Explain how skeletal muscle contracts

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Explain how skeletal muscle contracts (9pts) T11.2- muscle & mouvements - muscles contain sarcomeres - sarcromeres contain actin & myosin filaments - actin : thin & myosin: thick - action potential causes release of Ca2+ - from sarcomplasmic reticulum - Ca2+ binds to troponin - causin tropin & tropomyosin to move on actin - exposing binding sites on actin - ATP binds to myosin heads releasing them - ATP hydrolysed --> ADP + Pi - ATP causes myosin head to change shape - myosin heads bind/form cross-bridges to actin binding site - myosin heads move actin (releasing ADP + Pi) - myosin filaments move actin filaments towards centre of sarcomere - sliding of filaments shortens sarcomere
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