Biochemistry MCQs Exam 2- PMU 2nd Year

Question

The enzymes that catalyze oxidation and reduction reactions belong to class 1- oxidoreductases. Which are the subclasses of this class

Answer 1

hydrolases

Answer 2

hydroperoxidases

Answer 3

oxygenases

Answer 4

transferases

Answer 5

dehydrogenases

Answer 6

dehydrogenases

Answer 7

oxygenases

Answer 8

lipoic acid

Answer 9

riboflavin

Answer 10

PDH is active in its dephospho form

Answer 11

PDH is inhibited by increased [NADH]/[NAD+] ratio

Answer 12

PDH is inhibited by increased [ATP]/ [ADP] ratio

Answer 13

PDH is activated by its product acetyl-CoA

Answer 14

the respiratory chain is localized in the inner mitochondrial membrane

Answer 15

the respiratory chain is localized in the cytosol

Answer 16

the respiratory chain generates energy (ATP) from the oxidation of the major foodstuffs: fats, carbohydrates, amino acids

Answer 17

the respiratory chain consists of four protein complexes embedded in the inner mitochondrial membrane

Answer 18

CoQ/CoQ H2

Answer 19

cyt.c (Fe2+)/cyt.c (Fe3+)

Answer 20

NADH- CoQ oxidoreductase

Answer 21

CoQ- cyt c oxidoreductase

Answer 22

cyt c oxidase

Answer 23

ATP synthase

Answer 24

Barbiturates

Answer 25

Antimycin A

Answer 26

CN- (cyanide)

Answer 27

Oligomycin

Answer 28

ATP synthase is embedded in the inner mitochondrial membrane, together with the other respiratory chain complexes

Answer 29

ATP synthase is located in the intermembrane space

Answer 30

The enzyme complex consists of F1 and F2 subcomplexes

Answer 31

Be flow of protons through ATP synthase causes the production of ATP

Answer 32

The cycle occurs in the cytosol

Answer 33

The cycle occurs in the mitochondria

Answer 34

The citric acid cycle is the final step for oxidation of carbohydrates, lipids and proteins

Answer 35

NADH and FADH2 obtained in the cycle are oxidized in the respiratory chain and ATP is formed

Answer 36

The cycle occurs in the endoplasmic reticulum

Answer 37

hexokinase

Answer 38

transketolase

Answer 39

citrate synthase

Answer 40

succinate dehydrogenase

Answer 41

pyruvate carboxylase

Answer 42

Barbiturates (e.g. amobarbital)

Answer 43

Oligomycin

Answer 44

CO and CN+

Answer 45

the initial reaction between acetyl-CoA and oxaloacetate to form citrate is catalyzed by aconitase

Answer 46

the α-ketoglutarate dehydrogenase complex requires the same cofactors as the PDH complex

Answer 47

succinate dehydrogenase contains FAD

Answer 48

as a result of the action of the dehydrogenases in the cycle 4 NADH and 1 FADH2 are produced per turn of the citric acid cycle

Answer 49

succinyl-CoA

Answer 50

oxaloacetate

Answer 51

phosphoenolpyruvate

Answer 52

it is inhibited by ATP, NADH, succinyl-CoA

Answer 53

it is activated by ATP, NADH, succinyl-CoA

Answer 54

it is activated by Ca2+

Answer 55

one of its cofactors lipoic acid

Answer 56

They are located in the inner mitochondrial membrane

Answer 57

They are located in the endoplasmic reticulum

Answer 58

They should be coupled with ATP synthase

Answer 59

Cyanides and CO can block forth complex of respiratory chain

Answer 60

Barbiturates can block second complex of respiratory chain

Answer 61

It is a terminal common pathway for oxidation of all the substrates produced by the biological oxidation

Answer 62

Four metabolites from Krebs cycle donate H2 for the respiratory chains

Answer 63

Some of its metabolites can be used for biosynthesis

Answer 64

It can occur both in aerobic and anaerobic conditions

Answer 65

Isocitrate dehydrogenase reaction

Answer 66

Oxidative decarboxylation of α-ketoglutarate

Answer 67

Glyceraldehyde-3-phosphate dehydrogenase reaction

Answer 68

Malate dehydrogenase reaction

Answer 69

Enolase reaction

Answer 70

They are always two-component enzymes

Answer 71

The Cofactor is always a redox system

Answer 72

They can be simple enzymes

Answer 73

Oxygenases are oxidoreductases

Answer 74

Dehydrogenases are oxidoreductases

Answer 75

Kinases are oxidoreductases

Answer 76

Iron (Fe)- containing heme

Answer 77

ATP is the richest in energy compound

Answer 78

ATP can donate macroergic phosphoryl group to low-energy compounds and thus activate them

Answer 79

ADP can affect macroergic phosphoryl group from richer than ATP energy compunds

Answer 80

ATP has the middle position between the high and the low energy compounds according to the energy released during the hydrolysis of their bonds

Answer 81

Cyt bc1 oxido-reductase

Answer 82

Cyt NADH- Co Q oxido-reductase

Answer 83

Cyt c oxidase

Answer 84

Succinate - Co Q. oxido-redudase

Answer 85

One of its enzymes is pyruvate carboxylase

Answer 86

One of its cofactors. is pyridoxal phosphate

Answer 87

It is active in its dephosphorylated form

Answer 88

It is located in the cytoplasm

Answer 89

It is an example of oxidative phosphorylation at substrate level

Answer 90

Barbiturates

Answer 91

Antimycin A

Answer 92

Oligomycin

Answer 93

Thyroid Hormones

Answer 94

2.4-dinitrophenol

Answer 95

ATP synthase is embedded in the inner mitochondrial membrane, together with the other respiratory chain complexes

Answer 96

ATP Synthase is located in the intermembrane space

Answer 97

The enzyme complex consists of F0 and F1 subcomplexes

Answer 98

The flow of protons through ATP synthase causes the production of ATP

Answer 99

pyruvate kinase

Answer 100

succinate dehydrogenase

Answer 101

citrate synthase

Answer 102

glucokinase

Answer 103

it provides substrates for gluconeogenesis

Answer 104

the citric acid cycle is only for oxidation of acetyl-CoA

Answer 105

it provides substrates for amino acids synthase

Answer 106

the citric acid cycle is the final step for oxidation of carbohydrates, lipids and proteins

Answer 107

it takes part in fatty acid synthesis

Answer 108

Creatine phosphate

Answer 109

Acetyl~CoA

Answer 110

Glucose-6-phosphate

Answer 111

lipoic acid

Answer 112

folic acid

Answer 113

riboflavin

Answer 114

Creatine Phosphate

Answer 115

the respiratory chain is localized in the inner mitochondrial membrane

Answer 116

the respiratory chain is localized in the endoplasmic reticulum

Answer 117

the respiratory chain generates energy (ATP) from the oxidization of the major foodstuffs: fats, carbohydrates, amino acids

Answer 118

one of the cytochromes in the respiratory chain is cyt. P450

Answer 119

Can function only in aerobic conditions

Answer 120

Can function independently on the presence of oxygen

Answer 121

Is located in the inner mitochondria! membrane

Answer 122

Is located in the outer mitochondrial membrane

Answer 123

Is located in the mitochondrial matrix

Answer 124

Transferases

Answer 125

Oxidoreductases

Answer 126

lsomerases

Answer 127

Can be executed only at substrate level

Answer 128

Can be executed only in respiratory chains

Answer 129

Can be executed both at substrate level and in respiratory chains

Answer 130

Doesn't create energy

Answer 131

Is the process of accumulation energy in ATP-form at the expense of oxidation of a substrate

Answer 132

It is composed of 3 enzymes, working together with 5 Cofactors

Answer 133

It located in the cytoplasm

Answer 134

ls one of the major donors of Acetyl Co A for Krebs cycle

Answer 135

ls activated by pyruvate, NAD and CoA, inhibited by NADH, and Acetyl Co A

Answer 136

ls regulated through reversible covalent modification

Answer 137

A chemical compound which is oxidized during the process of oxidation is known to be a reducer

Answer 138

A chemical compound which is oxidized during the process of oxidation is an oxidizer

Answer 139

A chemical compound which is reduced during the process of reduction is known to be a reducer

Answer 140

A chemical compound which is reduced during the process of reduction is known to be an oxidizer

Answer 141

Oxidation and reduction are coupled processes, mostly

Answer 142

Phosphoenolpyruvate

Answer 143

Creatine Phosphate

Answer 144

Glucose 6-phosphate

Answer 145

Fructose 6-phosphate

Answer 146

Glycerol 3-phosphate

Answer 147

FAD and FMN are vitamin PP derivatives

Answer 148

FAD and FMN are vitamin B2 derivatives

Answer 149

FAD and FMN are vitamin B6 derivatives

Answer 150

FAD and FMN participate in bioenergetics as electron carriers

Answer 151

FAD and FMN are coenzymes of enzymes called dehydrogenase and oxidases mostly

Answer 152

hydroperoxidases are two types of enzymes: peroxidases and catalase

Answer 153

hydroperoxidases use hydrogen peroxide as electron donor

Answer 154

hydroperoxidases contain NAD or NADP as coenzyme

Answer 155

hydroperoxidases contain FAD or FMN as coenzyme

Answer 156

hydroperoxidases contain heme or protoheme as coenzyme

Answer 157

accepts electrons and protons from coenzyme Q

Answer 158

is consisted of enzymes which operate with cytochromes as coenzymes

Answer 159

transfers electrons and protons from coenzyme Q to cytochrome C

Answer 160

transfers electrons and protons directly to oxygen

Answer 161

is "loaded" with electrons and protons from different substrates via NAD

Answer 162

all enzymes of citric acid cycle are placed in mitochondria

Answer 163

there is an enzyme, involved in the citric acid cycle, which is anchored to the inner mitochondrial membrane

Answer 164

all enzymes of citric acid cycle are placed in cytosol

Answer 165

all enzymes of the citric acid cycle are place in the mitochondrial matrix

Answer 166

some of the enzymes of the citric acid cycle are places in the cytosol and other are placed in mitochondrion

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Biochemistry MCQs Exam 2- PMU 2nd Year

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