Vaccines

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Vaccination
Simeon Crane
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Simeon Crane
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What age is the first dose of the MMR vaccine given in the UK? 1 year old
What age is the the first dose of the MenB given in the UK? Eight weeks old
What is a lack of expression of MHC class 1 molecules called? Bare lymphocyte syndrome
What type of immunity do vaccines give? Active artificially acquired immunity
What organisation monitors vaccination use globally? WHO
What effect did the Wakefield paper have on the MMR vaccine? Decreased the uptake as parents stopped using the vaccine
What is the primary purpose of the vaccination programmes? To protect an individual from the diseases
How do vaccinations provide long term protection against specific pathogens? As vaccination leads to the formation of long-lived memory cells
What is an adjuvant used for in a vaccine? It is an immune- potentiator substance
What type of vaccine is the MMR vaccine? Live, attenuated vaccine
What type of vaccine is the Flu vaccine? Inactivated or "killed" vaccine
Why is the Men ACWY vaccine recommended for all first year undergraduate students? As there is a high risk of Neisseria Meningitis ACWY at University
What is the most common causative bacteria of meningitis? Neisseria Meningitidis
What did the Wakefield paper claim? That the MMR vaccine caused autism
What is the name of the chemical inactivation agent used in the polio virus? Formaldehyde
Why is the pneumovax-23 vaccine given routinely to the elderly population (>65yo) in the NHS? Elderly people have a declining immunity
Why is Gardisil given to girls aged 12-13yr on the NHS routine vaccination schedule? HPV is an STI and infection can cause cervical cancer
What is the msot common cause of death in children under 5 worldwide? Pneumonia
What is antigenic drift? A mechanism for variation in viruses that involves the accumulation of mutations within the genes that code for antibody- binding sites
What change to the NHS schedule has been made this year (2019) regarding the HPV vaccine? Will now include boys aged 12-13yo as well as girls
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