630602
Beschreibung
Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312
vor mehr als 10 Jahre
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Frage 1
Frage
B Cells recognise native antigens, T cells recognise processed antigens
Antworten
- True
- False
Frage 2
Frage
Which of the following are NOT professional antigen presenting cells?
Antworten
-
Neutrophils
-
Macrophages
-
Dendritic cells
Frage 3
Frage
CD8 T-cells recognise which MHC complex?
Antworten
-
MHCI
-
MHCII
Frage 4
Frage
CD4 is for the detection of virally infected cells
Antworten
- True
- False
Frage 5
Frage
CD4 cells recognise MHCII, which uses which Antigen processing system?
Antworten
-
Endosomal
-
Endogenous
-
Endomal
Frage 6
Frage
Cells with MHCI present using the endogenous AP system
Antworten
- True
- False
Frage 7
Frage
T- cells cannot recognise soluble, native antigens
Antworten
- True
- False
Frage 8
Frage
Put the following steps in the correct order- A (Antigen-MHC Complex Formation), B (Uptake), C (Presentation) and D (Degredation
Antworten
-
B-D-A-C
-
A-B-D-C
-
A-C-B-D
Frage 9
Frage
Which of the following definitions is incorrect?
Antworten
-
Uptake- picking up of the antigen from surrounding fluid
-
Degredation- total digestion of the antigen
-
Presentation- movement of the complex to the cell surface
Frage 10
Frage
Endosomal Pathway- What is it for?
Antworten
-
Processing of extracellular antigens picked up by antigen presenting cells
-
Processing of cytosolic viral antigens
Frage 11
Frage
Endosomal Pathway- Uses the MHCI complex
Antworten
- True
- False
Frage 12
Frage
Endosomal Pathway- The extracellular antigen is picked up by phagocytosis
Antworten
- True
- False
Frage 13
Frage
Endosomal Pathway- How is picking up of the antigen mediated?
Antworten
-
Receptor mediated
-
Compliment mediated
-
Hormone mediated
Frage 14
Frage
Endosomal Pathway- The antigen containing endosome only binds to the MCHII containing endosome after partial digestion
Antworten
- True
- False
Frage 15
Frage
Endosomal Pathway- How is the active site of MHCII covered in the cell?
Antworten
-
Covered by an invariant 'cap'
-
The two parts are connect by a subunit that must be removed
-
Receptor surface is bound to the endosome envelope
Frage 16
Frage
Endosomal Pathway- The cover of the MHC complex is called a CLIP
Antworten
- True
- False
Frage 17
Frage
Endosomal Pathway- How is the processed antigen added to the MHCII complex?
Antworten
-
Acessory proteins swap the CLIP for the peptide when the two vesicles fuse
-
Acessory proteins remove the MHCII from the envelope when the two vesicles fuse
-
Acessory proteins remove the subunit connecting the two halves when the two vesicles fuse
Frage 18
Frage
Endogenous Pathway- Main use is for what?
Antworten
-
Viral antigen processing
-
Professional pesentation of antigens
Frage 19
Frage
Endogenous Pathway uses MHCII
Antworten
- True
- False
Frage 20
Frage
Endogenous Pathway- How are cytosolic antigens processed?
Antworten
-
By the TCR
-
By MHCI
-
By cytosolic proteases
Frage 21
Frage
Endogenous Pathway- Digested peptides are moved into the Golgi by what?
Antworten
-
Transporter Associated with Antigen Processing (TAP 1&2)
-
Transporter Associated with Antigen Digestion (TAD 1&2)
-
Transporter Associated with Antigen Presentation (TAP 1&2)
Frage 22
Frage
In the Golgi the processed peptide is bound to MHCI and they complex is loaded into a vesicle for transport to the cell membrane
Antworten
- True
- False
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