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Quiz von emmabrudenell, aktualisiert more than 1 year ago
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Frage 1
Frage
Homozygous mutations of PAX6 in humans cause Aniridia
Antworten
- True
- False
Frage 2
Frage
what is at the vegetal pole of xenopus oocytes
Antworten
-
Veg-1
-
yolk
-
Most mRNA's
-
ribosomes
-
tRNA's
Frage 3
Frage
What is the cortical reaction?
Antworten
-
a block to polyspermy in the sea urchin
-
The sperm penetrating through the egg membrane
-
Activation of the egg once sperm has enters
Frage 4
Frage
What is the correct order of the life cycle of embryo development to adult
Antworten
-
zygote->cleavage->gastrulation-> neurulation ->organogenesis->metamorphosis->adult
-
zygote->cleavage->gastrulation-> organogenesis->neurulation->metamorphosis->adult
-
zygote->cleavage->gastrulation-> neurulation ->metamorphosis->organogenesis->adult
-
zygote->cleavage-> neurulation->gastrulation ->organogenesis->metamorphosis->adult
Frage 5
Frage
Which of the following apply the the PAX6 gene in drosophila
Antworten
-
Paired gene
-
chromosome 11
-
Gap gene
-
chromosome 2
Frage 6
Frage
Genes can change activity during development
Antworten
- True
- False
Frage 7
Frage
which of the following are cleavage patterns
Antworten
-
Holoblastic
-
Meroblastic
-
Superlateral
-
All of these
Frage 8
Frage
Sperm entry to the egg triggers Mg2+ release which acts on cell cycle proteins and initiates cleavage
Antworten
- True
- False
Frage 9
Frage
What does mesoderm give rise to?
Antworten
-
Cartilage
-
Muscle
-
Bone
-
Dermis
-
Kidney
-
Blood
-
Gut tissue
-
epidermis
-
Nervous system
Frage 10
Frage
What does ectoderm turn into
Antworten
-
Epidermis
-
Nervous system
-
Gut tissue
-
Bone
-
Cartilage
-
Muscle
Frage 11
Frage
C.elegans has no hedgehog signalling
Antworten
- True
- False
Frage 12
Frage
Which of these apply to the mutagenesis technique?
Antworten
-
Random gene is altered
-
specific gene is altered
-
Males treated with mutagen and crossed with wild-type females
-
Females treated with mutagen and crossed with wild-type males
-
recombinant DNA technology
Frage 13
Frage
Which of these apply to the transgenesis technique?
Antworten
-
Random gene is altered
-
specific gene is altered
-
gain of function of gene
-
loss of function of gene
-
recombinant DNA technology
Frage 14
Frage
Which of these apply to the mutagenesis technique?
Antworten
-
Random gene is altered
-
specific gene is altered
-
Males treated with mutagen and crossed with wild-type females
-
Females treated with mutagen and crossed with wild-type males
Frage 15
Frage
Which organisms is mutagenesis a suitable gene
Antworten
-
Fly and zebrafish
-
worm, Fly and zebrafish
-
zebrafish
-
mouse, worm, Fly and zebrafish
Frage 16
Frage
commitment is not shown by a fate map
Antworten
- True
- False
Frage 17
Frage
Regulative development is shown by models from the following scientists
Antworten
-
Driesh- sea urchin
-
Roux- frog
-
Both of these
Frage 18
Frage
Which of the following applies to regulative development?
Antworten
-
damage to cells early on in development does not result in a defective organism
-
damage to cells early on in development results in a defective organism
-
Cells determined early on
-
non-autonomous development
Frage 19
Frage
most type of development is mosaic
Antworten
- True
- False
Frage 20
Frage
which of the following apply to the bicoid mRNA
Antworten
-
highest concentration at posterior end
-
Maternal affect gene
-
transcription factor
-
mutant larva lack thoracic segments
Frage 21
Frage
The french flag model is a model for mosaic development
Antworten
- True
- False
Frage 22
Frage
Which experiment(s) is used to demonstrate competence?
Antworten
-
xenopus cap assay
-
Amphibian organiser
-
Both of these
Frage 23
Frage
How many somites die in the C.elegans embryo
Antworten
-
none
-
5
-
72
-
131
-
896
Frage 24
Frage
Which of the following are properties of an ideal marker?
Antworten
-
non toxic
-
leaks so all cells have the marker
-
Inherited by all progeny of the labelled cells
-
visible at later stages
Frage 25
Frage
Which of the following are properties of an ideal marker?
Antworten
-
non toxic
-
leaks so all cells have the marker
-
Inherited by all progeny of the labelled cells
-
visible at later stages
Frage 26
Frage
Which of the following are examples of markers
Antworten
-
cytological markers
-
vital dyes
-
high molecular weight tracers
-
all of these
Frage 27
Frage
MyoD is sufficient and required for muscle development
Antworten
- True
- False
Frage 28
Frage
Which term is this definition for? - over expression of transcription unit, it is a gain of function mutation
Antworten
-
amorph
-
hypomorph
-
hypermorph
-
Antimorph
Frage 29
Frage
In the Brachyury gene in the mouse, a homozygous mutation results in?
Antworten
-
short tail
-
embryonic lethal
Frage 30
Frage
which organism(s) are unsuitable for mutagenesis and a mutagenesis screen
Antworten
-
frog and chick
-
chick
-
frog, chick and bacteria
-
frog, chick and mouse
Frage 31
Frage
Different mutations in the same gene is called and allelic series
Antworten
- True
- False
Frage 32
Frage
In complementation testing, if two genes complement each other they ...
Antworten
-
are alleles of the same gene, so lie in the same chromosome
-
do not lie in the same chromosome
Frage 33
Frage
what are epistasis experiments used for?
Antworten
-
working out the order of gene action in a pathway
-
working out which genes are in a pathway
-
working out if mutations are on the same or different genes
-
working out the genotype of a mutant
Frage 34
Frage
The drosophila gene 'white' is required for the development of white eyes
Antworten
- True
- False
Frage 35
Frage
which of the following are defects from kit and steel mutations?
Antworten
-
Anaemia
-
coat pigmentation
-
embryonic lethal
-
short tail
Frage 36
Frage
There are two classes of segment polarity genes; hedgehog-like and patched-like. Which genes belong to the hedge-hog like?
Antworten
-
Hh
-
Smo
-
Wg
-
all of these
Frage 37
Frage
The body plan along the embryo is controlled by Hox genes along the DV axis
Antworten
- True
- False
Frage 38
Frage
which of the following maternal effect gene(s) are in the ventralised class?
Antworten
-
Dorsal
-
Spatzle
-
Toll
-
cactus
Frage 39
Frage
what does local application of FGF4 after removal of AER results in..
Antworten
-
no effect
-
limb development- radius and ulna fully developed but only partial digit development
-
limb development- but only partial development
-
limb development- Digits fully developed but radius and ulna only partially developed
Frage 40
Frage
Length of time spent in AER determines cell fate according to position over proximal distal axis.
Antworten
- True
- False
Frage 41
Frage
In proneural clusters, one cells becomes a neuroblast (primary fate), whilst the other cells become the secondary fate which is..
Antworten
-
epidemermis
-
neurons
-
fibroblasts
-
mesenchyme
Frage 42
Frage
The proneural cluster gives rise to a neuroblast through lateral inhibition of which receptor and ligand pair?
Antworten
-
Kit and steel
-
Delta and Notch
-
FGF and FGFR
-
Delta and steel
Frage 43
Frage
Most forms of Anchondroplasia come from mutations in which FGF gene?
Antworten
-
FGF2
-
FGF3
-
FGF4
-
FGF5
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