Frage 1
Frage
What is true about sarcomeres?
Antworten
-
Extend from M to M line
-
The major protein of Z line sarcomeres is myosin
-
ContainsZline+1⁄2 Iband+Aband+1⁄2Iband+Zline
-
The major protein of the Z line of sacromere is creatines kinase
Frage 2
Frage
What is true about skeletal muscle?
Antworten
-
T-tubuls are absent
-
Caveolas and gap junctions can be occasionally present
-
Actin-myosin binding is triggered by interaction of Ca2+ with troponin subunit C
-
Concentration triggered at motor end plate
-
Formed by structures called fibers
-
Skeletal muscle fibers are innervated by muscle neurons
Frage 3
Frage
What is true about perimysium?
Antworten
-
It does not contain any blood vessels
-
It surrounds every single muscle fiber
-
It surrounds the whole muscle
-
It contains blood vessels
-
It surrounds a bundle of fibers
Frage 4
Frage
Which statement about skeletal muscle are correct?
Antworten
-
Regeneration of skeletal muscles directly depends on amount of calcium ions
-
There are no sarcomeres in fibers
-
Skeletal muscle fibers are innervated by motor neurons
-
Are formed by structures called fibers
Frage 5
Frage
Which pair is correctly paired?
Antworten
-
Simple cuboidal – lining ducts of most glands
-
Transitional – urinary bladder
-
Simple squamous – epidermis of skin
Frage 6
Frage
Which statement regarding nodal cilia is true?
Antworten
-
Are associated with gastrulation
-
Are found in the embryo
-
Are arranged into 9 + 10 pattern
-
Are associated with rotational movement
Frage 7
Frage
In which type of junction occluding and claudin are characteristic and prominent?
Frage 8
Frage
What is true about mesenchyme?
Antworten
-
Is called 4th germ layer
-
Is located between the mesenchyme and endoderm
-
Is located in mesoderm
-
Is one of three germ layers
-
Is located between the ectoderm and endoderm
-
Is derived from mesoderm
Frage 9
Frage
What is true about mesoderm?
Antworten
-
Is one of the three germ layers
-
Is derived from mesenchyme
-
Is called 4th germ layer
-
Appears only during the prenatal life
-
Is located between the mesenchyme and endoderm
-
Is located above the ectoderm
Frage 10
Frage
What is true about so somitogenesis?
Antworten
-
It happens before the initiation of neurolation
-
This is the process of segmentation of the paraxial mesoderm
-
Is regulated by the so-called segmentation and wave model
-
It occurs after the intitation of neurulation
-
It starts at the beginning of the 3rd week of prenatal life
-
It begins at the beginning of the 3rd month of prenatal life
Frage 11
Frage
Which statement regarding apical surface`s modification is correct?
Antworten
-
Tight junction
-
Glycocalix
-
Goblet cell
-
Villus
Frage 12
Frage
Which of GAGs is/are characteristic for cartilage?
Antworten
-
Keratin sulfate
-
Osteonectin
-
Hyaluronic acid
-
Dermatologist sulfate
Frage 13
Frage
What is true sclerotome?
Antworten
-
Contains only epithelial like cells
-
Is derived from ventro-medial somite cells
-
Scelerotome gives rise to mesoderm
-
Contains secondary mesenchyme cells
Frage 14
Frage
What is true about somites?
Antworten
-
They are blocks (segment) of the paraxial mesoderm
-
They are symmetrical structures
-
They are blocks (segment) of the lateral mesoderm
-
They are blocks (segment) of the visceral mesoderm
Frage 15
Frage
Which sentence/sentences is/are true?
Antworten
-
Osteoclasts possess of the receptor for calcitonin
-
Inner fibrous layer of perichondrium contains chondrogenic cells
-
The precursors of osteoclasts are monocytes
-
Outer fibrous layer of perichondrium contains chondrogenic cells
Frage 16
Frage
Which feature regarding hyaline cartilage is correct?
Antworten
-
Chondrocytes are grouped in isogenic groups
-
It is covered by perichondrium
-
Perichondrium is composed of two layers
-
Hyaline cartilage is highly vascularized
Frage 17
Frage
Which of the statements about woven bone is/are true?
Antworten
-
Physiologically can be found in compact mature bone
-
Can be found in insertions of some tendon
-
In adult present in place of fracture repair
-
Possess lamellae
Frage 18
Frage
Which of the phrase/phrases concerning the perichondrium is/are true?
Antworten
-
Is formed by collagen type II
-
Is responsible for appositional growth of cartilage
-
Acts protective for cartilage
-
Contains Sharpey fibers
Frage 19
Frage
Which cells of connective tissue promote the allergenic reactions?
Antworten
-
Fibrocytes
-
Histiocytes
-
Fat cells
-
Mast cells
Frage 20
Frage
Which statement regarding connective tissue (CT) proper is true?
Antworten
-
Is divided into loose and dense CTs
-
Collagen contains unusual amino acids desmosine and indodesmosine
-
Chondroblasts are main population of cells in the tissue
-
Transient cells of connective tissue are e.g fibroblasts
Frage 21
Frage
Which statement regarding adipose tissue is true?
Antworten
-
There are two types, white uniocular and brown multilocular
-
Multiocular is rich in the human adult
-
Leptin is secretory product of white adipocytes
-
Brown adipose tissue changes into yellow one
Frage 22
Frage
What is the characteristic function of mast cells?
Antworten
-
The surface contain receptor for IgE
-
Influence permeability of blood vessels
-
Participate in process of wound healing
-
Storing of chemical mediators in granules
Frage 23
Frage
What type of tissue is a tendon?
Frage 24
Frage
Which statement about holocrine glands is true?
Antworten
-
Its example is sebaceous gland
-
The cells are often surrounded by myoepithelial cells
-
It’s example is mammary gland
-
The product of the cell is released with its apical part
Frage 25
Frage
Which of the sentence/s about cartilage is/are true?
Antworten
-
Is avascular (without blood vessels) tissue
-
Ventral ends of the ribs are formed by hyaline cartilage
-
Ventral ends of the ribs are formed by fibrocartilage
-
Chondrogenic cells are the stem cells for chondroblasts
-
Epiphyseal plates are the hyaline cartilage structures needed for long bones growth
-
Hyaline cartilage form the temporal skeleton
-
Is well vascularized
Frage 26
Frage
Is it true that osteogenesis?
Antworten
-
Is the bone development process
-
During intramembranous ossification the epiphyseal cartilages are formed
-
It could be said that bony collar formation is a kind of intramembranous ossification
-
Could happen thanks intramembranous ossification
Frage 27
Frage
Which sentence/s is/are true?
Antworten
-
Haversian Canal is located in the periphery of the osteon
-
Inner fibrous layer of perichondrium contains chondrogenic cells
-
The precursors of osteoclasts are monocytes
-
Outer fibrous layer of perichondrium contains chondrogenic cells
Frage 28
Frage
Which of the phrase/s concerning osteoclasts are true?
Antworten
-
Arises from monocytes
-
Produces cathepsin K
-
Pumping protons into resorption cavity of bone
-
Its projections form ruffled border
-
To its differentiation need RANKI
Frage 29
Frage
Which statement regarding connective tissue (CT) proper is true?
Antworten
-
Is divided into loose and dense CTs
-
Fibroblasts can be differentiated into histiocytes
-
Cells of embryonic mesenchymal CT produce type I collagen fibers
Frage 30
Frage
What is the characteristic function of mast cells?
Antworten
-
Influence permeability of blood vessels
-
Their histamine acts as an anticoagulant
-
Synthesis of IgE
-
They can produce elastic fibers
-
The surface contains receptors for IgE
-
Storing chemical mediators in granules
Frage 31
Frage
Which features are characteristic for multilocular adipose tissue?
Frage 32
Frage
Which type of tissue is tendon?
Frage 33
Frage
Which statement regarding synthesis of collagen fibers are correct?
Antworten
-
Hydroxylation of proline and lysine is within extracellular environment
-
Glycosylation of hydroxylysine is within extracellular environment
-
Procollagen is precursor for tropocollagen
-
Hydroxylation of proline and lysine is within intracellular environment
-
Co-factors; O2, Fe, vit. C are needed for the hydroxylation of proline and lysine
Frage 34
Frage
What is true about somites?
Antworten
-
They develop from the cranial towards the caudal region
-
They are blocks (segments) of the paraxial mesoderm
-
None of them disappear
-
They appear between the 20th and 35th day of prenatal life
Frage 35
Frage
What is true about the dermatome?
Antworten
-
Is a structure located closer to the ectoderm in developing embryo
-
It will soon contribute to the development of the skeletal muscles
-
Dermatome progenitors together with cells from the lateral mesoderm will form an epidermis
-
Dermatome cells are differentiated from dermomyotome
-
Is the structure located closer to the neural tube in embryo
-
Dermatome progenitors together with cells from the lateral mesoderm will form a dermis
-
Dermatome cells are differentiated from myotome
Frage 36
Frage
What is true about perimysium?
Antworten
-
It surrounds every single muscle fiber
-
It surrounds the whole muscle
-
It does not contain any blood vessels
-
It contains blood vessels
-
It surrounds a bundle of fibers
Frage 37
Frage
What is true about sarcomeres?
Antworten
-
Contains Z line + 1/2 I band + A band + ½ I band + Z line
-
Are typical for smooth muscle
-
In smooth muscle sarcomeres are arranged in myofibrils
-
Are present only in smooth muscles
Frage 38
Frage
Which statements about skeletal muscles are correct?
Antworten
-
Skeletal muscles contain diads
-
Sarcomeres is a segment of myofibril between two Z lines.
-
Dark stained band is called the I band
-
Are formed by structures called fibers
-
Actin-myosin binding is triggered by interaction of Ca2+ with troponin subunit C
-
Phosphorylation of MLCK is responsible for binding actin and myosin
-
T-tubules are present in the center of the triads
-
T-tubules are absent
Frage 39
Frage
What is true about the dermamyotome?
Antworten
-
It is a ventro-medial part of the somite
-
Is also called lateral mesoderm
-
It is a dorsolateral part of the somite
-
Its cells can’t migrate
Frage 40
Frage
What is true about skeletal muscle contraction?
Antworten
-
During the skeletal muscles contraction sarkomeres retain their original length
-
During the skeletal muscles contraction energy is released from ATP
-
During the skeletal muscles contraction calcium ions bind to the calmodulin
-
To trigger a muscle contraction, calcium has to bind to myosin in smooth, skeletal and cardiac muscle cells
Frage 41
Frage
Which statement regarding glands is correct?
Antworten
-
Goblet cell is a unicellular gland
-
Holocrine is sebaceous gland
-
Salivary glands are always seromucous
-
Exocrine derive from the epithelium
Frage 42
Frage
Which features are typical for epithelium/epithelial cells?
Frage 43
Frage
Which statement about holocrine secretion is true?
Antworten
-
It is also called merocrine secretion
-
It is characteristic for the sebaceous glands
-
It consists in turning the entire cell into secretion and its excretion
-
It is characteristic for the salivary gland
Frage 44
Frage
Which of cells are located in connective tissue do originate from the bone marrow?
Antworten
-
Mast cells
-
Adipocytes
-
Fibrocytes
-
Histiocytes
Frage 45
Frage
Which cells can produce extracellular matrix?
Antworten
-
Histiocytes
-
Lymphoblasts
-
Fibrocytes
-
Fibroblasts
Frage 46
Frage
Which intercellular junctions are included to anchoring (adherens) junctions?
Antworten
-
Adherens junction
-
Desmosome
-
Hemidesmosome
-
Occludens
Frage 47
Frage
Which statement regarding hemidesmosomes is correct?
Frage 48
Frage
What is Volkmann canal?
Antworten
-
It is located in lacunae
-
It connects two Haversian canals
-
It is located in the center of osteon
-
It connects canaliculi with osteocytes
Frage 49
Frage
Is it true that the bone?
Antworten
-
osteoblasts are polarized cells
-
ECM is high mineralized
-
Osteoblast liberate osteoclasts activating protein (OPG), RANKL and M-CSF
-
Periosteum is similarly built as endosteum
-
Osteoblast control metabolism of osteoclast
-
Osteoblast control the number of osteoclast
-
Ruffled border of osteoclast is situated at the resorption cavity of bone
-
The metabolism is under hormonal control
-
Water constitutes up to 80% of the weight of fresh tissue
Frage 50
Frage
Which pair: Cell of the mononuclear phagocyte system - location is correct?
Antworten
-
blood – monocyte
-
liver - kupffer cell
-
brain - kupffer cell
-
spleen - kupffer cell
Frage 51
Frage
Which feature is characteristic for elaunin fibers?
Frage 52
Frage
Which cells of the connective tissue are classificated as residental cells?
Antworten
-
Fibroblasts
-
Fibrocytes
-
Adipocytes
-
Mesenchymal cells
-
Adult stem cells
-
Fixed macrophages
Frage 53
Frage
What is true about the somitomers?
Antworten
-
Appear around 3rd week of perinatal life
-
Are located on one side along the neural tube
-
Somitomeres are involved in the segmentation of the neutral plaque, the production of neuromeres
-
Are located below the occipital region of the head
-
Consists of mesodermal cells, arranged in concentric coils around their own center
Frage 54
Frage
What is true about endomysium?
Antworten
-
Surrounds the whole muscle
-
Is located between perimysium and epimysium
-
Is delicate, reticular connective tissue.
-
Large, major nerves supply this sheath
-
Surround the external lamina of individual muscle fibers
-
Surrounds the entire muscle
-
Capilarries form a rich network within the endomysium
Frage 55
Frage
What is true about troponin?
Antworten
-
Is a complex of 3 subunits
-
Is attached to tropomyosin
-
Troponin C can bind calcium ions
-
Is the main component of the Z line of sarcomere
-
Is attached to Z line
Frage 56
Frage
What is true about the cardiac muscle (CM)?
Antworten
-
Contraction is triggered at nodes of conducting fibers
-
Nuclei are centrally located
-
Contraction is triggered at motor end plate
-
Fibers are aligned in branching arrangements
Frage 57
Frage
Which pairs are correct (cells/structures and their location)?
Antworten
-
Caveolae - Smooth muscle
-
Intercalated discs - cardiac muscle
-
Smooth muscle cells - muscularis externa of small intestines
-
Two terminal cisterns per sarcomere with T-tubule - skeletal muscle
Frage 58
Frage
Which statement regarding transitional epithelium is true?
Antworten
-
Is simple columnar epithelium
-
Is not located on a basal lamina
-
Changes its form according to the degree of distention
-
Is present in urinary bladder
-
Is stratified cuboidal/columnar epithelium
-
Is located on basal lamina
-
Umbrella cells are dedicated to protect other cells against hypertonic urine
-
Is also called urothelium
-
In some areas of the umbrella cells special protective protein called uroplakin is present
-
Superficial cells may be binucleated
Frage 59
Frage
Which statement regarding transitional epithelium is true?
Antworten
-
Is covering minor and major calyces
-
Its dome-shaped umbrella cells can change morphology to become flattened
-
Includes basal cells, intermediate cells with one to several layers of cells and superficial umbrella cells
Frage 60
Frage
Which statement regarding primary cilia is true?
Antworten
-
Are associated with gastrulation
-
Are associated with passive movement
-
are associated with active movement
-
Are arranged into 9+0 pattern
-
Are arranged into 9+2 pattern
-
Are only found in the embryo
Frage 61
Frage
Which proteins form desmosomes?
Antworten
-
Cadherins
-
Desmogleins
-
Desmocollins
-
Armadillo
-
Plakophilins
-
Plakoglobin
-
Desmoplakin
Frage 62
Frage
What is true about the dermomyotome?
Antworten
-
Is so called lateral mesoderm
-
Is so called paraxial mesoderm
-
It is a dorsolateral part of the somite
-
Will differentiate into a myotome and dermatome
-
It’s created after separation of myotome and dermatome
-
Its cells can migrate
-
Its cells can’t migrate
Frage 63
Frage
Which connection: cells - place of presence, is correct?
Antworten
-
Astrocytes - peripheral nervous system
-
Ependymocytes - central nervous system
-
Ependymocytes - peripheral nervous system
-
Ependymocytes - central canal
Frage 64
Frage
Which statement regarding ganglia is true?
Antworten
-
Multipolar neurons are present in autonomic ganglia
-
Are composed of both - perikaryons and nerve fibers
-
Sensory ganglia are surrounded by connective tissue capsule
-
Multipolar neurons are present in sensory ganglia
Frage 65
Frage
Is it true that tracheoesophageal Fistula (TEF)?
Antworten
-
In other words, it is respiratory distress syndrom (RDS)
-
Is often accompanied by esophageal atresia (EA)
-
Is result of incomplete separation of foregut into the digestive and respiratory system
-
In other words, it is hyaline membrane disease
Frage 66
Frage
Which statement about lung development is correct?
Antworten
-
Primary bronchi buds appear at the beginning of the 5th week of prenatal development
-
Some of the bronchial tree branching are made after birth
-
Cranial lung’s lobes develop earlier/faster than caudal
Frage 67
Frage
Which statement about the development stages of the respiratory system is true?
Antworten
-
Canalicular stage in the first stage
-
Primary septa are thicker than secondary alveolar septa
-
The respiration of featus is possible during pseudoglandular stage
-
Alveolar stage is finished during the first years of postnatal life
Frage 68
Frage
Does conducting portion of respiratory system inculde?
Antworten
-
Respiratory
-
Alveoli
-
Trachea
-
Nasal cavities
Frage 69
Frage
Which answer/s regarding the respiratory system is/are true?
Antworten
-
Respiratory epithelium contains ciliated cells
-
Nasal cavity is part of respiratory portion
-
Includes system of tubes that link the site of gas exchanging with external environment
-
Includes paired lung
Frage 70
Frage
Does respiratory portion of respiratory system include?:
Antworten
-
Olfactory epithelium
-
Oral cavity
-
Alveolar ducts
-
Respiratory bronchioles
Frage 71
Frage
Which organs of the lymphatic system are capsulated (covered by capsule)?
Antworten
-
Bone marrow
-
BALT
-
Spleen
-
Thymus
Frage 72
Frage
Which statement regarding adaptive immunity is true?
Antworten
-
Includes antigen-presenting cells
-
Its response is very rapid
-
One of its example is low pH of gastric juice
-
It includes action of B lymphocytes
Frage 73
Frage
Which statement regarding adaptive immunity is correct?
Antworten
-
Is evolutionarily older than aquired immunity
-
Is because of phagocytic activity of neutrophils
-
Is because of clonal expansion of B cells
-
Includes action of B lymphocytes
Frage 74
Frage
When does the spleen begin to develop?
Antworten
-
At the end of 5th month of prenatal life
-
At the end of 3rd week of prenatal life
-
At the end of 7th week of prenatal life
-
At the end of 5th week of prenatal life
Frage 75
Frage
What is the main origin of lymph node?
Antworten
-
Neuroectoderm
-
Mesenchyme
-
Endoderm
-
Mesoderm
Frage 76
Frage
From which pouch a thymus arises?
Frage 77
Frage
Which of the following statements about maturation of granulocytes is/are true?
Antworten
-
Stages of granulocyte maturation in proper order: promyelocyte & myeloblast & myelocyte & metamyelocyte
-
Involves ejecting of the nucleus
-
Stages of granulocyte maturation in proper order: myeloblast & promyelocyte & metamyelocyte & myelocyte
-
Involves changing of the shape of the nucleus
Frage 78
Frage
Which stage is the first stage of nondividing cells during erythropoiesis?
Frage 79
Frage
What is true about hematopoietic stem cells?
Antworten
-
Are able to response for a growth factors stimulation
-
Their morphology is similar to lymphocytes
-
They have typical morphological features
-
All blood cells are derived from one hematopoietic stem cell
Frage 80
Frage
Which molecules are permissive for neural crest cells migration?
Frage 81
Frage
What is true about the cranial neural crest?
Antworten
-
They leave the future brain after the closure of the neural folds
-
they migrate toward the gut
-
They differentiate into cells and tissues that constitute much of soft and hard tissues of the face
-
They leave the future brain well before closure of the neural crest.
Frage 82
Frage
What is true about neural crest?
Antworten
-
The neural crest originates from cells located along the lateral margins of the neural palate
-
neural crest cells arise as the result of an inductive action by non-neural ectoderm
-
neural crest cells arise as the result of an inductive action by neuroectoderm
-
the neural crest originates from the mesoderm
Frage 83
Frage
Which statement regarding impulse conducting system of the heart is correct?
Antworten
-
Atrioventricular node is its part
-
It is involved in controlling of the contraction of the myocardium
-
subendocardial conducting network is part of it
-
Atrioventricular bundle (of His) is its part
Frage 84
Frage
Which statement regarding discontinuous capillaries is true?
Antworten
-
They have many tight, occludin junctions between endothelial cells
-
They have large fenestrations within basal lamina
-
They are found in the muscles
-
They are characteristic for bone marrow
Frage 85
Frage
Which statement regarding endothelium is correct?
Antworten
-
It is simple squamous epithelium
-
There is no endothelium in wall of veins
-
it can be found in the intima of artery
-
Endothelial cells are metabolic active cells
Frage 86
Frage
Which statement(s) regarding the leukocytes is correct?
Antworten
-
Basophils have biconcave shape
-
Monocytes differentiate into macrophages
-
Basophils have kidney-shaped nucleus
-
Monocytes contain azurophilic granules
Frage 87
Frage
Which of the following statements about erythrocytes is/are true?
Antworten
-
Can leave the blood vessels by Diapedesis
-
Are called red blood cells
-
Their shape is maintained by a special cytoskeleton
-
Transport oxygen and carbon dioxide
Frage 88
Frage
Which is true about the bone marrow?
Antworten
-
Red bone marrow is not hematogenous
-
In adult hemopoiesis takes place in red bone marrow
-
Great number of adipose cells are present in yellow bone marrow
-
Red bone marrow is present in flat bones and vertebrae
Frage 89
Frage
Which statement regarding skin is correct?
Antworten
-
Keratinocytes are main population of dermis
-
SALT system includes keratinocytes, T lymphocytes and Langerhans cells
-
Eccrine and apocrine sweat glands release its secretion by a merocrine process
-
Keratinocytes are main population of hypodermis
Frage 90
Frage
In which layer of the epidermis desmosomes are present in the highest number?
Frage 91
Frage
Which gland releases its secretion by holocrine way?
Antworten
-
Liver
-
Sebaceous gland
-
Salivary gland
-
Gall bladder