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What is the correct order of the central dogma of gene expression?
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DNA--> Translation-->RNA--> Transcription-->Protein
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DNA--> Transcription-->RNA-->Translation-->Protein
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RNA-->Transcription-->DNA-->Translation-->Protein
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RNA-->Translation-->DNA-->Transcription-->Protein
Frage 2
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What are components of a nucleotide?
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Sugar
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Nitrogen containing base
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Phosphate
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Carbon
Frage 3
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RNA and DNA differ in the sugar component of one of the bases
Frage 4
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What contains the sugar ribose?
Frage 5
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Adenine and Guanine
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Adenine and Cytosine
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Guanine and thymine
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Cytosine and thymine
Frage 6
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Adenine and guanine
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Adenine and thymine
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Cytosine and adenine
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Cytosine and thymine
Frage 7
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Nucleic acid sequences are written in what direction?
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One end has a phosphoryl group attached to the 3'carbon atom of the sugar and one end has a free hydroxyl attached to the 5' carbon of the sugar
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One end has a phosphoryl group attached to the 5' carbon atom of the sugar and one end has a free hydroxyl attached to the 3' carbon of the sugar
Frage 8
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A base bound to a sugar is called a [blank_start]nucleoside[blank_end]
Frage 9
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Nucleoside of DNA are
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Deoxyadenosine, deoxyguanosine, deoxycytidine, and deoxythymidine
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Adenine, guanine, cytosine, thymine
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deoxyadenosine, deoxyguanosine, deoxycytosine, deoxyuracil
Frage 10
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Deoxythymidine, rarely occurs in RNA, simply called thymidine
Frage 11
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Nucleoside of RNA are
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deoxyadenosine, deoxyguanosine, deoxycytidine, and deoxythymidine
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adenosine, guanosine, cytidine, and uridine
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adenosine, guanosine, cytidine, thymidine
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deoxyadenosine, deoxyguanosine, deoxycytidine, and deoxyuracil
Frage 12
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A nucleotide is a nucleoside with only 1 phosphoryl group attached
Frage 13
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Nucleotide [blank_start]triphosphates[blank_end] are the building blocks of [blank_start]DNA[blank_end] and [blank_start]RNA[blank_end]
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triphosphates
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Adenosine
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trisugars
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DNA
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tRNA
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mRNA
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RNA
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mRNA
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tRNA
Frage 14
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DNA molecules are very long some consisting of more than [blank_start]1 billion[blank_end] nucleotides
Frage 15
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The double helix is stabilized by hydrogen bonds and van der Walls interactions
Frage 16
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Adenine always forms hydrogen bonds with [blank_start]thymine[blank_end] while guanine forms hydrogen bonds with [blank_start]cytosine[blank_end]
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thymine
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cytosine
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cytosine
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thymine
Frage 17
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The helix is stabilized by hydrogen bonds between base pairs as well as hydrophobic interactions called
Frage 18
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Because of the base pair rules, the sequence of one strand determines the sequence of the partner strand
Frage 19
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Because the two daughter helices have one parent strand one newly synthesized strand, the replication process is called
Frage 20
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What are the key characteristics of DNA synthesis
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Four deoxynucleoside triphosphates and Mg2+ are required
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A template strand is used to direct RNA synthesis
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A primer from which the new strand grows must be absent
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Many DNA polymerases have nuclease activity that allows for the removal of mismatched bases
Frage 21
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Some viruses, such as tobacco mosaic virus, have [blank_start]RNA[blank_end] genomes that are replicated by [blank_start]RNA[blank_end]-directed [blank_start]RNA[blank_end] polymerases
Frage 22
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Retroviruses, such as HIV-1, have single-stranded RNA genomes that are converted into DNA double helices by the action of
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Transcriptase
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Translation
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Reverse transcriptase
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Reverse translation
Frage 23
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All cellular RNA is synthesized by RNA polymerases
Frage 24
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The synthesis of RNA from a DNA template is called translation, a process catalyzed by RNA polymerase
Frage 25
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RNA polymerase has the following requirements
Frage 26
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RNA polymerase initiates and elongates the RNA product, with the chain growing in the [blank_start]5'[blank_end] to [blank_start]3'[blank_end] direction
Frage 27
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Several kinds of RNA play a role in gene expression, what are three most abundant classes of RNA
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Ribosomal RNA
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Messenger RNA
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Transfer RNA
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Translate RNA
Frage 28
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RNA polymerases take instructions from DNA templates
Frage 29
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Transcription begins near the [blank_start]promoter[blank_end] sites and ends at [blank_start]terminator[blank_end] sites
Frage 30
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Specific DNA sequences that direct RNA polymerase to the proper initiation site
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Specific RNA sequences that direct DNA polymerase to the proper initiation site
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Specific DNA sequences that direct RNA polymerase to the proper terminator site
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Specific RNA sequences that direct DNA polymerase to the proper terminator site
Frage 31
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The average of variation in the sequence of a promoter for different genes is called [blank_start]consensus[blank_end] sequence
Frage 32
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The RNA complement of the DNA stop signal forms a hairpin structure, followed by several thymine residues
Frage 33
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What is required for transcription termination
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Protein rho
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Protein thy
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Protein gly
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Protein leu
Frage 34
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The 3' end of mRNA is modified by the attachment of a cap structure while the 5' end acquires a poly(A)tail
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The 5' end of mRNA is modified by the attachment of a cap structure while the 3' end acquires a poly(A)tail
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The 5' end of tRNA is modified by the attachment of a cap structure while the 3' end acquires a poly(A)tail
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The 3' end of tRNA is modified by the attachment of a cap structure while the 5' end acquires a poly(A)tail
Frage 35
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Transfer RNA molecules react with
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specific amino acids in a reaction catalyzed by aminoacyl-tRNA synthetases
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one amino acids in a reaction catalyzed by aminoacyl-tRNA synthetases
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specific amino acids in a reaction catalyzed by aminoacyl-mRNA synthetases
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Specific amino acids in a reaction catalyzed by aminoacyl-rRNA synthetases
Frage 36
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Transfer RNA molecules also contain a template recognition site, called
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the anticodon
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the codon
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the initiator
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the terminator
Frage 37
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Anticodon consist of
Frage 38
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Protein synthesis is the process of translation
Frage 39
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Characteristics of the genetic code are
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three nucleotides, called a codon
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code is overlapping
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code is nonoverlapping
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code has punctuation
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code has no punctuation
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Code is read from 5' end of the mRNA to the 3' end
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code is degenerate in that some amino acids are encoded by more than one codon
Frage 40
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amino acids encoded by 1 codon
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amino acids encoded by more than 1 codon
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minimizes deleterious effects of mutations
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maximizes deleterious effects of mutations
Frage 41
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Messenger RNA is translated on ribosomes
Frage 42
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The genetic code is nearly universal
Frage 43
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Eukaryotic genes are discontinuous
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with coding regions called exons, interrupted by noncoding regions called introns
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with noncoding regions called introns, interrupted by coding regions called exons
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with coding regions called introns, interrupted by noncoding regions called exons
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with interrupted regions called exons, coding regions called introns
Frage 44
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protein domains
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amino acids
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rRNA
Frage 45
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Introns almost always begin with GU and end with an AG
Frage 46
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The gene for the β- chain of human hemoglobin has [blank_start]3[blank_end] exons and [blank_start]2[blank_end] introns
Frage 47
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RNA processing generates mature RNA
Frage 48
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[blank_start]Pre-messeneger[blank_end] RNA contains exons and introns
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Pre-messeneger
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tRNA
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mRNA
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rRNA