Frage 1
Frage
What is characteristic of the Paget's disease?
Antworten
-
increased osteoblast and osteoclast activity
-
"bone pain" generally in one area, commonly pelvis and spine
-
structurally disorganized bone matrix with both excessive bone mass and bone resorption
-
increased osteoblast but decreased osteoclast activity
-
uniform concentric rings of organized bone matrix
-
"bone pain" spreading out to different areas of the body
Frage 2
Frage
Osteoblasts mature into these cells [blank_start]osteocytes[blank_end] once trapped in the bone matrix; they activate bone formation via [blank_start]altered signalling[blank_end] and apoptosis.
Antworten
-
osteocytes
-
altered signalling
Frage 3
Frage
What do osteoblasts do?
Frage 4
Frage
What is characteristic of osteoclasts?
Frage 5
Frage
Where would you have the most interstitial growth?
Antworten
-
epiphysis
-
metaphysis
-
diaphysis
-
epiphyseal growth plates
-
periosteum
Frage 6
Frage
[blank_start]Interstitial[blank_end] growth is [blank_start]lengthening[blank_end] growth. This is due to increased number of matrix-depositing cells. [blank_start]Appositional[blank_end] growth is [blank_start]widening[blank_end] growth. This is due to increased matrix deposition by the same number cells.
Antworten
-
Interstitial
-
Appositional
-
widening
-
lengthening
Frage 7
Frage
In terms of calcium metabolism, the thyroid releases what hormone?
Frage 8
Frage
Calcitonin causes increased calcium deposition in bone by inhibiting bone resorption.
Frage 9
Frage
What does parathyroid hormone do?
Antworten
-
increase osteoclast activity
-
increase osteoblast activity
-
increase osteocyte activity
-
decrease osteoclast activity
-
decrease osteoblast activity
-
decrease osteocyte activity
Frage 10
Frage
Falling onto an outstretched hand/wrist causes what type of fracture most commonly?
Antworten
-
scaphoid fracture
-
radial styloid fracture
-
humeral fracture
-
3rd metacarpal fracture
-
ulnar styloid process
-
lunate fracture
Frage 11
Frage
What are bones of the hand?
Antworten
-
scaphoid
-
lunate
-
triquetrum
-
pisiform
-
trapezium
-
trapezoid
-
capitate
-
hamate
Frage 12
Frage
What nerve would you damage if you were to break the shaft of the humerus?
Antworten
-
radial
-
axillary
-
musculocutaneous
-
medial
-
ulnar
Frage 13
Frage
If the radial nerve is damaged, how might it present?
Antworten
-
wrist drop even with fully extended forearm/arm
-
inability to abduct arm
-
inability to flex elbow
-
inability to flex shoulder
-
Benedict claw with fully extended forearm/arm
Frage 14
Frage
What does the musculocutaneous innervate muscle-wise?
Antworten
-
flexor muscles of the arm
-
flexor muscles of the forearm
-
extensor muscles of the arm
-
extensor muscles of the forearm
-
3.5 fingers of the hand
Frage 15
Frage
What does the axillary innervate muscle-wise?
Antworten
-
deltoid, teres minor (shoulder muscles)
-
posterior arm flexor muscles
-
posterior forearm extensor muscles
Frage 16
Frage
What does the radial nerve NOT innervate muscle-wise?
Frage 17
Frage
What does musculocutaneous innervate muscle-wise?
Frage 18
Frage
What does ulnar nerve innervate muscle-wise?
Antworten
-
posterior forearm muscles
-
posterior arm muscles
-
anterior forearm muscles
-
anterior arm muscles
-
anterior medial 2 fingers
-
posterior lateral 2 fingers
Frage 19
Frage
If there is loss of elbow flexion (can't flex biceps), there is damage to the [blank_start]musculocutaneous[blank_end] nerve.
Frage 20
Frage
if there is shoulder weakness or you're unable to abduct shoulder, then there is damage to the [blank_start]axillary[blank_end] nerve.
Frage 21
Frage
A hand of benediction is sign of damage to the [blank_start]median[blank_end] nerve.
Frage 22
Frage
Being unable to abduct or adduct the last 2 fingers is indicative of damage to the [blank_start]ulnar[blank_end] nerve.
Frage 23
Frage
What does the ulnar provide sensory innervation to?
Frage 24
Frage
What does the median provide sensory innervation to?
Antworten
-
anterior 3.5 lateral fingers
-
posterior 3.5 lateral fingers
-
anterior 1.5 lateral fingers
-
posterior 1.5 lateral fingers
Frage 25
Frage
What does radial nerve provide sensory innervation to?
Antworten
-
lateral arm
-
posterior forearm
-
posterior hand
-
anterior hand
-
anterior forearm
-
medial arm
Frage 26
Frage
The axillary nerve innervates the...in sensory wise
Frage 27
Frage
Musculocutaneous provides sensory innervation to lateral forearm down to the thenar prominence (at the base of the thumb.)
Frage 28
Frage
Numbness at the back of the wrist and hand is due to damage to the sensory innervation by the [blank_start]radial[blank_end] nerve.
Frage 29
Frage
Damage to the [blank_start]median[blank_end] nerve will lead to parethesia to the lateral 3 anterior fingers.
Frage 30
Frage
Loss of sensation in the median of the hand and the medial first 2 fingers is damage to the [blank_start]ulnar[blank_end] nerve.
Frage 31
Frage
Damage to the radial nerve leads to wrist drop. What are some pathologies in which the radial nerve gets hurt?
Frage 32
Frage
How might you injure the axillary nerve?
Antworten
-
dislocation of the humeral head
-
surgical neck of the humerus fracture
-
dislocation of the clavicle
-
pulling the deltoid muscle
Frage 33
Frage
You might harm the musculocutaneous nerve via a medial epicondyle fracture.
Frage 34
Frage
A winged scapula is indicative of damage to the [blank_start]long thoracic nerve[blank_end] (spinal roots C5-C7.)
Frage 35
Frage
The spinal roots of the musculocutaneous nerve are (in numerical order from least to greatest) are [blank_start]C5[blank_end], [blank_start]C6[blank_end], and [blank_start]C7[blank_end].
Frage 36
Frage
The Axillary nerve is from the roots [blank_start]C5[blank_end] and [blank_start]C6[blank_end] (in numerical order.)
Frage 37
Frage
The radial nerve is from the spinal roots [blank_start]C5[blank_end] to [blank_start]T1[blank_end].
Frage 38
Frage
The ulnar nerve is from the spinal roots of [blank_start]C8[blank_end] and [blank_start]T1[blank_end].
Frage 39
Frage
The spinal roots of the median nerve is [blank_start]C5[blank_end] or [blank_start]C6[blank_end] to [blank_start]T1[blank_end].
Frage 40
Frage
Which of these myotomes and action pairings are correct?
Antworten
-
C4: shoulder elevation
-
C5: chicken abduction (wings)
-
C6: elbow flexion
-
C6: wrist extension
-
C7: elbow extension
-
C7: wrist flexion
-
C8: thumb extension (thumbs up)
-
T1: finger abduction (fanned fingers)
-
C6: wrist flexion
-
C6: elbow extension
Frage 41
Frage
What is true regarding Erb's palsy?
Antworten
-
damage to the upper part of the brachial plexus (C5 and C6)
-
damage to the lower part of the brachial plexus (C7 C8 and T1)
-
motorbike accidents can cause this
-
improper birthing techniques (pull baby's head against pelvic bones while labor) can cause this
-
landing on an outstretched arm from a big height can cause this
-
results in a "waiter's tip"
-
results in a "clawed hand"
-
damage to the axillary nerve
-
damage to the suprascapular nerve
-
damage to the musculocutaneous nerve
Frage 42
Frage
What is the myasthenia gravis?
Antworten
-
At the neuromuscular junction, the body produces antibodies against the acetylcholine receptors
-
Intense morning sickness that needs anti-emetics as treatment
-
the gradual degradation of muscle fibers, starting from top of the head to bottom of the feet
-
loss of sensation in some or all motor units of certain muscles
Frage 43
Frage
How might myasthenia gravis present?
Frage 44
Frage
How would you manage myasthenia gravis?
Antworten
-
acetylcholine esterase inhibitors
-
acetylcholine reuptake enhancers
-
acetylcholine esterase activators
-
acetylcholine agonists
Frage 45
Frage
The [blank_start]abdominal aorta[blank_end] bifurcates into the [blank_start]right common illiac[blank_end] and the [blank_start]left common illiac[blank_end]. The right illiac again bifurcates into the [blank_start]internal illiac[blank_end] and the [blank_start]external illiac[blank_end]. The external illiac becomes the [blank_start]right femoral[blank_end], which is the deep artery of the right thigh. In the popliteal fossa, the right femoral becomes the right [blank_start]popliteal[blank_end] artery. The right popliteal further bifurcates into the [blank_start]right anterior tibial[blank_end] and the [blank_start]right posterior tibial.[blank_end] The right posterior tibial, which is the pulse felt at the ankle, becomes the [blank_start]posterior right fibular.[blank_end] The right anterior tibial becomes the right [blank_start]dorsalis pedalis[blank_end].
Frage 46
Frage
Which of the following could cause carpal tunnel syndrome?
Antworten
-
pregnancy
-
rheumatoid arthiritis
-
repetitive use of hands
-
septic arhritis
-
osteomalacia
-
osteoporosis
Frage 47
Frage
Compression of the [blank_start]median[blank_end] nerve as it travels through the [blank_start]carpal[blank_end] [blank_start]tunnel[blank_end] in the wrist is Carpal Tunnel Syndrome.
Frage 48
Frage
How does Carpal Tunnel Syndrome present?
Frage 49
Frage
What are management options of the carpal tunnel syndrome?
Antworten
-
local corticosteroids
-
night time splinting
-
day time splinting
-
anabolic steroids
-
always surgical decompression
-
if severe surgical decompression
-
avoid further injury via strain
Frage 50
Frage
What are the nerves of the lower limb?
Frage 51
Frage
The [blank_start]sural[blank_end] nerve only innervates sensory-wise. It innervates the skin of the [blank_start]posterior[blank_end] leg and [blank_start]lateral[blank_end] foot.
Frage 52
Frage
What does the sciatic innervate muscle-wise?
Antworten
-
the posterior compartment of the thigh
-
the anterior compartment of the thigh
-
lateral compartment of the thigh
-
the medial compartment of the thigh
Frage 53
Frage
What does the femoral nerve innervate muscle-wise?
Antworten
-
anterior thigh
-
posterior thigh
-
lateral thigh
-
medial thigh
Frage 54
Frage
What does the obturator nerve innervate muscle wise?
Antworten
-
anterior thigh
-
posterior thigh
-
lateral thigh
-
medial thigh
Frage 55
Frage
What does the common fibular deep branch innervate muscle wise?
Antworten
-
anterior leg
-
posterior leg
-
lateral leg
-
medial leg
Frage 56
Frage
What does the superficial branch of the common fibular innervate muscle-wise?
Antworten
-
anterior leg
-
posterior leg
-
lateral leg
-
medial leg
Frage 57
Frage
What does the tibial nerve innervate muscle-wise?
Antworten
-
posterior leg
-
anterior leg
-
medial leg
-
lateral leg
-
sole of the foot
-
top of the foot
Frage 58
Frage
The femoral nerve's sensory innervation includes the [blank_start]anterior[blank_end] thigh and [blank_start]medial[blank_end] leg.
Frage 59
Frage
The obturator nerve's sensory innervation is the [blank_start]medial[blank_end] thigh.
Frage 60
Frage
The [blank_start]deep[blank_end] branch of the common fibular's sensory innervation is the skin of the upper lateral leg.
Frage 61
Frage
The deep branch of the common fibular's sensory innervation is the [blank_start]lower[blank_end] [blank_start]lateral[blank_end] leg and [blank_start]dorsal[blank_end] foot.
Frage 62
Frage
Both the [blank_start]sciatic[blank_end] nerve (which bifurcates in the [blank_start]popliteal[blank_end] fossa into the [blank_start]tibial[blank_end] nerve and the common fibular nerve) and the [blank_start]tibial[blank_end] nerve innervate (sensory-wise) the [blank_start]posterior[blank_end] thigh and [blank_start]posterior[blank_end] leg and [blank_start]plantar[blank_end] foot.
Antworten
-
sciatic
-
popliteal
-
tibial
-
tibial
-
posterior
-
posterior
-
plantar
Frage 63
Frage
The sciatic nerve's spinal roots are [blank_start]L4-S3[blank_end].
Antworten
-
L4-S3
-
L2-S3
-
L1-L2
-
L3-S2
-
L4-S2
Frage 64
Frage
Dorsiflexion is a sign of damage to what nerve?
Frage 65
Frage
Inability to dorsiflex (so basically having a foot drop) is indicative of damage to what nerve?
Frage 66
Frage
What movements does the femoral nerve allow?
Antworten
-
flexion of hips
-
extension of the knee
-
extension of the hips
-
flexion of the knees
-
abduction of the leg
-
adduction of the leg
Frage 67
Frage
What innervates hip extension and knee flexion?
Antworten
-
Inferior gluteal
-
sciatic nerve
-
superior gluteal
-
tibial
-
common fibular
Frage 68
Frage
The [blank_start]obturator[blank_end] nerve allows hip adduction. On the other hand, the [blank_start]superior[blank_end] [blank_start]gluteal[blank_end] nerve allows hip abduction.
Antworten
-
obturator
-
superior
-
gluteal
Frage 69
Frage
What are the main types of arthritis?
Frage 70
Frage
[blank_start]Primary[blank_end] osteoarthritis and [blank_start]secondary[blank_end] osteoarthritis are the two types of osteoarthritis.
Frage 71
Frage
The three types of inflammatory arthritis: rheumatoid, [blank_start]crystal-induced,[blank_end] and [blank_start]psoriatic[blank_end].
Antworten
-
crystal-induced,
-
psoriatic
Frage 72
Frage
What are the two types of crystal-induced arthritis?
Antworten
-
gout
-
pseudogout
-
rheumatoid
-
psoriatic
-
none of the above
Frage 73
Frage
What is a degenerative disease that affects the joints, often due to wear and tear of articular cartilage?
Antworten
-
osteoarthritis
-
synovitis
-
crepitus
-
joint stiffness
-
subarticular sclerosis
Frage 74
Frage
How might osteoarthritis present?
Antworten
-
joint stiffness in the evening/morning
-
generally worse after walking
-
palpable bony swelling on the hands' interphalangeal joints
-
reduced range of motion
-
crepitus in the joints
-
insomnia
-
generalized swelling around major joints
-
locked joints
-
synovitis
Frage 75
Frage
An X-ray investigation of osteoarthritis will show...
Antworten
-
reduced joint space
-
subarticular sclerosis
-
osteophytes
-
bony cysts
-
glued up joint space
-
cartilage cysts
-
osteocytes
Frage 76
Frage
For osteoarthritis, the only management is supportive/palliative.
Frage 77
Frage
What is an autoimmune disease that also ends in joint destruction?
Antworten
-
rheumatoid arthritis
-
septic arthritis
-
osteoarthritis
-
gout
Frage 78
Frage
What is characteristic of rheumatoid arthritis?
Antworten
-
specific joint pain in the morning
-
specific joint pain in the evening
-
joints affected symetrically
-
joint inflammation
-
joints affected asymetrically
Frage 79
Frage
All of these are part of the management of rheumatoid arthritis BUT
Frage 80
Frage
Which of the following regarding the investigation of rheumatoid arthritis is true?
Antworten
-
will find rheumatoid factor in serum
-
x-ray will reveal bone erosion
-
x-ray will reveal reduced joint space
-
periarticular osteopenia
-
visible deformity
-
x-ray will reveal
-
excessive bone growth
Frage 81
Frage
The deposition of monosodium urate crystals in joints is a type of arthritis called [blank_start]gout[blank_end]. This usually happens if there are high levels of [blank_start]uric[blank_end] acid in the blood. The risk factors are [blank_start]obesity[blank_end] and [blank_start]purine[blank_end] (one of the building blocks of DNA) rich food. The most common occurence is at the big [blank_start]toe[blank_end] joint. Symptoms include [blank_start]synovitis[blank_end] (swelling of the joint), [blank_start]malaise[blank_end] (general ill-feeling), and [blank_start]tophi[blank_end] [blank_start]lumps[blank_end] (crystals.) These crystals are visible under polarized light microscopy. The primary way to test for this is to take [blank_start]aspirate[blank_end] fluid in the joint, gram stain it to rule out septic arthritis, and test the fluid for levels of uric acid.
Antworten
-
gout
-
uric
-
purine
-
obesity
-
toe
-
synovitis
-
malaise
-
tophi
-
lumps
-
aspirate
Frage 82
Frage
The treatment plan is for what?
1. NSAIDs
2. Colchicine
3. Corticosteroids
Antworten
-
chronic gout
-
acute gout
-
goutisis
-
pseudogout
Frage 83
Frage
Other than lifestyle changes to reduce urate levels, we give those with [blank_start]chronic[blank_end] [blank_start]gout[blank_end] the drug allopurinol.
Frage 84
Frage
Accumulation of monosodium urate monohydrate crystals in joints causes pseudogut as well.
Frage 85
Frage
What is of clinical importance regarding septic arthritis?
Antworten
-
medical emergency
-
take the aspirate fluid in join and gram stain it
-
take a blood culture (full blood count) and see if there's a high amount of leukocytes
-
take a blood culture (full blood count) and see if there's a high amount of c-reactive protein
-
x-ray will show increased joint space
-
x-ray will show decreased joint space
-
chronic/gradual development
-
to manage, should drain aspirate fluid
-
to manage, should give antibiotics
-
presents like an infection plus reduced joint functionality and synovitis
Frage 86
Frage
Prostacyclin is prostaglandin [blank_start]12[blank_end], which is produced by the [blank_start]epithelium[blank_end]. Prostacyclin prevents excess [blank_start]platelet[blank_end] [blank_start]aggregation[blank_end] during the platelet plug.
Antworten
-
12
-
epithelium
-
platelet
-
aggregation
Frage 87
Frage
[blank_start]Thrombocytoplenia[blank_end] is when there are too few platelets in the body. It can be treated with [blank_start]thrombopoietin[blank_end], which will increase the platelet number. It takes [blank_start]6[blank_end] days for progress to be apparent though.
Antworten
-
Thrombocytoplenia
-
thrombopoietin
-
6
Frage 88
Frage
Platelets only adhere to smooth epithelial surfaces.
Frage 89
Frage
[blank_start]Von[blank_end] [blank_start]Willebrand[blank_end] Disease is when a person is missing vWF and therefore have difficulty with [blank_start]hemostasis[blank_end] (the stopping of bloodloss.)
Antworten
-
Willebrand
-
Von
-
hemostasis
Frage 90
Frage
If there is a suspicion of liver disease, one should check if [blank_start]coagulation[blank_end] is affected because it very well could be.
Frage 91
Frage
Coagulation can be affected in:
diseases affecting [blank_start]protein[blank_end] [blank_start]formation[blank_end]
[blank_start]genetic[blank_end] diseases of the clotting [blank_start]factors[blank_end]
Antworten
-
protein
-
formation
-
genetic
-
factors
Frage 92
Frage
There are 2 coagulation pathways: they meet up at factor [blank_start]10[blank_end].
The intrinsic pathway begins with factor [blank_start]12[blank_end]. This is when the [blank_start]inside[blank_end] of the blood vessel gets damage without any necessary external damage. Ex: [blank_start]hypertension[blank_end] (erodes.)
The extrinsic pathways begin with factor [blank_start]3[blank_end]. Damage from [blank_start]outside[blank_end] to the blood vessel. Usually accompanies tissue damage.
Antworten
-
10
-
12
-
3
-
hypertension
-
inside
-
outside
Frage 93
Frage
The outside aspect of a scab is called an [blank_start]eschar[blank_end].
Frage 94
Frage
What is true regarding vitamin K?
Antworten
-
produces anticoagulant protein c
-
produces coagulant protein z
-
produces anticoagulant protein s
-
produces factor 7
-
produces factor 9
-
produces prothrombin
-
produces factor 10
-
produces fibrinogen
-
produces factor 5
Frage 95
Frage
Vitamin K helps with bone metabolism by increasing calcification.
Frage 96
Frage
Vitamin K is from kale and kiwi.
Frage 97
Frage
Vitamin K is stored in muscle
Frage 98
Frage
The "tea and toast" diet is associated with vitamin [blank_start]B[blank_end][blank_start]12[blank_end] deficiency. Patients can present as [blank_start]weakness[blank_end], paresthesia (tingliness), and [blank_start]irritability[blank_end]. Vegetarians and [blank_start]vegans[blank_end] often have this. B12 helps make the [blank_start]myelin[blank_end] [blank_start]sheath[blank_end] in neurons.
Antworten
-
B
-
12
-
weakness
-
irritability
-
myelin
-
sheath
-
vegans
Frage 99
Frage
[blank_start]Allodynia[blank_end] is when the patient complains that "everything" is painful, even stimuli that are not usually painful.
Frage 100
Frage
[blank_start]Hyperalgesia[blank_end] is when you have an increased pain response to painful stimulus.
Frage 101
Frage
Primary healing is when you actively bring together both edges of the wound to stimulate heealing.
Frage 102
Frage
Secondary healing is when you leave the wound alone to heal
Frage 103
Frage
Warfarin is given following
Antworten
-
a prothrombin time test
-
a K reductase time test
-
a Synacthen test
-
a plasmin time test
-
a water deprifation test
Frage 104
Frage
Warfarin is an anticoagulant.
Frage 105
Frage
Warfarin works essentially by blocking the enzyme [blank_start]vitamin[blank_end] [blank_start]K[blank_end] [blank_start]reductase[blank_end], and thus blocks all the stuff said vitamin makes. It is prescribed for heart conditions--such as [blank_start]atrial[blank_end] [blank_start]fibrillation[blank_end]--and for thrombotic conditions--[blank_start]deep[blank_end] [blank_start]vein[blank_end] thrombosis and [blank_start]pulmonary[blank_end] embolisms are the classics. Also, it is given post [blank_start]orthopedic[blank_end] surgery.
Antworten
-
vitamin
-
K
-
reductase
-
atrial
-
fibrillation
-
deep
-
vein
-
pulmonary
-
orthopedic
Frage 106
Frage
Vitamin K enhances the functionality of Warfarin.
Frage 107
Frage
Antithrombin III deficiency is a hereditary, relatively harmless, and common condition.
Frage 108
Frage
DVT and pulmonary embolisms are both complications of Antithrombin III deficiency.
Frage 109
Frage
Warfarin acts on the thrombus by dissolving it.
Frage 110
Frage
TPA ([blank_start]tissue[blank_end] [blank_start]plasminogen[blank_end] [blank_start]activator[blank_end]) is used in drugs dealing with thrombotic problems. It [blank_start]dissolves[blank_end] the clot.
Antworten
-
tissue
-
plasminogen
-
activator
-
dissolves
Frage 111
Frage
What causes Hemophilia A?
Antworten
-
Factor 8 deficiency
-
Factor 9 deficiency
-
Factor 12 deficiency
-
Factor 5 deficiency
Frage 112
Frage
What is Hemophilia B due to?
Antworten
-
Factor 7 deficiency
-
Factor 5 deficiency
-
Factor 9 deficiency
-
Factor 11 deficiency
Frage 113
Frage
[blank_start]Vasculogenesis[blank_end] is the formation of new blood vessels completely from scratch from [blank_start]endothelial[blank_end] precursor cells.
Antworten
-
Vasculogenesis
-
endothelial
Frage 114
Frage
Myofibroblasts need a lot of extracellular matrix.
Frage 115
Frage
Mature tissue contains [blank_start]dense[blank_end] collagen (collagen [blank_start]I[blank_end]) and blood channels. It is [blank_start]acellular[blank_end] connective tissue.
Frage 116
Frage
What is true regarding Hypertrophic scars?
Frage 117
Frage
What is true regarding contracture scars?
Frage 118
Frage
What is true regarding keloid scars?
Frage 119
Frage
Sunken scars have a [blank_start]pitted[blank_end] kind of appearance. An example: [blank_start]chickenpox[blank_end] scars.
Frage 120
Frage
Scar treatment is often unecessary.
Frage 121
Frage
Which of these are ways to treat scars?
Antworten
-
topical silicone gel
-
pressure dressings
-
steroids
-
make- up
-
cosmetic surgery
-
plastic surgery
-
flucloxacillin
-
acupuncture