12498370
Beschreibung
Quiz von Alannah McDonnell, aktualisiert more than 1 year ago
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Erstellt von Alannah McDonnell
vor fast 7 Jahre
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Frage 1
Frage
How much alcohol is absorbed in the stomach
Antworten
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20%
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90%
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5%
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0.5%
Frage 2
Frage
How much alcohol is metabolized by the liver?
Antworten
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20%
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90%
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5%
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0.5%
Frage 3
Frage
How much alcohol is excreted by urine?
Antworten
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20%
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90%
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5%
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0.5%
Frage 4
Frage
How is alcohol absorbed along the entire GI tract?
Antworten
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simple diffusion
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active transport
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osmosis
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ion gated channels
Frage 5
Frage
What do alcoholic beverages primarily consist of?
Antworten
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water
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starch
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ethanol
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sugar
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protein
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lipids
Frage 6
Frage
Which of these factors will allow you to drink more alcohol for a lower blood alcohol level content?
Antworten
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weight
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Male
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Female
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empty stomach
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full stomach
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carbonated mixers
Frage 7
Frage
Which of the following statements is true?
Antworten
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Class 1 ADHs have a low Km for ethanol
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Class 1 ADHs have the lowest specificity for EtOH
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CYP2E1 has a lower Km for ethanol than class 1 ADHs
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Chronic alcohol consumption suppresses P450 enzyme systems
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Acute effects of ethanol arise from the increased NAD+/NADH ratio
Frage 8
Frage
What are the two primary pathways of alcohol metabolism?
C[blank_start]ytosol[blank_end] A[blank_start]lcohol[blank_end] D[blank_start]ehydrogenade[blank_end] (ADH)
M[blank_start]icrosomal[blank_end] ethanol-o[blank_start]xidizing[blank_end] s[blank_start]ystem[blank_end] (MEOS)
Antworten
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Cytosol
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cellular
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Alcohol
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Adenine
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Dehydrogenase
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Deoxygenated
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Dehydrator
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Microsomal
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Marcoscopic
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oxidizing
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oxidation reaction
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system
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series
Frage 9
Frage
Which pathway is used for beaking down small amounts of alcohol?
Antworten
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Cytosol Alcohol Dehydrogenase
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Microsomal Ethanol-oxidizing system
Frage 10
Frage
Which pathway is important for breaking down large amounts of alcohol?
Antworten
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Microsonmal Ethanol-Oxidizing System
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Alcohol dehyrogenase
Frage 11
Frage
What can alcohol be metabolized to in the colon?
Antworten
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ethanol
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acetaldehyde
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starch
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dangerous bacteria
Frage 12
Frage
What is the alcohol metabolized by in the colon?
Antworten
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Colon Bacterial ADH
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Bacteria
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amalase
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MEOS
Frage 13
Frage
What is acetaldehyde?
Antworten
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a toxic compound
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a non-toxic compount
Frage 14
Frage
What is one major effect of low doses of alcohol?
Antworten
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slowing the citric cycle
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use of MEOS
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chance of alcoholism
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stomach issues
Frage 15
Frage
*** what is alcohol dehydrogenase?
Antworten
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a family of isoenzymes
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cool
Frage 16
Frage
Which ADH has the highest specificity for ethanol?
Antworten
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class 1 ADHs
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class 2 ADHs
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class 4 ADHs
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they're all equal
Frage 17
Frage
How many genes are there for class 1 ADH?
Antworten
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1
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2
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3
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4
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5
Frage 18
Frage
What do the genes for class 1 ADH exist as?
Antworten
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allelic variants
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polymorphisms
Frage 19
Frage
which ADH class is high in the liver?
Antworten
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1
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2
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3
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4
Frage 20
Frage
what ADH class can be found in GIT?
Antworten
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1
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2
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3
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4
Frage 21
Frage
which of these two are functional polymorphisms
Antworten
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ADH 1A and ADH 1C
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ADH 2A and ADH 1C
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ADH 1X and ADH X
Frage 22
Frage
***what can partially account for observed differences in ethanol elimination rates among individuals or population?
Antworten
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functional polymorphisms
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eating habits
Frage 23
Frage
Possession of which allele is associated with decreased susceptibility to alcoholism?
Antworten
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ADH 1B*2
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ADH 1B*3
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ADH 1A*2
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ADH 1A*3
Frage 24
Frage
What does ADH1B*2 code for?
Antworten
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a relatively fast ADH
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a relative slow ADH
Frage 25
Frage
ALDH = A[blank_start]cetaldehyde[blank_end] D[blank_start]ehydrogenase[blank_end]
Antworten
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cetaldehyde
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ehydrogenase
Frage 26
Frage
What type of ALDH is cytosolic?
Antworten
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ALDH 1
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ALDH 2
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ALDH 3
Frage 27
Frage
What does accumulation of acetylaldehyde cause?
Antworten
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nausea
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vomiting
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chest pains
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hunger
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thirst
Frage 28
Frage
What can an ALDH inhibitor be used for?
Antworten
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Drug treatment for alcoholism
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cure for thirst
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it can't be used for anything, it's toxic
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liver repair
Frage 29
Frage
what does metabolism of acetate require?
Antworten
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activation to acetyl CoA
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deactivation from acetyl CoA
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reduction of Fatty Acids
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removal of a phosphate group
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