5652920
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Quiz von Med Student , aktualisiert more than 1 year ago
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Frage 1
Frage
A blood group has both A and B antigens but no antibodies, It is
Antworten
-
B
-
AB
-
O
-
A
Frage 2
Frage
A compound formed in an organism for inhibiting growth of another organism is
Antworten
-
Antigen
-
Antibody
-
Antibiotic
-
Antiallergic
Frage 3
Frage
A disease due to allergic reaction is
Antworten
-
Enteric fever
-
Yellow fever
-
Hay fever
-
Trench fever
Frage 4
Frage
Which is involved in body defense?
Antworten
-
Neutrophils
-
Macrophages
-
Lymphocytes
-
All the above
Frage 5
Frage
A doctor suggested to a couple not to have more than one child because of
Antworten
-
Rh+ male Rh- female
-
Rh- male Rh+ female
-
Rh+ male Rh+ female
-
Rh- male Rh- female
Frage 6
Frage
A molecule that produces an immune response is
Antworten
-
Antigen
-
Antibody
-
Carcinogen
-
Mutagen
Frage 7
Frage
A noninfectious unnatural and unusual reaction to a substance or condition is
Antworten
-
Immunity
-
Allergy
-
Infection
-
Toxin
Frage 8
Frage
A person is injected with gammaglobulin against hepatitis B. It is
Antworten
-
Artificially acquires passive immunity
-
Artificially acquires active immunity
-
Naturally acquires active immunity
-
Naturally acquires passive immunity
Frage 9
Frage
Acquired immunity as developed after vaccination or infection is found in
Antworten
-
Vertebrates only
-
Invertebrates as well as vertebrates
-
Plants
-
All the above
Frage 10
Frage
Acquired immunity is found in
Antworten
-
Invertebrates
-
Vertebrates
-
Some invertebrates
-
Both vertebrates and invertibrates
Frage 11
Frage
Active immunity is due to
Antworten
-
Suppressor T-cells
-
killer T-cells
-
Memory cells
-
Helper T-cells
Frage 12
Frage
Active immunity means
Antworten
-
Resistance developed before disease
-
Resistance developed after disease
-
Increased heart beat
-
Increased flow of blood
Frage 13
Frage
AIDS is caused by
Antworten
-
RNA virus
-
DNA virus
-
Herpes virus
-
Hepatitis virus
Frage 14
Frage
An example of innate immunity is
Antworten
-
T-lymphocytes
-
B-lymphocyte
-
Neutrophils
-
Thyroid cells
Frage 15
Frage
An insect bite may result in inflammation of that spot. It is triggered by alarm chemicals such as
Antworten
-
Histamine and dopamine
-
Histamine and kinins
-
Interferon and opsonin
-
Interferons and histones
Frage 16
Frage
An Rh- individual receives Rh+ blood. The recipient becomes
Antworten
-
Sterlite
-
Dead
-
No reaction
-
Isoimmunised
Frage 17
Frage
Which of the following are secondary lymphoid organs?
Antworten
-
Spleen
-
Lymph Nodes
-
Thymus
-
Bone Marrow
-
Lymph Vessels
Frage 18
Frage
IgG consists of
Antworten
-
2 light chains and two heavy chains joined by di-sulphide bond (H2L2)
-
2 light chains and two heavy chains joined by hydrogen bond (H2L2)
-
2 light chains and a heavy chain joined by di-sulphide bond (H1L2)
-
a light chain and two heavy chains joined by di-sulphide bond (H2L1)
Frage 19
Frage
Which is the Ig that first reaches the site of infection?
Antworten
-
IgM
-
IgG
-
IgA
-
IgE
Frage 20
Frage
Which is the largest Ig?
Antworten
-
IgM
-
IgG
-
IgA
-
IgE
Frage 21
Frage
Which of the following statements are true regarding IgM?
Antworten
-
IgM is a pentamer and is the largest Ig and called as ‘natural antibody’
-
IgM exists as monomer on B-cell surface
-
IgM is involved in early primary immune response
-
all of these
Frage 22
Frage
Which of the following statements are true?
Antworten
-
IgM is involved in primary immune response
-
IgG is involved in primary immune response
-
Both IgM and IgG are involved in primary immune response
-
IgG is involved only in secondary immune response
Frage 23
Frage
The antibody present in secretions like tears, saliva, colostrum is
Antworten
-
IgM
-
IgG
-
IgA
-
IgE
Frage 24
Frage
The primary Ig of exocrine secretions is
Antworten
-
IgM
-
IgG
-
IgA
-
IgE
Frage 25
Frage
Antibodies are:
Antworten
-
proteins
-
glycoproteins
-
carbohydrates
-
nucleic acid
Frage 26
Frage
The antigen binding site on an antibody is called:
Antworten
-
endotope
-
paratope
-
epitope
-
antitope
Frage 27
Frage
An antibody has
Antworten
-
2 Fab regions and an Fc region
-
an Fab region and an Fc region
-
2 Fab regions and 2 Fc regions
-
many Fab regions and many Fc regions
Frage 28
Frage
The hypervariable region resides in the
Antworten
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N terminal region of light chain
-
N-terminal region of light and heavy chain
-
C-terminal region of light chain
-
C-terminal region of light chain and heavy chain
Frage 29
Frage
Fab stands for
Antworten
-
fragment antibody binding
-
fragment antigen binding
-
fragment antibody or antigen binding
-
fragment affinity binding
Frage 30
Frage
Which of the following statement is true regarding Fc region?
Antworten
-
fragment crystalisation and is the constant region
-
fragment constant and is the variable region
-
fragment crystalisation and is the variable region
-
fragment crystalisation and has both variable and constant region
Frage 31
Frage
Fab region:
Antworten
-
has a hypervariable region that binds with antibody
-
has a hypervariable region that binds with antigen
-
has a hypervariable region that binds with other immune cells
-
all of these
Frage 32
Frage
Fc region is involved in
Antworten
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cell surface receptor binding
-
complement activation
-
determining diffusivity of antibody molecule
-
all of these
Frage 33
Frage
The ability of antigen to stimulate antibody production is called
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-
Affinity
-
Antigenicity
-
Elicitation
-
none of these
Frage 34
Frage
Clearance of antigens by antibodies involve
Antworten
-
neutralization and agglutination
-
opsonisation and complement activation
-
precipitation
-
all of these
Frage 35
Frage
The two identical light chains of an antibody belongs to
Antworten
-
kappa only
-
lambda only
-
lambda or kappa
-
none of these
Frage 36
Frage
Antigens can be
Antworten
-
proteins
-
carbohydrates
-
nucleic acids
-
all of these
Frage 37
Frage
A molecule that reacts with specific antibody but is not immunogenic by itself is called
Antworten
-
carrier
-
antigen
-
hapten
-
immunogen
Frage 38
Frage
Haptens are immunogenic upon binding covalently to a carrier protein how?
Antworten
-
covalently to a carrier protein
-
covalently to an antibody
-
covalently to a paratope
-
none of these
Frage 39
Frage
Haptens cannot activate T cell or B cells due to:
Antworten
-
its low molecular weight antigens arbuscules
-
its inability to bind to MHC
-
both a and b
-
none of these
Frage 40
Frage
Which of the following is a hapten?
Antworten
-
Cyanide
-
Paracetamol
-
Penicillin
-
None of these
Frage 41
Frage
An incomplete antigens
Antworten
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are also called as haptens
-
are immunogenic upon binding covalently to a carrier protein
-
cannot induce antibody production by itself
-
all of the above
Frage 42
Frage
The second most abundant Ig is
Antworten
-
IgM
-
IgG
-
IgA
-
IgE
Frage 43
Frage
The most effective Ig is:
Antworten
-
IgM
-
IgG
-
IgA
-
IgE
Frage 44
Frage
IgM is a
Antworten
-
pentamer with 10 antigen binding sites
-
tetramer with 8 antigen binding sites
-
monomer with 2 antigen binding sites
-
dimer with 4 antigen binding sites
Frage 45
Frage
The Ig that mediates allergic reaction is
Antworten
-
IgM
-
IgG
-
IgA
-
IgE
Frage 46
Frage
The Ig involved in host defence against parasitic infection (helminths)
Antworten
-
IgM
-
IgG
-
IgA
-
IgE
Frage 47
Frage
The bonds involved in antigen-antibody interactions are
Antworten
-
weak hydrogen bonds and vanderwalls forces
-
strong covalent bonds
-
strong di- sulphide bonds
-
all of these
Frage 48
Frage
Which of the following statement is true?
Antworten
-
all immunogens are antigens but all antigens are not immunogens
-
all immunogens are antigens and all antigens are immunogens
-
all immunogens are not antigens but all antigens are immunogens
-
all immunogens are proteins and all proteins are immunogens
Frage 49
Frage
Which of the statements are true regarding antigen?
Antworten
-
generally self-molecules and molecules with low molecular weight are non-immunogenic
-
an antigen generally has many epitopes
-
heteropolymers are more immunogenic than homopolymers
-
all of these
Frage 50
Frage
The process of removal and replacement of damaged tissues or organs with healthy ones from a donor is called as
Antworten
-
transplantation
-
replacement therapy
-
repair and replacement
-
none of these
Frage 51
Frage
The transfer of individuals own tissue to another part of the body is called
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-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Frage 52
Frage
The transfer of tissue between genetically identical individuals (like twins) is called
Antworten
-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Frage 53
Frage
The transfer of tissue between individuals of different species is called
Antworten
-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Frage 54
Frage
The transfer of tissue between genetically different individuals of same species is called
Antworten
-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Frage 55
Frage
Which of the following has the maximum transplantation success rate?
Antworten
-
autograft
-
xenograft
-
allograft
-
syngeneic graft
Frage 56
Frage
The major molecules responsible for rejection of transplant is
Antworten
-
B cells
-
T cells
-
MHC molecule
-
Antibodies
Frage 57
Frage
Which of the following statements are true regarding transplantation?
Antworten
-
The compatibility of MHC proteins of donor and recipient will determine the success of transplantation
-
MHCs are just like fingerprints and all nucleated cells possess this fingerprint
-
The compatibility of MHC/HLA proteins of donor and recipient will be high if they are genetically closely related and may lead to successful transplantation.
-
all of these
Frage 58
Frage
In humans, MHC is called as
Antworten
-
Human MHC
-
Homo MHC
-
Human leucocyte antigen (HLA)
-
All of the above
Frage 59
Frage
The genes for HLA proteins are clustered in the major histocompatibility complex located
Antworten
-
on the short arm of chromosome 6
-
on the long arm of chromosome 6
-
on the short arm of chromosome 10
-
on the long arm of chromosome 10
Frage 60
Frage
The test that is done prior to transplantation surgery to determine the compatibility of MHC proteins between donor and recipient is called
Antworten
-
MHC matching
-
MHC typing
-
tissue typing
-
blood HLA test
Frage 61
Frage
MHC class I is a cell surface molecule present on
Antworten
-
B cells
-
All nucleated cells
-
APCs
-
T cells
Frage 62
Frage
MHC class II is a cell surface molecule present on
(most correct ans.)
Antworten
-
B cells
-
All nucleated cells
-
APCs
-
T cells
Frage 63
Frage
Which of the following statements are true regarding complement activation?
Antworten
-
lysis of pathogen, tumor cells and allografts
-
production of mediators that attracts neutrophils to the site of inflammation
-
opsonization
-
all of these
Frage 64
Frage
Complement system is involved in
Antworten
-
specific defence
-
non-specific defence
-
both a and b
-
none of these
Frage 65
Frage
Allergy to penicillin is an example of
Antworten
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Frage 66
Frage
Type IV hypersensitivity is also called as:
Antworten
-
immediate hypersensitivity
-
delayed hypersensitivity
-
cytotoxic hypersensitivity
-
immune complex hypersensitivity
Frage 67
Frage
The most common class of antibody involved in type II hypersensitivity is
Antworten
-
IgG
-
IgM
-
IgE
-
IgD
Frage 68
Frage
T helper cell mediated hypersensitivity is:
Antworten
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Frage 69
Frage
Type III hypersensitivity is triggered by:
Antworten
-
Mast cells and IgE
-
K cells and IgG
-
Deposition of antigen antibody complexes
-
Th cells
Frage 70
Frage
Autoimmune hemolytic anemia (AHA) is an example of
Antworten
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Frage 71
Frage
K cells and IgG mediated hypersensitivity is
Antworten
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Frage 72
Frage
Antibody dependent cytotoxicity is associated with
Antworten
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Frage 73
Frage
Allergies to sea foods, eggs etc is an example of
Antworten
-
Type I hypersensitivity
-
Type II hypersensitivity
-
Type III hypersensitivity
-
Type IV hypersensitivity
Frage 74
Frage
Humoral immunity is mediated by
Antworten
-
B cells
-
macrophages
-
both a and b
-
phagocytes
Frage 75
Frage
Humoral immunity is also called as
Antworten
-
antibody mediated immunity
-
non-specific immune response
-
antigen mediated immunity
-
all of these
Frage 76
Frage
B cell has receptor on its surface which is
Antworten
-
monomeric IgM
-
dimeric IgM
-
monomeric IgG
-
B cell receptor
Frage 77
Frage
B cells upon activation by antigens
Antworten
-
undergo clonal expansion followed by clonal selection
-
divides continuously
-
undergo clonal selection followed by clonal expansion
-
secrete antibodies
Frage 78
Frage
B cells differentiates to form
Antworten
-
plasma cells only
-
effector cells only
-
plasma cells and memory B cells
-
none of these
Frage 79
Frage
Which of the following statement is incorrect regarding plasma cells?
Antworten
-
Plasma cells are the effector cells
-
Plasma cells secretes antibodies
-
The precursor of plasma cell is B cell
-
Plasma cell has surface receptors
Frage 80
Frage
Origin and maturation of B cells takes place at
Antworten
-
lymph nodes
-
bone marrow
-
thymus
-
spleen
Frage 81
Frage
The function of memory B cell is
Antworten
-
antibody production
-
immunologic memory
-
regulated antibody production
-
none of these
Frage 82
Frage
Generally antibodies produced against a pathogen is
Antworten
-
monoclonal
-
homogenous
-
polyclonal
-
all of same specificity
Frage 83
Frage
Antibodies produced by plasma cells are
Antworten
-
specific
-
produced against the epitope that triggered B cell activation
-
both a and b
-
diverse
Frage 84
Frage
Antibodies clear out antigens by
Antworten
-
neutralization
-
precipitation
-
agglutination
-
all of these
Frage 85
Frage
Antibodies are
Antworten
-
opsonins
-
lipoproteins
-
serum phagocytes
-
none of these
Frage 86
Frage
Any substance that promotes phagocytosis of antigens by binding to them are called as
Antworten
-
interleukins
-
macrophages
-
phagocytes
-
opsonins
Frage 87
Frage
The phenomenon of selective proliferation of B cells in response to their interaction with the antigen is called
Antworten
-
clonal expansion
-
monoclonal selection
-
clonal proliferation
-
clonal selection
Frage 88
Frage
The specific targeted responses constitute the third line of defense in response to an infectious agent and is called as
Antworten
-
third line of defence
-
adaptive immunity
-
acquired immunity
-
all of these
Frage 89
Frage
The characteristics of adaptive immunity include
Antworten
-
specificity
-
immunologic memory
-
discrimination of self from non self molecules
-
all of these
Frage 90
Frage
Which of the cells are involved in adaptive immunity?
Antworten
-
B cells and T cells
-
B cells only
-
T cells only
-
macrophages and NK cells
Frage 91
Frage
T cell mediates
Antworten
-
humoral immunity
-
non-specific defence
-
cell mediated immunity
-
none of these
Frage 92
Frage
The ratio of T cells to B cells is
Antworten
-
3:1
-
1:3
-
1:1
-
1:2
Frage 93
Frage
T cells and B cells are originated in
Antworten
-
spleen
-
thymus
-
bone marrow
-
lymph nodes
Frage 94
Frage
Injection of anti-venom against snake bite is an example of
Antworten
-
active immunity
-
passive immunity
-
non-specific immunity
-
phagocytic immunity
Frage 95
Frage
Which of the following statements are true regarding adaptive immunity?
Antworten
-
prior exposure to antigen is essential
-
prior exposure to antigen is not essential
-
it is a non-specific defence mechanism
-
macrophages are the major cells involved
Frage 96
Frage
Active immunity involves
Antworten
-
contact with foreign antigens
-
immunologic memory
-
slow primary response
-
all of the above
Frage 97
Frage
Active immunity is produced by
Antworten
-
clonal selection
-
clonal expansion
-
both a and b
-
all of these
Frage 98
Frage
Cells involved in adaptive immunity or acquired immunity or specific defense include
Antworten
-
T cells
-
B cells
-
Antigen presenting cells
-
All of these
Frage 99
Frage
Plasma cells are secreted by
Antworten
-
T cells
-
B cells
-
Antigen presenting cells
-
Macrophages
Frage 100
Frage
The characteristics of passive immunity include
Antworten
-
immediate relief
-
no immunologic memory
-
resistance for a short period only
-
all of these
Frage 101
Frage
Immunologic memory is provided by
Antworten
-
B cells
-
T cells
-
Both a and b
-
Phagocytes
Frage 102
Frage
A method for cell sorting based on the surface antigens (markers) which react specifically with fluorescent-labelled antibodies is called
Antworten
-
Flowcytometry
-
Immunofluorescent technique
-
Immunoelectrophoresis
Frage 103
Frage
A technique in which tissues and cells are examined by a fluorescent light microscope using fluorescent-labeled antibodies is called
Antworten
-
Immunofluorescent technique
-
Flowcytometry
-
Immunoelectrophoresis
Frage 104
Frage
A technique for the identification of proteins in serum or other fluid by electrophoresis and subsequent immunodiffusion is called
Antworten
-
Immunoelectrophoresis
-
Flowcytometry
-
Immunofluorescent technique
Frage 105
Frage
Classical pathway of complement system is activated by
Antworten
-
antibody-antigen complexes
-
antigen
-
antigenic peptides
-
antigens bound to MH
Frage 106
Frage
Alternate pathway of complement system is activated by
Antworten
-
antibody-antigen complexes
-
antigen
-
microorganisms or its toxins
-
antigens bound to MHC
Frage 107
Frage
Classical pathway of complement system is involved in
Antworten
-
specific defence
-
adaptive immunity
-
both a and b
-
non-specific defence
Frage 108
Frage
Alternate pathway of complement system is involved in
Antworten
-
non-specific defence
-
innate immunity
-
both a and b
-
adaptive immunity
Frage 109
Frage
Complement system
Antworten
-
consists of 20 serum proteins
-
serum proteins acts as biological cascade
-
both a and b
-
are set of antibodies
Frage 110
Frage
Complement system is involved in
Antworten
-
specific defence
-
non-specific defence
-
both a and b
-
none of these
Frage 111
Frage
Kupffer cells are macrophages found on
Antworten
-
lung
-
bone
-
nephrons
-
liver
Frage 112
Frage
Antiviral glycoproteins released by living cells in response to viral attack and induce a viral resistant state to neighboring cells is called as
Antworten
-
natural killer cells
-
complement system
-
phagocytes
-
interferons
Frage 113
Frage
Newborns get their antibodies from mothers milk. This is an example of
Antworten
-
Naturally acquired active immunity
-
Artificially acquired active immunity
-
Naturally acquired passive immunity
-
Artificially acquired passive immunity
Frage 114
Frage
Which of the following is the site of T cell maturation?
Antworten
-
Bone marrow
-
Thymus
-
Spleen
-
Appendix
Frage 115
Frage
Primary lymphoid organs include
Antworten
-
Thymus and spleen
-
Thymus and bone marrow
-
Thymus, bone marrow and spleen
-
Thymus, bone marrow, spleen and lymph nodes
Frage 116
Frage
The major chemical messenger involved in hypersensitivity is
Antworten
-
interferons
-
histamines
-
lymphokines
-
interleukines
Frage 117
Frage
HIV attacks:
Antworten
-
macrophages
-
B cells
-
T cytotoxic cells
-
T helper cells
Frage 118
Frage
Regarding the inflammatory response:
Antworten
-
Tissue swelling is the first stage of the inflammatory response.
-
Mast cells secrete chemotactic agents that attract lymphocytes
-
Macrophages secrete vasoactive materials during the inflammatory response
-
The inflammatory response can be triggered by antibody binding to the surface of micro-organisms.
Frage 119
Frage
Natural killer cells only destroy cells infected with a virus.
Antworten
- True
- False
Frage 120
Frage
The antigens below are on your erythrocytes (red blood cells) which antibodies would you expect to find in the serum
1/ A- [blank_start]B[blank_end]
2/ B- [blank_start]A[blank_end]
3/ O- [blank_start]AB[blank_end]
Antworten
-
B
-
A
-
AB
-
O
-
A
-
B
-
AB
-
O
-
AB
-
O
-
A
-
B
Frage 121
Frage
Fill in the Blanks (No - symbol needed)
1/ Precursor Chain + [blank_start]L fucose[blank_end]= H-Antigen
2/ H-Antigen + [blank_start]N acetylgalactosamine[blank_end]= A-Antigen
3/ H-Antigen + [blank_start]D Galactose[blank_end]= B-Antigen
Antworten
-
L fucose
-
N acetylgalactosamine
-
D Galactose
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