Erstellt von Kelsey Hopland
vor mehr als 9 Jahre
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Frage | Antworten |
DNA | deoxyribonucleic acid contains information coded in its sequence of base pairs to constitute genes |
RNA | ribonucleic acid transcribed from DNA, base pairing is translated into amino acids to synthesize proteins |
central dogma of molecular genetics | DNA → RNA → proteins (transcription) (translation) |
nucleotide | basic unit of DNA comprised of: deoxyribose, phosphate group, nitrogenous base |
purines | two-ringed nitrogenous base 1. adenine 2. guanine |
pyrimidines | one-ringed nitrogenous base 1. thymine 2. cytosine 3. uracil |
directionality | 3' → 5' |
Watson & Crick | credited with the discovery of DNA's antiparallel helical structure |
topoisomerase | uncoils complementary strands of DNA to prepare for replication |
DNA helicase | breaks the hydrogen bonds between complementary base pairs to unwind DNA during replication |
replication fork | opening in DNA molecule created by DNA helicase which allows replication to occur |
semiconservative | used to describes the method in which DNA replicates, such that each new daughter helix contains one parent strand and a newly synthesized strand |
DNA polymerase | action results in the creation of a new DNA daughter strand, by method of adding complementary bases in an antiparallel fashion |
leading strand | DNA daughter strand which is continually synthesized by DNA polymerase from the 3' to the 5' end of the replication fork |
lagging strand | DNA daughter strand which is synthesized discontinuously in Okazaki fragments to compensate for the backwards directionality |
DNA ligase | joins together Okazaki fragments during DNA replication |
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