222007
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Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312
vor mehr als 11 Jahre
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Frage 1
Frage
Which type of protein is conjugated?
Antworten
-
One that contains only amino acid residues
-
One that contains prosthetic groups
-
One that is bound to a membrane
Frage 2
Frage
Which of the following means a protein with two identical subunits?
Antworten
-
Heteromultimer
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Homomonomer
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Homomultimer
Frage 3
Frage
Which of the following proteins types tend to have various roles, as opposed to a single, defined one?
Antworten
-
Fibrous
-
Globular
-
Membrane
Frage 4
Frage
Which of the following tend not to be water soluble?
Antworten
-
Fibrous
-
Globular
-
Membrane spanning
Frage 5
Frage
What secondary structures tend to make up fibrous proteins?
Antworten
-
Long strands
-
Long sheets
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Short strands
Frage 6
Frage
What is specific about the membrane spanning part of membrane proteins?
Antworten
-
They are hydrophobic
-
They are hydrophillic
Frage 7
Frage
Define 'Domain' in reference to protein structure
Antworten
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Independent folding units of the tertiary structure that have independent functions
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Independent folding units of tertiary structure that have related functions
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Dependent folding units of secondary structure that have relation functions
-
Dependent folding units of tertiary structure that have related functions
Frage 8
Frage
Define subunit
Antworten
-
Independent structures in a quaternary structure
-
Independent structures in a tertiary structure
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Dependent subunits in a quaternary structure
Frage 9
Frage
What can be the result of a single amino acid mutation in collagen?
Antworten
-
Osteoarthritis
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Osteogenesis imperfecta
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Osteocalcification
Frage 10
Frage
What is Resonance (as pertaining to protein structure)?
Antworten
-
Where bond pairs cannot be described as a single Lewis Diagram
-
Where two atoms in separate molecules cause each other to vibrate
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Where two atoms in separate molecules are more likely to bond to each other than to another atom
Frage 11
Frage
Which is the psi bond?
Antworten
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Between the carbonyl carbon and the alpha carbon
-
Between the alpha carbon and the amide group
-
Between the alpha carbon and the R group
Frage 12
Frage
Which is the phi bond?
Antworten
-
Between the alpha carbon and the amide group
-
Between the alpha carbon and the carbonyl carbon
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Between the alpha carbon and the R group
Frage 13
Frage
What is Steric clashing?
Antworten
-
Where the charge of an atom prevents it from being close to another
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Where the electron arrangement of an atom prevents it from being close to another
-
Where the size of an atom prevents it from being close to another
Frage 14
Frage
Why is a peptide bond planar?
Antworten
-
It has a double bond like structure
-
It's electrons clash with that of the psi bond
-
It's electrons clash with the phi bond
Frage 15
Frage
How many residues per turn in an alpha helix?
Antworten
-
3.4
-
3.5
-
3.6
Frage 16
Frage
How much does an alpha helix rise per aa?
Antworten
-
1.5 angstroms
-
1.6 angstroms
-
1.7 angstroms
Frage 17
Frage
Alpha helices are stabilised by hydrogen bonding with what groups?
Antworten
-
Carbonyl oxygen 4 amino acids away
-
Carbonyl oxygen 6 amino acids away
-
Carbonyl oxygen 8 amino acids away
Frage 18
Frage
The stabilising effect of the hydrogen bonds makes a loop of how many atoms?
Antworten
-
12
-
13
-
14
Frage 19
Frage
Which of the following destabilize an alpha helix?
Antworten
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Glycine
-
Proline
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Leucine
-
Glutamic acid
Frage 20
Frage
Beta sheets rise by 3.47A per residue in anti-parallel sheets
Antworten
- True
- False
Frage 21
Frage
In parallel sheets, there is a rise of .... per residue
Antworten
-
3.25A
-
4.25A
-
2.25A
Frage 22
Frage
3 residues per turn of the strand are pictured as a helix
Antworten
- True
- False
Frage 23
Frage
Anti-parallel strands are _ stable than parallel ones
Antworten
-
More
-
Less
Frage 24
Frage
Side chains all point the same way (in the plane of the sheet)
Antworten
- True
- False
Frage 25
Frage
What is the role of loops?
Antworten
-
Connecting alpha and beta sheets
-
Connecting alpha helices and alpha helices
-
Connecting beta sheets and beta sheets
Frage 26
Frage
Loops contain mostly hydrophillic residues & are found on the protein surface
Antworten
- True
- False
Frage 27
Frage
What is the role of beta turns?
Antworten
-
To allow beta sheets to reverse direction
-
To connect beta sheets together
-
To link protein subunits together
Frage 28
Frage
What two amino acids cannot be contained within a beta sheet?
Antworten
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Proline
-
Argenine
-
Glycine
-
Valine
Frage 29
Frage
Beta turns link the oxygen of the carbonyl group and the hydrogen of the nitrile group 4 residues away
Image:
Beta_Turns (image/jpg)
Antworten
- True
- False
Frage 30
Frage
Levinthals Paradox- if a protein folded by trying each fold in a sequence, it would take an impossibly long time to fold correctly. Therefore, protein folding cannot be random or sequential
Antworten
- True
- False
Frage 31
Antworten
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The energy change as proteins fold
-
Gibbs free energy
-
Entropy change
Frage 32
Frage
Why are the internal interactions of protein folding unfavorable?
Antworten
-
It decreases entropy
-
They're hydrophobic in a hydrophillic environment
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They prevent the protein from folding correctly
Frage 33
Frage
Non-covalent and hydrophobic effects (which effects free water) decrease enthalpy
Antworten
- True
- False
Frage 34
Frage
Change in energy during folding = Internal interactions - (Hydrophobic effect + conformational entropy)
Antworten
- True
- False
Frage 35
Frage
Proteins fold towards configurations with the...
Antworten
-
lowest energy
-
Highest energy
-
Easiest energy to reach (energy closest to that of unfolded protein)
Frage 36
Frage
What can slow the progress of protein folding?
Antworten
-
A local low energy minimum
-
A local high energy minimum
Frage 37
Frage
What is nucleation?
Antworten
-
Reversible secondary structure formation
-
Reversible tertiary structure formation
-
Reversible quaternary structure formation
Frage 38
Frage
Which of the following happens after nucleation?
Antworten
-
The secondary structure aggregation forms a molten globular intermediate
-
Domains adjust to the lowest energy form
Frage 39
Frage
The protein is capable of conformational change after forming
Antworten
- True
- False
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