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Beschreibung
Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312
vor fast 11 Jahre
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Frage 1
Frage
How does a retroviruse reproduce?
Antworten
-
Nuclear fission
-
Reverse transcription onto host genome
-
Binary fission
Frage 2
Frage
Reverse Transcriptase is vital for RNA retroviruses to replicate
Antworten
- True
- False
Frage 3
Frage
The viral protein P is used for what?
Antworten
-
Packaging signal for making virus particles
-
Capsid protein
-
For genome expression
Frage 4
Frage
Gag is the gene for envelope proteins
Antworten
- True
- False
Frage 5
Frage
Which of the following can be directly translated?
Antworten
-
+ve sense RNA
-
-ve sense RNA
Frage 6
Frage
What protein converts viral genomes into a version host cells can transcribe?
Antworten
-
RNA dependent RNA polymerase
-
DNA dependent RNA polymerase
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DNA dependent DNA polymerase
-
RNA dependent DNA polymerase
Frage 7
Frage
The Transcriptosome is the cell repetoire of proteins
Antworten
- True
- False
Frage 8
Frage
What is the role of enhancers?
Antworten
-
To make proteins more efficient
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To make transcription of a gene more likely
-
To increase cell division
Frage 9
Frage
Name the types of enhances possible
Antworten
-
Upstream
-
Adjactent
-
Downstream
-
Internal
Frage 10
Frage
Introns can make up to 2% of the gene
Antworten
- True
- False
Frage 11
Frage
Assuming the middle segment is an intron, what is found at the 5' and 3' splice sites of the intron?
Image:
Splicing (image/png)
Antworten
-
3'- G-T 5'- Pyrimidine tract
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5' - G-U 3' - Pyrimidine tract & A-G
-
5' - Pyrimidine tract & A-T 3' G-A
Frage 12
Frage
How is the 5' intron splice site cleaved?
Antworten
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Hydroxyl attack by an adenine
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Hydroxyl attack by a pyrimidine from the 5' exon splice site
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The 5' exon splice site attacks the 3' intron splice site
Frage 13
Frage
The 5' is cleaved and the intron loops on itself- what removes the intron totally?
Antworten
-
The 5' exon attacks the 3' splice site
-
The 3' exon attacks the 5' splice site
-
The 3' exon attacks itself
Frage 14
Frage
What is the roles of snRNA?
Antworten
-
Help for splicosome
-
Resist formation of the splicosome
-
Remove intron after splicing
Frage 15
Frage
Twintrons are introns within introns
Antworten
- True
- False
Frage 16
Frage
Which is spliced out first?
Antworten
-
Introns
-
Twintrons
Frage 17
Frage
GpG islands are found near transcriptionally inactive human genes
Antworten
- True
- False
Frage 18
Frage
Name the two theories concerning introns
Antworten
-
Introns are ancient and are gradually being lost
-
Introns are new and are gradually being accumulated
Frage 19
Frage
What does snoRNA stand for?
Antworten
-
Small nuclear RNA
-
Small nullifying RNA
-
Small nucleolear RNA
Frage 20
Frage
snoRNA causes RNA to be acetylated
Antworten
- True
- False
Frage 21
Frage
SnoRNA binds to the RNA to be modified
Antworten
- True
- False
Frage 22
Frage
What can SnoRNA binding lead to?
Antworten
-
The modification of bases
-
The destruction of the mRNA
-
The replication of the mRNA
Frage 23
Frage
There are few miRNA's, but they are very large
Antworten
- True
- False
Frage 24
Frage
What is the role of miRNA
Antworten
-
mRNA silencing
-
Prevent mRNA degredation
-
Inhibit transcription
Frage 25
Frage
Once the miRNA is transcribed, what structures form?
Antworten
-
Cruciforms
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Holliday junctions
-
Stem-loop junctions
Frage 26
Antworten
-
Drosher
-
Dicer
Frage 27
Antworten
-
Binds to 5' end of mRNA to prevent ribosome binding
-
Bind to region between polyA tail and gene, causing cleavage of polyA tail
-
Bind in centre and cause mRNA looping
Frage 28
Frage
siRNA stands for Short Interfering RNA
Antworten
- True
- False
Frage 29
Frage
What is the main role of siRNA?
Antworten
-
Protection against RNA viruses
-
Protection against oncogenes
-
Protection against bacteria
Frage 30
Frage
Where and to what does siRNA bind?
Antworten
-
mRNA of viral genome
-
mRNA of bacterial genome
-
mRNA of human genome
-
On transcribing region
-
On poly-A tail
Frage 31
Frage
siRNA binds to mRNA in a double stranded form
Antworten
- True
- False
Frage 32
Frage
Which of the following could be used as a gene therapy?
Antworten
-
miRNA
-
siRNA
-
snRNA
-
snoRNA
Frage 33
Frage
This RNA gene therapy works by making a dsRNA version of a gene in the cell; this will be cleaved to siRNA which will destroy ALL mRNA for that gene
Antworten
- True
- False
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