Frage 1
Frage
Indicate the correct statement(s)
Antworten
-
granulation tissue is rich of capillaries and cells
-
granulation tissue is rich in collagen fibres and fibroblasts and contains less blood vessels
-
granulation tissue is the immature connective tissue
-
fibrous tissue is immature connective tissue
Frage 2
Frage
What is hyper-granulation?
Frage 3
Frage 4
Frage 5
Frage
Which stain can be used to prove of scarring (cicatrix) of the heart?
Antworten
-
Van Gieson
-
Peris
-
Congo Red
-
PAS
Frage 6
Frage
Which of the could not be seen in rheumatoid nodules?
Antworten
-
Fibrinoid necrosis
-
Epitheloid cells
-
Langhans cells
-
Lymphocytes
Frage 7
Frage
Indicate the correct statement(s) for the polyarteriitis nodosa.
Antworten
-
it is an autoimmune disease
-
it affects mostly the elastic arteries
-
there is accumulation of glucosaminoglycans in the vessel walls which can be demonstrated with metachromasia with Toluidin Bleu
-
the branches of the pulmonary arteries are affected
Frage 8
Frage
Anaphylactic hypersensitivity reactions are related to:
Antworten
-
Hemolytic anemia
-
Hashimoto thyroiditis
-
Allergic rhinitis
-
Bronchial asthma
Frage 9
Frage
Cytotoxic hypersensitivity reactions are related to:
Antworten
-
hashimoto thyroiditis
-
hemolytic anemia
-
allergic rhinitis
-
nodosal poyarteriitis
Frage 10
Frage
Immune complexes mediated hypersensitivity reactions are related to:
Antworten
-
polyartheriitis nodosa
-
rheumatoid arthritis
-
hemolytic anemia
-
tuberculosis
Frage 11
Frage
Cell mediated hypersensitivity reactions are related to:
Antworten
-
Tuberculosis
-
Polyarteriitis nodosa
-
Bronchial asthma
-
Hashimoto thyroiditis
Frage 12
Frage
Indicate characteristics of the benign tumors.
Frage 13
Frage
Indicate characteristics of the benign tumors
Antworten
-
infiltrative growth
-
slow, long term developntcnt
-
usually they don't recur after complete surgery
-
their microscopic structure shows only tissue atypia
Frage 14
Frage
Indicate correct characteristics of the malignant tumors.
Frage 15
Frage
Indicate correct characteristics of the malignant tumors.
Frage 16
Frage
Which is the most common way of metastasizing of epithelial tumors?
Frage 17
Antworten
-
malignant tumor of the covering epithelium
-
benign tumor of glandular epithelium
-
benign tumor of cover type epithelium
-
benign soft tissue tumor
Frage 18
Frage
Indicate the correct characteristic(s) for papilloma
Antworten
-
it has tree-like stroma covered by differentiated stratified squamous epithelium
-
it has tree-like stroma covered by undifferentiated squamous epithelium with signs of cell atypia
-
stroma and parenchyma are difficult to distinguish
-
it doesn't have a capsule
Frage 19
Frage
What is the term used for malignant tumors of cover type epithelium?
Antworten
-
adenocarcinoma
-
papilloma
-
carcinoma
-
sarcoma
Frage 20
Frage
What is the term used for malignant tumors of glandular type epithelial origin?
Antworten
-
adenocarcinoma
-
adenoma
-
carcinoma
-
carcino-adenoma
Frage 21
Frage
What is the term used for benign tumors of glandular type epithelial origin?
Antworten
-
papilloma
-
adenoma
-
teratoma
-
adenocarcinoma
Frage 22
Frage
Point the correct statement(s) about basal cell carcinoma.
Antworten
-
it develops only on the skin
-
it can develop at any place with squamous epithelium
-
it characterizes with early lymphogenic and hematogenic metastases
-
very often it recurs at the same place after surgery
Frage 23
Frage
Keratinized squamous cell carcinoma:
Antworten
-
develops only on the skin
-
can develop at any place with squamous epithelium
-
is highly undifferenciated malignant tumor
-
is a tumor composed of more differenciated cells with keratin production
Frage 24
Frage
What kind of structures are the cancer perls?
Antworten
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accumulation of keratin produced by more differentiated malignant cells originating from squamous epithelium
-
pink-coloured homogenous substance located in the centre of the tumor nests
-
accumulation of mucus produced by highly undifferentiated malignant cells located in the centre of the tumor nests
-
pink homogenous substance that accumulates in the stroma of the tumor
Frage 25
Frage
The gross appearance of which tumor is called "ulcus rodens"?
Antworten
-
squamous cell carcinoma
-
melanoma
-
basal cell carcinoma
-
adenocarcinoma
Frage 26
Frage
Squamous cell carcinoma develops in the lung after:
Frage 27
Frage
Indicate the correct microscopic features of cell atypia
Antworten
-
polymorphism of cells and nuclei
-
low nucleus-cytoplasm index
-
typical mitoses
-
monster cells, hyperchromasia and polychromasia of nuclei
Frage 28
Frage
What are the characteristics of the nuclei of the malignant tumors?
Frage 29
Frage
Papillary carcinoma of the urinary bladder arises from:
Antworten
-
squamous epithelium
-
transitional epithelium
-
glandular epithelium
-
smooth musculature
Frage 30
Frage
What is carcinoma in situ?
Antworten
-
malignant tumor limited to the epithelium above the basal membrane
-
malignant tumor destroying the basal membrane but spreading no more than 5mm below it
-
benign tumor limited to the basal membrane
-
benign tumor of a great size compressing the surrounding tissues
Frage 31
Frage
What type of atypia could be seen in the benign tumors of glandular epithelium?
Frage 32
Frage
Which staining is used for proving mucus production from gelatinous adenocarcinoma?
Frage 33
Frage
Pericanalicular and intracanalicular are types of:
Frage 34
Frage
Kruckenberg tumors are:
Antworten
-
metastases from colon adenocarcinoma in the ovaries
-
metastases from pancreatic adenocarcinoma in the ovaries
-
metastases from gastric carcinoma in the ovaries
-
metastases from hepatocellular carcinoma in the ovaries
Frage 35
Frage
Pleomorphic adenoma could be seen mainly:
Frage 36
Frage
Indicate the correct statements about fibroadenoma of the breast.
Antworten
-
capsulated and lobulated tumor
-
non-capsulated malignant tumor with invasive growth
-
microscopically it has two types -- intracanalicular and pericanalicuJar
-
seen in older women
Frage 37
Frage
Mark the correct statements about papillary cystadenoma of the ovary:
Antworten
-
malignant tumor
-
has cyst-like and papillary structures
-
histological characteristics include serous and mucinous types
-
it is a physiological change related to menstrual cycle
Frage 38
Frage
'Linitis plastica' is a gross subtype of:
Antworten
-
gastric cancer
-
pancreatic cancer
-
breast cancer
-
uterine cancer
Frage 39
Frage
Grossly adenocarcinoma of the colon can be:
Antworten
-
polypoid
-
ulcerous
-
nodular
-
all of the listed above
Frage 40
Frage
The terms "early cancer" and "advanced cancer" are used for:
Frage 41
Frage
Malignant tumors from soft tissue are called:
Frage 42
Frage
Indicate the characteristics of the sarcomas.
Antworten
-
seen in older age
-
grossly they look like "fish meat"
-
they give early hematogenic metastases
-
parenchyma and stroma are equally distributed
Frage 43
Frage
Mark the characteristics of the carcinomas.
Antworten
-
seen in young people
-
they metastasize by the blood flow first
-
grossly they have granular surface
-
parenchyma and stroma are equally distributed
Frage 44
Frage
What kind of sarcoma could be seen in an immune deficiency?
Antworten
-
Kaposi sarcoma
-
Ewing sarcoma
-
Rhabdomyosarcoma
-
Chondrosarcoma
Frage 45
Frage
Which of the following sarcomas have the worst prognosis?
Antworten
-
liposarcoma
-
ostesarcoma
-
fibrosarcoma
-
leiomysarcoma
Frage 46
Frage
What staining can be used to distinguish leiomyoma uteri from fibroma?
Frage 47
Frage
Point the characteristics of the leiomyosarcoma.
Frage 48
Antworten
-
benign tumor of vascular origin
-
benign tumor originating from brown fat tissue
-
benign tumor originating from striated muscles
-
malignant tumor originating from pigment tissue
Frage 49
Frage
What are the signs of the atypia in a nevus?
Antworten
-
asymmetry of the lesion, irregular borders
-
dark color, irregular color of the lesion
-
diameter less than 5mm
-
regular borders
Frage 50
Frage
How should a biopsy be done if there is a suspicion for the melanoma?
Antworten
-
incision biopsy
-
punch biopsy
-
excision biopsy
-
brush biopsy
Frage 51
Frage
Point the most common localizations of the teratomas.
Antworten
-
ovaries, testis
-
extremities
-
retroperitoneum
-
mediastinum
Frage 52
Frage
Which of the following are organoid teratomas
Antworten
-
nephroblastoma
-
cholesteatoma
-
dermoid cyst
-
branchiogcnic cyst
Frage 53
Frage
Which of the following is organismoid teratoma
Antworten
-
epidermoid cyst
-
teratocarcinoma
-
dermoid cyst
-
nefroblastoma
Frage 54
Frage
What is a nevus pigmentosus?
Frage 55
Frage
What is a melanoma?
Antworten
-
malignant congenital tumor
-
benign tumor composed of melanocytes
-
malignant tumor of pigment origin
-
none of the above
Frage 56
Frage
What is an achromatic melanoma?
Antworten
-
benign form of melanoma
-
melanoma without melanin in the tumor cells
-
type of melanoma which can be proved with immunohistochemical tests
-
melanoma which is more differentiated
Frage 57
Frage
Point possible localizations of the nevus pigmentosus and melanoma.
Antworten
-
skin
-
uvea
-
meninges
-
all of the above
Frage 58
Frage
Lentigo maligna, nodular, superficial, acral lentigenous are gross forms of:
Frage 59
Frage
Indicate immunohistochemical stains to prove melanoma
Antworten
-
HMB-45
-
Ca-125
-
S-100
-
Cytokeratin
Frage 60
Frage
Which of the following tumors do not have a stroma
Antworten
-
choriocarcinoma
-
seminoma
-
nephroblstoma
-
neuroblastoma
Frage 61
Frage
Indicate types of nevus pigmentosus:
Antworten
-
acquired and congenital
-
junctional, compound, intradermal
-
benign and malignant nevus
-
ectodermal and endodermal nevus
Frage 62
Antworten
-
lipidogenic pigment
-
proteinogenic pigment
Frage 63
Frage
Where is lipofuscin deposited?
Antworten
-
intracellularly
-
extracellularly
Frage 64
Frage
The frozen section ('gefrir') is:
Frage 65
Frage
The term „pathognomonic change" means:
Frage 66
Frage
Most likely the cause of centrolobular fatty degeneration of hepatocytes is:
Antworten
-
diabetes
-
intoxication
-
hypoxia
-
overfeeding
Frage 67
Frage
Hyaline — droplet degeneration has following characteristics:
Frage 68
Frage
What pigment is formed in the center of the hematoma?
Antworten
-
hemosiderin
-
lipofuscin
-
hemomelanin
-
hematoidin
Frage 69
Frage
In which blood vessels are formed most frequently mixed thrombi?
Antworten
-
large veins
-
arteries
-
capillaries
-
venules
Frage 70
Frage
Squamous cell carcinoma occurs most frequently in:
Antworten
-
stomach
-
skin
-
bladder
-
larynx
Frage 71
Frage
Hyperemic-hemorrhagic zone occurs in:
Antworten
-
tophi urici
-
nodular amyloidosis
-
anemic infarction
-
pneumonia
Frage 72
Frage
Which types of bleeding occur in the digestive system?
Antworten
-
hemothorax
-
hemoptysis
-
melena
-
hematemesis
Frage 73
Frage
Which of the following cell damages are irreversible?
Antworten
-
necrosis
-
apoptosis
-
vacuolar degeneration
-
cellular edema
Frage 74
Frage
Left ventricular hypertrophy can develop in:
Antworten
-
cor pulmonale
-
systemic hypertension
-
mitral stenosis
-
aortic stenosis
Frage 75
Frage
Cancer cells which show no resemblance to the tissue from which the tun originates are called:
Frage 76
Frage
Which of the following is correct for the mechanical jaundice?
Antworten
-
indirect bilirubin prevails in blood
-
elevated urine urobilinogen
-
elevated urine bilirubin
-
stools are hyperpigmented
Frage 77
Frage
Basal cell carcinoma is localized most frequently on:
Frage 78
Frage
Caseous necrosis is characteristic for:
Antworten
-
specific inflammation
-
tuberculosis
-
enzyme fat necrosis
-
chronic pyelonephritis
Frage 79
Frage
Bilaterally, on the skin of the eyelids of a young woman are seen yellow nodules with the size of a grain of rice. What is it?
Antworten
-
xanthelasmas
-
nevus
-
efelides
-
hemosiderin deposition
Frage 80
Frage
Which of the following are protein accumulations?
Frage 81
Frage
Hemorrhagic infarction develops in:
Frage 82
Frage
How do we call the local depigmentation of the skin?
Antworten
-
vitiligo
-
hemosiderosis
-
albinism
-
ohronosis
Frage 83
Frage
What kinds of techniques are used for the detection of the lipids:
Antworten
-
freezing microtome
-
paraffin method
-
alcohol fixation
-
staining with Sudan Ill
Frage 84
Frage
The sequence of local structural changes in a disease is called
Antworten
-
sanogenesis
-
pathogenesis
-
tanatogenesis
-
morphogenesis
Frage 85
Frage
" Tiger Heart " is diagnosed when:
Antworten
-
subepicardial fat is increased
-
yellowish lines in the papillary muscles are seen
-
the interventricular septum is injured
-
infarcted area of the left ventricle in seen
Frage 86
Frage
Which of the following is correct for the mechanical jaundice:
Antworten
-
it is parenchymal jaundice
-
there is posthepatic occlusion
-
direct bilirubin is increased
-
it is also called hemolytic jaundice
Frage 87
Frage
The risks involved in fast draining of large quantities of acistes are:
Antworten
-
development of low oncotic pressure edema
-
bleeding into the abdominal cavity
-
massive arterial hyperemia in the abdominal vessels
-
hemodynamic collapse
Frage 88
Frage
"Mutilation" means :
Antworten
-
form of biological mutation
-
pendulum movement of the blood
-
zonal hair loss
-
self amputation of phalanges
Frage 89
Antworten
-
concentric hypertrophy is also called tonogenic
-
eccentric hypertrophy is myogenic
-
hypertrophy can be combined with hyperplasia
-
false type of hypertrophy is hyperplasia
Frage 90
Frage
Sources of fat embolism in the lung are
Antworten
-
the bone marrow in the long bones
-
subcutaneous fat
-
liver with fatty degeneration
-
ulcerated atherosclerotic plaque of the aorta
Frage 91
Frage
Which of these factors lead to nutmeg liver?
Frage 92
Frage
In the bronchi and nasal cavity may develop squamous cell carcinoma based on:
Frage 93
Frage
Amyloid demonstates following characteristics:
Antworten
-
identified with Tioflavin S in fluorescence
-
shows metachromasia with Perls
-
identified with Congo rot in polarized light
-
ultrastructurally has fibrillary structure
Frage 94
Frage
Anaphylactic shock occurs in:
Antworten
-
hypersensitivity reactions cytotoxic type
-
response induced by immune complexes
-
atopic reactions
-
delayed type hypersensitivity
Frage 95
Frage
A basal cell carcinoma is localized most frequently on:
Frage 96
Frage
Reaction for Prussian blue is used for:
Antworten
-
tattoos
-
proof of bilirubin
-
proof of hemosiderin
-
in hemochromatosis
Frage 97
Frage
How could an air embolism be proved:
Antworten
-
in the presence of witnesses
-
autopsy in a bathtub
-
puncturing the right ventricle
-
puncturing of the left ventricle
Frage 98
Frage
Which enzymes are involved in a melanogenesis?
Antworten
-
hyaluronidase
-
tvrosinase
-
dopa oxidase
-
lipase
Frage 99
Frage
Infarctions of which organs could often lead to the death of the patient?
Antworten
-
renal infarction
-
infarction of the spleen
-
infarction of heart
-
cerebral infarction
Frage 100
Frage
In cancers with epithelial origin: