454649
Beschreibung
Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312
vor etwa 11 Jahre
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Frage 1
Frage
What does genetic mapping rely on?
Antworten
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Inheritence phenotypes
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Polymorphic Markers
Frage 2
Frage
How is the tracing of inheritence phenotypes done?
Antworten
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Genetic markers i.e. SNP's
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Allele complimentation
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Meiotic Tests
Frage 3
Frage
1cM =
Antworten
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1% recombination
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10% recombination
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1kB
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10kB
Frage 4
Frage
How are physical maps made?
Antworten
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Design markers that overlap along the genome
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Orientation of homologous chromosomes
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Allele studies
Frage 5
Frage
Physical maps must be made of physically isolated parts of the genome
Antworten
- True
- False
Frage 6
Frage
A genetic marker acts as a reference point in a linkage study
Antworten
- True
- False
Frage 7
Frage
Genes are usually used as markers in non-human studies. Why can they not be used in humans?
Antworten
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Human genes are more unstable
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Human genes vary too much
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Human genes are more highly conserved
Frage 8
Frage
What is the preferred form of marker in humans?
Antworten
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Polymorphic introns
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Polymorphic Exons
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SNP's
Frage 9
Frage
More polymorphic DNA= less useful
Antworten
- True
- False
Frage 10
Frage
Homozygotes are more useful in genetic mapping than heterozygotes
Antworten
- True
- False
Frage 11
Frage
How must markers be placed along the chromosome?
Antworten
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Evenly spaced
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As lightly as possibly
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As densely as possible
Frage 12
Frage
The aim it to combine genetic and physical maps
Antworten
- True
- False
Frage 13
Frage
Once you have a marker with a high linkage to a disease/trait, how do you use the physical map?
Antworten
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Find the marker and look for genes very close to it
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Find the suspect gene and look for markers very close to it
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Find the marker and look for genes as far away as possible
Frage 14
Frage
Which of the following are evenly distributed?
Antworten
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SNP's
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Minisatellites
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Microsatellites
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RFLP's
Frage 15
Frage
Microsatellites are highly polymorphic
Antworten
- True
- False
Frage 16
Frage
Which of the following are most useful as markers?
Antworten
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RFLP's
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Minisatellites
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Microsetellites
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SNP's
Frage 17
Frage
There are two alleles (usually) for RFLP's
Antworten
- True
- False
Frage 18
Frage
How are minisatellites typed?
Antworten
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Southern Hybridisation
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Gel Electrophoresis
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PCR
Frage 19
Frage
There are more than 10^10 SNP's in the human genome
Antworten
- True
- False
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