Zusammenfassung der Ressource
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Metaphase is the most important stage for genetic mapping
Frage 2
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Recombination cannot be detected in...
Frage 3
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What indicates linkage?
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The no of recombinants
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The no of homozygotes
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The no of heterozygotes
Frage 4
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A generation bred from parents AB & ab, has 1 recombinant out of 20- is linkage involved
Frage 5
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Recombinant detecting probes can be fooled if double recombination occurs
Frage 6
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Which of the following gametes tend to recombine more around the centromere?
Frage 7
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Oocytes tend to recombine
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Around the telomeres
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Around the centromere
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More than spermatocytes
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Less than spermatocytes
Frage 8
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Most recombination occurs at random
Frage 9
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What is 1q42.3 referring to?
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Short arm of chromosome 1
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Long arm of chromosome 1
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Locus position (from telomere to centromere)
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Locus position (from centromere to telomere)
Frage 10
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Meiosis is made informative or uninformative depending on whether you can track the diseased allele
Frage 11
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What must be known for effective meosic analysis?
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Grandparent -> Grandchild phenotype
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Grandchild & all siblings phenotype
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Parent & all siblings -> Grandchild phenotype
Frage 12
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Is the following informative for linkage analysis?
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Yes- the child is a recombinant
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No- the child is heterozygous
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No- the father is homozygous
Frage 13
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How would you classify this?
Frage 14
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This is an informative recombinant
Frage 15
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What is true of Recombinant/Human Pedigree Analysis?
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The lower the recombination frequency, the more likely the hypothysis is to be correct
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The higher the recombination frequency, the more likely the hypothysis is to be correct
Frage 16
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A mother has a disease, and has the alleles M1 & M2- what are the two hypothesis for pedigree analysis?
Frage 17
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Give the two Recombination frequencies for that above image
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0.16 & 0.83
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1.66 & 8.33
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16.66 & 83.33
Frage 18
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A higher recombination frequency means alleles are closer together
Frage 19
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Any mendelian character that can be used to follow a disease through a pedigree
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A fluorescent dye used to find particular alleles
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A mutagen used to create findable mutations