Frage 1
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Flow rate is how much [blank_start]urine[blank_end] you are [blank_start]producing[blank_end] per unit of [blank_start]time[blank_end]
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urine
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urea
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time
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distance
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producing
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consuming
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voiding
Frage 2
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GFR is the amount of [blank_start]fluid[blank_end] going into [blank_start]bowmans capsule[blank_end] per unit of [blank_start]time[blank_end]
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fluid
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blood
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bowmans capsule
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the nephron
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time
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flow
Frage 3
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what is normal glomerular flow rate?
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100-130ml/min
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500-600ml/min
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200-300ml/min
Frage 4
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Filtered load is the same as
Frage 5
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[blank_start]Filtered load[blank_end] / tubular load is the [blank_start]amount of a specific solute[blank_end] ([blank_start]electrolyte, glucose or amino acid[blank_end]) entering [blank_start]bowman's capsule[blank_end].
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Filtered load
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amount of a specific solute
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electrolyte, glucose or amino acid
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electrolyte, carbohydrate or protein
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salt
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bowman's capsule
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the kidney
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the nephron
Frage 6
Frage
Filtered Load can be calculated from [blank_start]GFR[blank_end] and [blank_start]Plasma concentration of solute[blank_end]
Frage 7
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freely filtered
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not metabolised
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not reabsorbed
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not secreted
Frage 8
Frage
Inulin
The excretion rate = ...
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excretion rate
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filtration rate
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absorption rate
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consumption rate
Frage 9
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freely filtered
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not metabolised
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not reabsorbed
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freely secreted
Frage 10
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What does clearance less than 125ml/min indicate?
Frage 11
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What does clearance more than 125ml/min indicate?
Frage 12
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What can be used to experimentally measure GFR?
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Inulin
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glucose
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PAH
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calcium
Frage 13
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What is elevated Pcr an indicator of?
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reduced GFR
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increased GFR
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non changing GFR
Frage 14
Antworten
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appearance of solute in urine before you reach the overall Transport maximum of the kidney
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the plasma concentration at which a substance begins to appear in the urine
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the tiny amount of solute appearing in urine when a single nephron reaches its maximum
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the total transport maximum through out all of the nephrons in the kidney
Frage 15
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what is transport maximum?
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the total transport maximum through out all of the nephrons in the kidney
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The point at which an amount of solute appears in urine when nephrons reaches its maximum
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the plasma concentration at which a substance begins to appear in the urine
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appearance of solute in urine before you reach the overall threshold of the kidney
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The maximum rate of the solute shuttling done by transporters
Frage 16
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How can renal function be measured?
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imaging techniques
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renal clearance
Frage 17
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The [blank_start]renal[blank_end] clearance value of a certain substance is the [blank_start]volume of plasma[blank_end] which is [blank_start]cleared of this substance[blank_end] by the kidney into urine [blank_start]/ min[blank_end].
Frage 18
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What do we need to know to measure renal clearance?
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volume of urine / min
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concentration of the substance mg/ml urine
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concentration of the substance mg/ml plasma
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concentration of the substance mg/ml blood
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volume of substrate / min
Frage 19
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What properties does a substance used in a plasma clearance test have?
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does not enter RBCs
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does not affect normal renal function
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should not be metabolized by the kidney
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should be easily measured in plasma & urine
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should be non toxic
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should be easy to consume
Frage 20
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What do we use renal clearance for?
Frage 21
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What is the rate-limiting step in the tubular transport of glucose?
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Na-glucose symport
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glucose uniporter
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glucose reabsorption
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ca- glucose symport
Frage 22
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The plasma leaving the kidney through the renal veins lacks .....
Frage 23
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What is creatinine?
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the end product of creatine metabolism
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the end product of creatinine metabolism
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a phospholipid
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dumped into the blood by smooth muscle
Frage 24
Frage
Creatinine is continuously dumped into the blood by....
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smooth muscle
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skeletal muscle
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cardiac muscle
Frage 25
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the rate of creatinine appearance in blood is proportional to a person's ....
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muscle mass
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fat mass
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urine excretion
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blood
Frage 26
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freely filtered
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not reabsorbed
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reabsorbed
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not freely filtered
Frage 27
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how much creatinine is secreted by the proximal tubule?
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10-20%
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40-50%
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70-80%
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85-100%
Frage 28
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There is a ______________ between plasma creatinine concentration and GFR.
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inverse correlation
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indirect correlation
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direct relationship
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direct correlation
Frage 29
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What is the most common method used for routine GFR assessments?
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creatinine clearance
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inulin clearance
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PAH clearance
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Plasma clearance
Frage 30
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If there are more solutes present than can be transported, the solutes will end up...
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In urine
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Reabsorbed
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In the blood stream
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Excreted in faeces
Frage 31
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Renal clearance is comparison of [blank_start]filtration[blank_end] rate of a substance to the rate of it's appearance in the [blank_start]urine[blank_end] i.e. Amount [blank_start]filtered[blank_end] vs amount [blank_start]excreted[blank_end]. It gives info on [blank_start]re-absorption[blank_end] and [blank_start]secretion[blank_end]
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filtration
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urine
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urea
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blood
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filtered
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excreted
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re-absorption
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secretion
Frage 32
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What percentage of clearance?
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A= ?% B=?% C=0% D=100%
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A= 0% B=50% C=0% D=100%
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A= 100% B=0% C=?% D=?%
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A= 25% B=25% C=25% D=25%
Frage 33
Frage
Renal clearance principle is based on the principle of [blank_start]mass[blank_end] [blank_start]balance[blank_end]. Input of X is [blank_start]equal to[blank_end] output of X
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mass
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balance
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equal to
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more than
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less than
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pressure
Frage 34
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fill in the formula
Frage 35
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Tm for PAH secretory mechanism ~80mg/ml.
PPAH [blank_start]<[blank_end] 80mg/ml = good estimation of RPF
PPAH [blank_start]>[blank_end] 80mg/ml = poor estimation of RPF
At [blank_start]low[blank_end] [blank_start]PPAH[blank_end]: [blank_start]PAH[blank_end] clearance [blank_start]=[blank_end] RPF
Frage 36
Frage
Clearance units are [blank_start]volume[blank_end] per [blank_start]time[blank_end]
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volume
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time
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distance
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meter
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second
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pressure
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flow
Frage 37
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Clearance is not the amount of the [blank_start]substance removed[blank_end] but instead the volume of [blank_start]plasma from which it was removed[blank_end].
Frage 38
Frage
PAH is an abbreviation of ...
Antworten
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para-aminohippurate
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pilo-acidic-hormone
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pregacilohinutrate
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primary acid hilute