CD4 (T-Helper) Cell Polarisation

Beschreibung

Year 2 Quiz am CD4 (T-Helper) Cell Polarisation, erstellt von gina_evans0312 am 16/04/2014.
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Quiz von gina_evans0312, aktualisiert more than 1 year ago
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Zusammenfassung der Ressource

Frage 1

Frage
Th cells are activated by MHCII and a co-stimulation signal
Antworten
  • True
  • False

Frage 2

Frage
CD4 T-cells are a major source of cytokines after activation
Antworten
  • True
  • False

Frage 3

Frage
Which of the following is a major autokrine stimulator for clonal proliferation of Th cells?
Antworten
  • IL2
  • IL3
  • IL4

Frage 4

Frage
Which of the following is not a factor in CD4 cell polarisation?
Antworten
  • Infection type (I.e. does the microenvironment indicate a fungus, a virus?)
  • Amount of antigen/binding strength of antigen
  • 'Dose' of infection

Frage 5

Frage
Production of cytokines by one type of Th cell, causes the polaristion of native Th cells to the type that produced the cytokines (i.e. Th1 produced cytokines encourage Th1 conversion)
Antworten
  • True
  • False

Frage 6

Frage
During non-infection, which cell is predominant?
Antworten
  • Th1
  • Th2
  • Neither, till infection tips the balance

Frage 7

Frage
Name ways in which the activity of cytokines can be controlled
Antworten
  • Short half life- only effect nearby cells
  • Specific receptors prevent unwanted signalling
  • High concentrations needed for cell activation
  • Active destruction by incorrect cells
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