Growth Factors

Beschreibung

Structural Basis for Biological Function (Basics) Quiz am Growth Factors, erstellt von gina_evans0312 am 04/11/2013.
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Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312 vor etwa 11 Jahre
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Zusammenfassung der Ressource

Frage 1

Frage
Epidermal Growth Factors are 53aa long, with an Mr of 40,000
Antworten
  • True
  • False

Frage 2

Frage
What happens when you increase ornithine carboxylase and polyamine concentrations?
Antworten
  • Cell division increases
  • Cell division decreases

Frage 3

Frage
In general effects ( inc glucose/aa transport and inc Na/K ATPase activity) what hormone are growth factors most like?
Antworten
  • Insulin
  • Glucagon
  • Vasopressin
  • NO

Frage 4

Frage
Increase Na+/H+ pump activity causes what?
Antworten
  • Alkylysation of the cytoplasm
  • Inc. DNA synthesis/mitosis
  • Inc protein production

Frage 5

Frage
How is tyrosine kinase kept inactive when a ligand is not bound?
Antworten
  • The activation lip hides the active site
  • The active site is phosphorylated and inactive
  • A pseudosubstrate is bound

Frage 6

Frage
What form does inactive tyrosine kinase stay in?
Antworten
  • Monomer
  • Dimer
  • Multimeric group

Frage 7

Frage
What effect does ligand binding have to tyrosine kinase?
Antworten
  • Partial activation
  • Dimerisation
  • Monomerisation
  • Full activation

Frage 8

Frage
Once the activation lip is phosphorylated, what happens?
Antworten
  • Phosphorylation continues of tyrosine kinase
  • Becomes fully active
  • Becomes partially active
  • Proteins bind to phosphorylated areas

Frage 9

Frage
Which of the following binds to phosphorylated tyrosine kinase?
Antworten
  • GRB2
  • RAs
  • GEF
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