21972428
Beschreibung
Karteikarten von Yean Ji Jung, aktualisiert more than 1 year ago
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Erstellt von Yean Ji Jung
vor mehr als 4 Jahre
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| Frage | Antworten |
| Non-opioid analgesic | Acetaminophen (Tylenol) |
| Mechanism of Action | Inhibits COX- 1 which blocks prostaglandin production. Actual MOA unkown. |
| Adverse Effects | Hepatoxicity |
| Nursing Actions | 3g/day max No alcohol Med can be crushed Acetylcysteine is antidote Monitor LFT |
| First Gen NSAIDs | Aspirin, Ibuprofen (Advil, Motrin) |
| Mechanism of Action | Blocks COX -1 and COX-2 activity to block synthesis of prostaglandins. |
| Prostaglandin | Make mucosal layer in stomach and play a role in platelet aggregation. |
| Side Effects | Bleeding tendencies Renal dysfuntion |
| Nursing Actions | Monitor for signs of bleeds Monitor for BUN and creatinine Don't crush DC 1 week before surgery Take with food or milk |
| Second Gen NSAIDs | Celecoxib (Celebrex) |
| Mechanism of Action | Blocks COX-2 activity. Has no effect on prostaglandins |
| Side effects | Renal dysfunction Cardiovascular events |
| Nursing actions | Teratogenic Monitor BUN and creatinine Take with food or drink. |
| Centrally acting non-opioid | Tramadol (Ultram) |
| Mechanism of Action | Binds to opioid receptors and blocks reuptake of norepinephrine and serotonin in CNS |
| Side effects | Sedation respiratory depression constipation |
| Nursing actions | metabolized into codeine monitor RR and vitals administer with food or water recommend lowest dose first |
| Opioid Pain Medication | Morphine Sulfate |
| Mechanism of Action | Mimics naturally occurring opioid. Depresses CNS and alters response to painful stimuli |
| Side effects | Respiratory depression abuse, tolerance constipation possible urinary retention |
| Nursing actions | Monitor RR and vitals Assess pain Risk for orthostatic hypotension Monitor bowel function |
| Opioid antagonist | Naloxone (Narcan) |
| Mechanism of Action | Blocks opioid action |
| Side effects | Arrythmias |
| Nursing Action | Monitor vitals Administer slowly |
| Selective estrogen reuptake modulators (SERMs) | Roloxifene (Evista) |
| Mechanism of action | Produces estrogen like effects on bone Reduces bone resorption |
| Side effects | Fractures VTE risk |
| Nursing actions | teratogenic Monitor bone scans Monitor for VTE |
| Bisphosphonates | Alendronate (Fossamax) |
| Mechanism of action | Decrease bone reabsorption by stopping osteoclast activity |
| Side effects | photosensitivity esophagitis N/V |
| Nursing actions | Sit upright for 30 mins after med admin Take on empty stomach Give with full glass of water |
| Hormone | Calcitonin (Miacalcin, Calcimar) |
| Mechanism of action | Inhibits osteoclast action and increases calcium excretion. decreases serum calcium |
| Side effects | allergic reactions hypocalcemia rhinitis |
| Nursing actions | Ask about fish allergies Monitor nares for patency Check for hypocalcemia |
| Calcium replacements | Calcium carbonate (Tums) |
| Mechanism of action | Non-dietary access to calcium |
| Side effects | hypercalcemia Kidney stones |
| Nursing actions | Check calcium levels Give 1 hr before or 2 hrs after other meds Monitor for s/s of hypercalcemia |
| Anti-Rheumatic Drugs (Nonbiological) | Methotrexate (Rheumatrex) |
| Mechanism of action | lower body's immune system |
| Side effects | Hair loss Low WBC, RBC Photosensitivity Immunosupressant |
| Nursing actions | Teratogenic No live vaccines Increase fluid |
| Anti-Rheumatic Drug (Non-Biological) | Hydroxychloroquine (Plaquenil) |
| Mechanism of action | Reduces inflammation |
| Side effects | Immunosupression |
| Nursing actions | Monitor labs and vitals |
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