement
Frage 44
Frage
Which of the immunoglobin molecule is pentamenie
Frage 45
Frage
Resection of the transplanted organ due to preformed antibodies in recipient is defined
Antworten
-
hyper acute
-
aclerated
-
acute
-
chronic
Frage 46
Frage
microorganisms can be defined as living creatures so small that are not visible by eye
Frage 47
Frage
Loffler staining procedure stains bacteria in
Frage 48
Frage
Which of the following is not true related to endotoxins
Frage 49
Frage
Gram negative bacteria differ from gram(+) organism because they passes?
Frage 50
Frage
Most bacteria increase in number through the process of
Antworten
-
binary fission
-
budding
-
sporulation
-
sexual reproduction
Frage 51
Frage
The term “growth” when for microorganism refer to
Frage 52
Frage
All of the following statement about bacteria cell division are true except:
Antworten
-
all bacteria double their number every 1 hour
-
bacterial times are influenced by environmental conditions
-
the two bacterial cells following division are genetically identical, they are ones
-
all the above
Frage 53
Frage
Bacterial nucleotid consist of
Antworten
-
no chromosomes
-
one chromosome
-
several chromosome
Frage 54
Frage
Bacterial capsule can be visual sated by:
Antworten
-
gram stain
-
loeffler stain
-
klett stain
-
moller stain
Frage 55
Frage
Lipopolysacharides can be found in large amount in:
Antworten
-
gram(+) bacterial wall
-
gram (-) bacterial wall
-
both
-
none of above
Frage 56
Frage
Complex methods for bacterial staining are
Antworten
-
Loeffler stain
-
Pfefiffer stain
-
Gram stain
-
ZiehI-Neelsen stain
Frage 57
Frage
Specific identity (serotype) of influenza virus can be accomplished by:
Frage 58
Frage
enlargement of one or both parotid glands in the common clinical manifestation of:
Antworten
-
measles
-
mumps
-
rubella
-
grippe
Frage 59
Frage
The initial replication of human poliovirus starts in:
Frage 60
Frage
In congenital rubella the fetus produce:
Frage 61
Frage
The most common classification system used in microbiology is binomal and was established by:
Antworten
-
Pasteur
-
Koch
-
Linnaeus
-
Gram
Frage 62
Frage
Common pili play role in bacterial;
Antworten
-
conjugation
-
adherence to surface
-
motility
-
precipitation
Frage 63
Antworten
-
found in gram (+) bacteria
-
found in gram(-) bacteria
-
proteins
-
a structural component of the spore
Frage 64
Frage
Which of the following techniques allows to start with a single piece of microbial DNA and produce billions of copies in matter of hour
Antworten
-
PCR
-
ELlSA
-
hybridoma biotechnology
-
IFA
Frage 65
Frage
Which of the following is the fastest way to kill endospores
Antworten
-
autoclave at 121*C
-
hot air at 160*C
-
clorox solution
-
filtration
Frage 66
Frage
Gram positive bacterium is most susceptible to the action of penicillin in the following phase of growth?
Antworten
-
lag
-
log
-
stationary
-
decline
Frage 67
Frage
The primary immune response include participation of?
Frage 68
Frage
The first vaccine was used against:
Antworten
-
measles
-
tuberculosis
-
hepatitis
-
small pox
Frage 69
Frage
The alternative pathway of complement activation is:
Frage 70
Frage
Which of the immunoglobulins mediates the local immunity
Frage 71
Frage
The formation of pharyngeal pseudomembrane is not indicative for
Antworten
-
tuberculosis
-
diphtheria
-
whooping
-
gas gangrene
Frage 72
Frage
The most potent biological toxin known is
Antworten
-
clastridiumbotidinum exotoxin
-
staphylococcus aureus enterotoxin
-
bacillus cereus toxin
-
clostridium perfringes exotoxin
Frage 73
Frage
The special staining method used for microscopic diagnosis of tuberculosis
Antworten
-
Gram
-
Klett
-
Ziehl-Neelsen
-
Moller
Frage 74
Frage
Cytopathic effect is
Antworten
-
killing of bacteria by viruses
-
absorption of red blood cells by surface of cultured cells
-
damage of cultured infected cells and associated morphological change
-
antigen-antibody reaction
Frage 75
Frage
Viruses contain the following type of nucleic acid
Antworten
-
DNA-single strained
-
DNA double strained
-
DNA or RNA
-
both DNA and RNA
Frage 76
Frage
Hepatitis B virus is most often transmitted by
Antworten
-
sexual contact
-
air
-
blood transfusion
-
ticks
Frage 77
Frage
Varicellazinster virus is a member of
Antworten
-
hypersnviridae
-
hepadnaviridae
-
retroviridae
-
paenviridae
Frage 78
Frage
Epstizin Bar Virus is the causative agent of:
Antworten
-
measles
-
mumps
-
rubella
-
infectious mononucleosis
Frage 79
Frage
Sabin's vaccine against poliomyelitis is secretory immunity in the intestine
Frage 80
Frage
Spherical bacteria,arranged in cluster are known as:
Antworten
-
Staphylococci
-
Streptococci
-
Diplococci
-
Vibrios
Frage 81
Frage
Which concentration of ethyl alcohol is the most effective one as disinfectant and antiseptic
Frage 82
Frage
Penicillin specifically inhibits:
Antworten
-
protein synthesis
-
peptidoglyconsynthesis
-
nucleic acid synthesis
-
formation of capsules
Frage 83
Frage
Conjugation differs from transformation and transduction in that it requires a contact between the donor and the recipient:
Frage 84
Frage
Which of the following structure is involved in bacterial attachment to cell surface?
Antworten
-
capsule
-
flagella
-
pilli
-
measurants
Frage 85
Frage
Bacterial growth medium that contains penicillins:
Antworten
-
minimal medium
-
selective medium
-
differential medium
Frage 86
Frage
The antigen-antibody complex activates complement through:
Antworten
-
classical pathway
-
alternative pathway
-
lectin pathway
Frage 87
Frage 88
Frage
The unit of measurement of bacterial size is:
Antworten
-
nanometer
-
micrometer
-
millimeter
-
kilobase
Frage 89
Frage
Bacterial growth curve is generally separated into
Antworten
-
two distinct phase
-
three distinct phase
-
four distinct phase
-
five distinct phase
Frage 90
Frage
Resistance to many antibiotics is carried by:
Antworten
-
R plasmids
-
sex pilli
-
spores
-
capsules
Frage 91
Frage
Which of the following structures are known to protect bacteria from phago... by white blood cells
Antworten
-
flagella
-
spores
-
capsules
-
ribosomes
Frage 92
Frage
Spherical bacteria, arranged in chains are known as:
Antworten
-
staphylococci
-
streptococci
-
neisseria
-
bacilli
Frage 93
Frage
Endotoxins are associated with
Antworten
-
Catalase production
-
Flagella in gram (-) bacteria
-
LPS (lipopolyshoccharide)
-
Capsules in gram (-) bacteria
Frage 94
Frage
The antigenic typing of salmonella spp detects:
Antworten
-
D, Vi and H antigens
-
Protein
-
M protein
-
Endotoxin
Frage 95
Frage
Which of the following test is used to detect delayed type hypersensitivity
Antworten
-
ASO test
-
CFT
-
Mantoux test
-
None of the above
Frage 96
Frage
Which are the most important immunoglobulins at the mucosal surfaces
Frage 97
Frage
Salmonella spp is causative agent of
Antworten
-
typhoid fever
-
cholera
-
paratyphoid fever
-
bacterial dysentery
Frage 98
Frage
There are animal reservoirs for:
Antworten
-
leptosspinosis
-
salmonellosis
-
cholera
-
diphtheria
Frage 99
Frage
Bacteria could be cultured in artificial nutrient media
Frage 100
Frage
The mean doubling time for most bacterium is
Antworten
-
8 hours
-
24 hours
-
20-30 minutes
-
4 weeks
Frage 101
Frage
Dark field microscopy is usually applied for
Antworten
-
stained preperations with irreversion cell between cochser
-
unstrained wet preparation with oil between the conduncer and the slide irreverSion
-
unstained wet properations with water between the condenser and the slide
-
ultra thin reactions of tissue
Frage 102
Frage
Which of the following component contain peptidoglycan?
Antworten
-
Gram(+) cell walls +F
-
DNA
-
Flagella
-
Cytoplasmic membrane
Frage 103
Frage
The clorax solution and ethyl alcohol are example of:
Antworten
-
sterilizing agents
-
disinfection
-
antibiotics
-
base analogs
Frage 104
Frage
Which immunoglobin contain j chain
Antworten
-
IgA and lgG
-
lgM and lgA
-
lgG and IgM
-
lgD and lgG
-
lgE
Frage 105
Frage
Which of the following are DNA viruses?
Antworten
-
adenoviruses
-
picornviruses
-
paramyxoviruses
-
orthomyoviruses
Frage 106
Frage
Which one is considered a vireal disease viral
Antworten
-
herpes simplex type 1
-
herpes simplex type 2
-
rubella vire
-
medual vire
Frage 107
Frage
Which of the following diagnostic markers persist in the blood stream of HBV infected individuals and is found an (imcatox) of infection
Antworten
-
HBsAg
-
anti-HAV antibodies
-
H-2
-
none of the above
Frage 108
Frage
All of the following statement about poliomyelitis are correct except:
Antworten
-
virus is transmitted mainly in respiratory droplets
-
most disease occur apparent sub-clinical infection
-
persistantviremiafam CNS involvement
-
spinal poliomyelitis involves the anterior born cells of the spinal cord
Frage 109
Frage
During the incubation period of the HBV infection which of the following viral diagnostic marker is most abundant in blood and is commonly used for diagnosis
Antworten
-
HBSAg
-
Anti-HAV antibodies
-
Anti-HCV antibodies
Frage 110
Frage
Influenza virus on RNA virus:
Frage 111
Frage
Human herpes virus 2 is usually associated with:
Antworten
-
genital herpes
-
measles
-
rubelia
-
erpes zoster
Frage 112
Frage
Human immunodeficiency virus belongs to:
Antworten
-
adenoviridae
-
retroviridae
-
togruviridae
-
poxviridae
Frage 113
Frage
The presence of low levels lgG but not lgM antibodies to rubella virus in the newborn suggests:
Frage 114
Frage
A four fold or greater increase in autoantibody titer,measured by appropriate available viral diagnostic test and performed on serum collected at time of disease onset and 14 days later would:
Antworten
-
be highly suggestive to the presence of the disease
-
indicate previous infection in healthy person
-
not be sufficient for diagnosis
-
not be informative since the serum specimens were not collected at proper interval of time
Frage 115
Frage
Current acute HAV infection is best diagnosed by the presence of?
Antworten
-
HBgcAg
-
anti-HBcsntibodies
-
IgM anti-HAV
-
delta antigen
Frage 116
Frage
Which of the following microorganisms lack a cell wall
Antworten
-
ram positive cocci
-
gram negative rods
-
richetsia
-
mycoplasma
Frage 117
Frage
All of the following statement are characteristics for group A strepcoccus?
Antworten
-
they are rarely resistaned to paraisitis
-
they produce beta-hemolysis on blood agar
-
they are sensitive to bacitracin
-
they are of the normal environment fiera
Frage 118
Frage
Herpes virus varicella is a member of (zoster) (varicella zoster virus is member of:
Antworten
-
herpes viridae
-
poxviridae
-
hepadnaviridae
-
retroviridae
Frage 119
Frage
Which of the following Viruses cause infection mononucleosis?
Antworten
-
Herpes simplex 1
-
Epstein-barr-viruses
-
CMV
-
Varicella zoster virus
Frage 120
Frage
Type 2 hypersensitivity reactions are
Antworten
-
anaphylactic and atopic
-
comlement-mediated cytolysis
-
immune-complexes mediated
-
cell mediated with participation
Frage 121
Frage
The causative agent of AIDS is:
Antworten
-
Human herpes virus
-
Haemophilus influenzae
-
Human papilloma virus
-
HIV
Frage 122
Frage
Which of the following components contain peptidoglycan?
Antworten
-
Gram (+) cell walls
-
Gram (-) cell walls
-
DNA
-
Cytoplasmic membrane
Frage 123
Frage
Risus sardonicus refers to:
Antworten
-
diphtheria
-
measles
-
tetanus
-
botulism
Frage 124
Frage
Slide agglutination test detects:
Antworten
-
microbial antigens
-
unknown
-
viral particles
-
bacterial phagocytosis
Frage 125
Frage
Protein A is a surface protein covalently bound to most strains of
Frage 126
Frage
Which of the following interferons participate in the .... immune response?
Antworten
-
interferon alpha
-
interferon beta
-
interferon gamma
Frage 127
Frage
The microbiological test that is widely used for the diagnosis of staphylococcal
Frage 128
Frage
Which of the following statements are characteristics for group A streptococci
Antworten
-
they are rarely resistant to penicillin
-
they produce Beta-hemolysis on blood agar
-
they are sensitive to bacitracin
-
they are part of the normal intestinal flora
Frage 129
Frage
Which of the following vaccines is of routine use?
Antworten
-
against smallpox
-
against hepatitis
-
against measles
-
against mumps
Frage 130
Frage
Which of the following vaccines is not of routine use anymore
Frage 131
Frage
Which are is consider venereal disease virus
Antworten
-
herpes simplex type 1
-
herpes simplex 2
-
rubella
Frage 132
Frage
The subspecies group are identified on the basis of
Frage 133
Frage
The main pathogenic factor of clostridium tetani is
Antworten
-
endotoxin
-
exotoxin
-
spores
-
capsule
Frage 134
Frage 135
Frage
Which of the following immunoglobulin is the principal immunoglobin in exocrine secretion?
Frage 136
Frage
The causative agents of tetanus is:
Antworten
-
clostridium difficile
-
clostridium botulinum
-
clostridium perfingens
-
clostridium tetani
Frage 137
Frage
The positive coagulase test for staphylococcus aureus is indicated by:
Frage 138
Frage
This microorganism causes a sexually transmitted disease that can be diagnosed by demonstration of cytoplasmic inclusions in......?
Antworten
-
Chlamydia atrachomatis
-
Candida albicans
-
Trepomena pfedure
-
Neisseria gonorrhoeae
Frage 139
Frage
Viridans streptococci:
Antworten
-
can cause neonatal sepsis
-
are involved in urinary infection in females
-
are the most frequent cause of bacterial endocarditis
-
cause zoonotic disease transmitted to humans primary by contact with animal urine
Frage 140
Frage
Which of the following statement about microbiological diagnosis of diphtheria is correct
Antworten
-
Microorganisms are coagulase positive
-
microscopy from culture on lofller’s medium or tallarite agar would reveal characteristic chinede letter formation
-
microorganisms are impossible to be identified by Neisser stain because of their small size
-
microorganisms are delicate and can be cultured only in ell culture
Frage 141
Frage
Exotoxins play a determinant role in the pathogenesis of each of the following EXCEPT:
Antworten
-
botulism
-
diphtheria
-
tetanus
-
plaque
Frage 142
Frage
Influenza virus belongs to:
Antworten
-
hepado viridae
-
orthomyxoviridae
-
paramyxoviridae
-
hypesviridae
Frage 143
Frage
Which of the following is the leading cause of post transfusion hepatitis producing the highest frequency of chronic disease
Antworten
-
hepatitis A virus (HAV)
-
hepatitls B virus (HBV)
-
hepatitis C virus (HCV)
-
hepatitis D
Frage 144
Frage
Which of the following immunoglobulins has the highest serum level in healthy adults
Frage 145
Frage
Trepanemapallidum is the causative agent of:
Antworten
-
typhoid fever
-
plague
-
syphilis
-
tuberculosis
Frage 146
Frage
The pathogenesis and clinical of primary tuberculosis are characterized by
Antworten
-
cell mediated response with macrophage and lymphocyte infiltrating the focus of infection
-
a complement mediated immune response
-
a humoral mediated immune response
-
an absence of adaptive immune response
Frage 147
Frage
Which form of plague is most likely to be transmitted from human to human:
Antworten
-
typhoidal
-
sylvatic
-
pneumonic
-
ulceroglandular
Frage 148
Frage
Staphylococci differ from streptococci in:
Antworten
-
gram reactivity
-
cell diameter
-
acid fast staining
-
catalase production
Frage 149
Frage
All of the following characteristics of Salmonella typhimurium are true EXCEPT:
Antworten
-
has a multianimal reservoir
-
is one of the most common causes of enterocolitis
-
ferments lactose
-
is a gram (-), molite, endotoxin bearing rod
Frage 150
Frage
Which of the following characteristics concerning influenza A virus is correct
Antworten
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it can always cause generalized infections
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it can always cause encephalitis
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it has the capacity to undergo shift and drift
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it has nonsegmented negative sense genoma
Frage 151
Frage
Hepatitis A virus is most often transmitter by
Antworten
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sexual contact
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contaminated food
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blood transfusion
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shared needles
Frage 152
Frage
All of the following statements are characteristic for group A streptococci EXCEPT:
Antworten
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they are rarely resistant to Penicillin
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they produce beta-hemolysis on blood agar
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they are sensitive to bacitracin
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they are part of the normal intestinal flora