Genetic Mapping

Beschreibung

Year 2 Quiz am Genetic Mapping, erstellt von gina_evans0312 am 26/12/2013.
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Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312 vor fast 11 Jahre
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Zusammenfassung der Ressource

Frage 1

Frage
What does genetic mapping rely on?
Antworten
  • Inheritence phenotypes
  • Polymorphic Markers

Frage 2

Frage
How is the tracing of inheritence phenotypes done?
Antworten
  • Genetic markers i.e. SNP's
  • Allele complimentation
  • Meiotic Tests

Frage 3

Frage
1cM =
Antworten
  • 1% recombination
  • 10% recombination
  • 1kB
  • 10kB

Frage 4

Frage
How are physical maps made?
Antworten
  • Design markers that overlap along the genome
  • Orientation of homologous chromosomes
  • Allele studies

Frage 5

Frage
Physical maps must be made of physically isolated parts of the genome
Antworten
  • True
  • False

Frage 6

Frage
A genetic marker acts as a reference point in a linkage study
Antworten
  • True
  • False

Frage 7

Frage
Genes are usually used as markers in non-human studies. Why can they not be used in humans?
Antworten
  • Human genes are more unstable
  • Human genes vary too much
  • Human genes are more highly conserved

Frage 8

Frage
What is the preferred form of marker in humans?
Antworten
  • Polymorphic introns
  • Polymorphic Exons
  • SNP's

Frage 9

Frage
More polymorphic DNA= less useful
Antworten
  • True
  • False

Frage 10

Frage
Homozygotes are more useful in genetic mapping than heterozygotes
Antworten
  • True
  • False

Frage 11

Frage
How must markers be placed along the chromosome?
Antworten
  • Evenly spaced
  • As lightly as possibly
  • As densely as possible

Frage 12

Frage
The aim it to combine genetic and physical maps
Antworten
  • True
  • False

Frage 13

Frage
Once you have a marker with a high linkage to a disease/trait, how do you use the physical map?
Antworten
  • Find the marker and look for genes very close to it
  • Find the suspect gene and look for markers very close to it
  • Find the marker and look for genes as far away as possible

Frage 14

Frage
Which of the following are evenly distributed?
Antworten
  • SNP's
  • Minisatellites
  • Microsatellites
  • RFLP's

Frage 15

Frage
Microsatellites are highly polymorphic
Antworten
  • True
  • False

Frage 16

Frage
Which of the following are most useful as markers?
Antworten
  • RFLP's
  • Minisatellites
  • Microsetellites
  • SNP's

Frage 17

Frage
There are two alleles (usually) for RFLP's
Antworten
  • True
  • False

Frage 18

Frage
How are minisatellites typed?
Antworten
  • Southern Hybridisation
  • Gel Electrophoresis
  • PCR

Frage 19

Frage
There are more than 10^10 SNP's in the human genome
Antworten
  • True
  • False
Zusammenfassung anzeigen Zusammenfassung ausblenden

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