Infectious Diseases Final MCQs- 5th Year PMU

Beschreibung

Infectious Diseases Final MCQs- 5th Year PMU
Med Student
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Zusammenfassung der Ressource

Frage 1

Frage
The specific CNS complication of Chickenpox is
Antworten
  • cerebellitis
  • meningitis serosa
  • polyradiculoneuritis - Guillain-Barre

Frage 2

Frage
Treatment of cerebral oedema includes
Antworten
  • Diuretics – spironolactone
  • Diuretics – mannitol, furanthril
  • Non-steroidal anti-inflammatory drugs

Frage 3

Frage
Common presentations of AIDS are
Antworten
  • prolong morning low grade fever, weight loss, diarrhea
  • hyperpyrexia with profuse sweating, dehydration with metabolic changes
  • bulimia, hyperactivity, psychomotor agitation

Frage 4

Frage
Which meningitis is characterized by the following CSF findings – lymphocytic pleocytosis, normal or slightly elevated protein and normal glucose level?
Antworten
  • Viral
  • Purulent
  • Tuberculous

Frage 5

Frage
The rash in Scarlet fever is
Antworten
  • maculo-papules, vesicular, different stages at the same time
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribed

Frage 6

Frage
Typical for Diptheria are
Antworten
  • dense, dirty gray, hard deposits on the tonsils
  • whitish deposits on the tonsils and buccal mucosa, easily removable
  • the disease is widespread in Bulgaria

Frage 7

Frage
The most common clinical manifestation of Salmonellosis is
Antworten
  • sepsis
  • cholecystitis
  • gastroenteritis

Frage 8

Frage
Which is the antibiotic of choice of for Mediterranean spotted fever
Antworten
  • Gentamycin
  • Doxycycline
  • Ceftriaxone

Frage 9

Frage
Poliomyelitis is characterised by
Antworten
  • flaccid asymmetric, proximal paralysis
  • flaccid symmetric, proximal paralysis
  • full recovery of the affected limb

Frage 10

Frage
Typical for clinical presentation of Cholera is
Antworten
  • rigor and high fever
  • ‘rice water’ stools
  • persistent vomiting, severe stomach pain

Frage 11

Frage
The agent of which disease has teratogenic effect?
Antworten
  • Rubella
  • Scarlet fever
  • Measles

Frage 12

Frage
The main factor for chronicity in HBV infection is
Antworten
  • age
  • innate immunity
  • gender

Frage 13

Frage
The diarrheal syndrome in shigellosis is characterised with
Antworten
  • large amount of watery stools + abdominal pain
  • sparse, bloody mucoid stools + tenesmi
  • voluminous liquid, ” rice water” type stools

Frage 14

Frage
Hepatitis with the most severe course with possibility of acute liver failure is
Antworten
  • acute hepatitis C
  • acute hepatitis B+ hepatitis D
  • viral hepatitis E
  • viral hepatitis A

Frage 15

Frage
Which infection is vaccine preventable
Antworten
  • Salmonella
  • Measles
  • Scarlet fever

Frage 16

Frage
Hypopotassemia may be suspected in a patient with
Antworten
  • enhanced motility and spastic colon
  • intestinal paresis and bloated abdomen
  • generalized seizures

Frage 17

Frage
Empirical therapy for bacterial meningitis includes
Antworten
  • 3rd generation Cephalosporins + Vancomycin
  • Penicillin + Metronidazole
  • 3rd generation Cephalosporins + Clindamycin

Frage 18

Frage
Measles rash appears
Antworten
  • 24 h after onset of the disease
  • the disease begins with it
  • on 3-5-the day of disease onset

Frage 19

Frage
The stools in cholera resemble
Antworten
  • rice water
  • sputum with mucus, blood and pus
  • raspberry jelly

Frage 20

Frage
The most common causative agents of purulent meningitis are
Antworten
  • S.pneumoniae, N. meningitidis, H. influenzae
  • S.pneumoniae, Staph.aureus, Myc. tuberculosis
  • N meningitidis, L. monocytogenes, St. epidermidis

Frage 21

Frage
The rash of Chicken pox is
Antworten
  • maculo-papules, vesicular, different stages at the same time
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribed

Frage 22

Frage
Who is NOT at risk for severe Chickenpox
Antworten
  • persons with cellular immunodeficiency
  • pregnant
  • children aged 2-6

Frage 23

Frage
The earliest laboratory test for confirmation of acute hepatitis C is
Antworten
  • Anti-HCV by ELISA
  • HCV RNA by PCR
  • HCV Ag by ELISA

Frage 24

Frage
Pregnant in the 1st trimester has discrete macular rash and negative serological test (ELISA) for Rubella. What is the next step?
Antworten
  • Therapeutic abortion
  • Ribavirin therapy
  • Repeating the test after 3 weeks

Frage 25

Frage
Shigellosis is likely to present with seizures in
Antworten
  • elderly people
  • children under the age of 3 years
  • such onset is unlikely

Frage 26

Frage
Which test is best to confirm EBV as causative agent of infectious mononucleosis
Antworten
  • detection of heterophile antibodies
  • detection of specific antibodies to EBV
  • detection of nucleic acid of EBV in the blood

Frage 27

Frage
Raspberry tongue is typical for
Antworten
  • Scarlet fever
  • Measles
  • Chickenpox

Frage 28

Frage
The most common neoplasm in HIV infection is
Antworten
  • Kaposki‘s sarcoma
  • Pulmonary carcinoma
  • Melanoma

Frage 29

Frage
The aminotransferases (ALT and AST) in acute viral hepatitis are
Antworten
  • Normal
  • 100 E/L
  • > 1000 E/l

Frage 30

Frage
Etiological treatment of choice in cholera is
Antworten
  • penicillin
  • cephalosporin 4-th generation
  • tetracycline

Frage 31

Frage
Antibiotic of choice for the treatment of Scarlet fever is
Antworten
  • tetracycline
  • penicillin / beta-lactam
  • gentamicin

Frage 32

Frage
Meningeal irritation includes
Antworten
  • nuchal rigidity, hyperesthesia
  • diminished tendon reflexes
  • altered mental status

Frage 33

Frage
Route of transmission in Lyme disease is
Antworten
  • via tick bite
  • via drinking unpasteurized milk
  • via mosquito bites

Frage 34

Frage
The most common causative agent of pneumonia in AIDS patients is
Antworten
  • Mycoplasma pneumoniae
  • Pneumocystis jiroveci (carinii)
  • Hantavirus

Frage 35

Frage
Typical clinical manifestation of tetanus is
Antworten
  • confusion
  • periodic muscle rigidity
  • permanent muscle rigidity and periodic seizures

Frage 36

Frage
Antibiotic of choice for treatment of Erythema migrans is
Antworten
  • Cefrtiaxone
  • Doxycycline
  • Gentamycine

Frage 37

Frage
Measles rash
Antworten
  • appears after 24 h after the disease onset
  • the disease starts with it
  • appears on 3-5th day of disease onset

Frage 38

Frage
At risk of acute viral hepatitis C are
Antworten
  • intravenous drug abusers
  • newborns in poor sanitary conditions
  • travellers to tropical countries

Frage 39

Frage
The rash of meningococcemia is
Antworten
  • hemorrhagic necrotic, localized predominantly on the lower limbs and buttocks
  • vesicular, diffuse
  • vesicular, highly pruritic

Frage 40

Frage
Initial treatment of infectious diarrhea includes
Antworten
  • rehydration
  • antibiotic
  • correction of ↓K

Frage 41

Frage
On suspicion of acute viral hepatitis the minimum laboratory TESTS are
Antworten
  • alkaline phosphate, gamma glutamyl transferase
  • urine (bile pigments), serum (ALT and AST, bilirubin)
  • complete blood count, electrolytes, acid-base metabolism

Frage 42

Frage
The evolution of Chickenpox rash is
Antworten
  • macula – papule - vesicle - crust
  • macula- papule - brown pigmentation
  • petechiae- ecchymosis- suffusion

Frage 43

Frage
The main factor for chronicity in HBV infection is
Antworten
  • age
  • innate immunity
  • gender

Frage 44

Frage
The mainstay of diphtheria treatment is
Antworten
  • antibiotics
  • antitoxin serum
  • corticosteroids

Frage 45

Frage
Which infection is vaccine-preventable
Antworten
  • Measles
  • Scarlet fever
  • Lyme borreliosis

Frage 46

Frage
Koplik spots are pathognomonic sign for
Antworten
  • Scarlet fever
  • Measles
  • Rubella

Frage 47

Frage
Jaundice as a clinical manifestation of acute viral hepatitis C is seen
Antworten
  • in a few patients
  • in the majority of patients
  • in about half of the cases

Frage 48

Frage
Laboratory minimum for suspected viral hepatitis is
Antworten
  • urine (bile pigments), serum (ALT and AST, bilirubin)
  • CBC, electrolytes, acid-base balance
  • abdominal ultrasound

Frage 49

Frage
Meningeal irritation, prolonged clouding consciousness and focal neurological findings are common in
Antworten
  • meningoencephalitis
  • encephalitis
  • meningitis

Frage 50

Frage
The incubation period in Shigellosis is
Antworten
  • 2 weeks
  • 1-7 days
  • 4-6 hours

Frage 51

Frage
What type of toxin is released by Salmonella bacteria on cell lysis
Antworten
  • endotoxin
  • neurotoxin
  • enterotoxin

Frage 52

Frage
Which of the following agents causes hemolytic-uremic syndrome
Antworten
  • enterohemorrhagic E.coli
  • enteroinvasive E.coli
  • pathogenic E.coli

Frage 53

Frage
The agent of which disease has teratogenic effect?
Antworten
  • Rubella
  • Scarlet fever
  • Measles

Frage 54

Frage
Which of the following statements regarding enteroviruses as causative agents of aseptic meningitis are NOT TRUE?
Antworten
  • Enteroviruses account for up to 80% of cases of viral meningitis.in children
  • the clinical presentation in children is milder than in adults
  • lymphocytes are predominant in the first 24 hours, later neutrophils prevail

Frage 55

Frage
Which type of immunity is impaired in HIV infection?
Antworten
  • humoral
  • cell mediated
  • innate

Frage 56

Frage
Viral hepatitis A is transmitted via
Antworten
  • fecal-oral mechanism
  • parenteral mechanism
  • sexual mechanism

Frage 57

Frage
The most common causative agent of of Infectious mononucleosis is
Antworten
  • Epstein-Barr virus
  • Cytomegalovirus
  • HIV

Frage 58

Frage
The main route of transmission of hepatitis C virus is
Antworten
  • fecal-oral
  • intravenous usage
  • sexual

Frage 59

Frage
The rash in Scarlet fever is ???
Antworten
  • maculo-papules, vesicular, fast evolution of stages
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribed

Frage 60

Frage
The mental status in tetanus is
Antworten
  • blurred
  • alert
  • hallucinations are typical

Frage 61

Frage
Typical Measles rash is
Antworten
  • maculo-papular rash appearing on the first day of the disease
  • maculo-papular rash, confluent, appears on the 4-5 the day
  • discrete maculo-papular rash fades after 3 days

Frage 62

Frage
Which type of meningitis is characterized by the following CSF findings – lymphocytic pleocytosis, elevated protein and decreased glucose level
Antworten
  • viral
  • purulent
  • tuberculous

Frage 63

Frage
Which of the following conditions are NOT AIDS-defining illness?
Antworten
  • Herpes zoster
  • Kaposki’s sarcoma
  • Esophageal candidiasis

Frage 64

Frage
Cholera initially presents with
Antworten
  • chills and high fever
  • diarrhea ” rice water” type
  • intractable vomiting

Frage 65

Frage
Which of the following microorganisms is associated with diarrhoea after antibiotic therapy or severe operations
Antworten
  • Cl. difficile
  • Salmonella
  • E.coli

Frage 66

Frage
Diarrheal syndrome in shigellosis is characterised by
Antworten
  • large amount of watery stools + abdominal pain
  • sparse, bloody mucoid stools + tenesmi
  • voluminous liquid, ” rice water” type stools

Frage 67

Frage
A pregnant woman in first trimester had contact with a sick child, suspected to have rubella. How could you manage her
Antworten
  • to clarify if the child has Rubella
  • to recommend abortion on medical grounds
  • to determine her immunity by serology

Frage 68

Frage
The most common presentation of Lyme borreliosis is
Antworten
  • erythema migrans
  • arthritis
  • neuritis

Frage 69

Frage
The most common initial complaints in acute viral hepatitis are
Antworten
  • fatigue, anorexia, nausea, loss of appetite
  • severe abdominal pain radiating to the shoulders and vomiting
  • fever and diarrhoea

Frage 70

Frage
First choice antibiotic for treatment of pertussis is
Antworten
  • ceftriaxone
  • macrolides
  • amikacin

Frage 71

Frage
Empirical treatment on suspicion of bacterial meningitis includes
Antworten
  • 3rd generation Cephalosporins + Vancomycin
  • Penicillin + Metronidazole
  • 3rd generation Cephalosporins + Clindamycin

Frage 72

Frage
Thick pseudomembrans, spreading across the pharyngeal mucosa and bleeding while dislodging, are characteristic for
Antworten
  • mononucleosis
  • diphtheria
  • strepto pharyngitis

Frage 73

Frage
Pustula maligna is typical for
Antworten
  • Anthrax
  • Mediterranean spotted fever
  • Tularemia

Frage 74

Frage
Anthrax infection results from
Antworten
  • exposure to cattle and goats
  • tick bite
  • mosquito bite

Frage 75

Frage
Acute hepatitis C becomes chronic in
Antworten
  • 30-80%
  • < 2%
  • >90%

Frage 76

Frage
The stages in the course of HIV/AIDS infection are
Antworten
  • early HIV infection, latency period, AIDS
  • catarrhal period , rash period , convalescent period
  • initial intoxication period, period of generalized lymphnodulomegaly, period of hepatosplenomegaly

Frage 77

Frage
Serological markers of acute viral hepatitis B are
Antworten
  • HBsAg (+) and anti HBc IgM (+)
  • HBsAg (+) and anti HBc total (+)
  • anti HBsAg (+) and anti HAV IgM (+)

Frage 78

Frage
Arthralgia in acute viral hepatitis presents with
Antworten
  • joint pain without swelling and redness
  • swelling, redness and forced position
  • swelling without pain and redness

Frage 79

Frage
Tache noire (black spot) at the site of the tick bite represents
Antworten
  • painless ulcer covered with black (necrotic) crust
  • painless oval or round pink or red skin plaque> 5 cm
  • painful hot red plaque with raised edges

Frage 80

Frage
Which of the following findings IS NOT characteristic of infant meningitis?
Antworten
  • bulging fontanelle, Lessage sign
  • distended abdomen
  • crie encephalique

Frage 81

Frage
The screening test for HIV infection is
Antworten
  • anti HIV (ELISA)
  • viral RNA (PCR)
  • anti HIV (immunoblot)

Frage 82

Frage
The rash in Mediterranean spotted fever is
Antworten
  • maculopapular
  • vesicular
  • erythematous

Frage 83

Frage
Which diseases in not vaccine preventable
Antworten
  • Lyme borreliosis
  • Poliomyelitis
  • Measles

Frage 84

Frage
The most common electrolyte abnormalities in patients with diarrhea are
Antworten
  • hyponatremia and hypokaliemia
  • hypercalcemia and hyperkaliemia
  • hypernatriemia and hyperchloremia

Frage 85

Frage
Acyclovir is recommended to which of following cases
Antworten
  • Chicken pox - mandatory
  • Chicken pox in immunocompromised patients
  • Kaposi sarcoma

Frage 86

Frage
Which of the following statements regarding leptospirosis IS NOT true”
Antworten
  • Leptospirosis is a biphasic illness with multiorgan involvement
  • Gentamycin is the antibiotic of choice
  • Infection is acquired during walking or bathing in rivers

Frage 87

Frage
At risk for development of Herpes Zoster are
Antworten
  • adolescents (aged 11-19 years)
  • patients with HIV infection
  • newborns

Frage 88

Frage
Characteristic clinical manifestation of enteroviral infections is
Antworten
  • Herpagina
  • Gingivostomatitis
  • Exudative pharyngitis

Frage 89

Frage
The rash in Scarlet fever is
Antworten
  • small maculopapules predominantly in the axilar and inguinal regions
  • vesicular rash, which most commonly affects a thoracic dermatome
  • pustular, at the same stage of development, deep-seated, firm, round, well-circumscribe

Frage 90

Frage
Inflammatory diarrhea is commonly caused by
Antworten
  • Shigella sp., Campylobacter jejuni, Cl. difficile
  • Viruses, enterotoxigenic E. coli
  • S. aureus, B. cereus, most Salmonella sp.

Frage 91

Frage
When is ART warranted
Antworten
  • For all HIV positive regardless of CD4 count
  • CD4<200 cells/µL
  • CD4< 350 cells/µL

Frage 92

Frage
In the case of infectious mononucleosis-like symptoms, it is important to consider
Antworten
  • primary HIV infection
  • neoplasms
  • syphilis
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