General Infection Types (Pneumonia & Legionella)

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Medical Microbiology (Respiratory Tract Infections) Karteikarten am General Infection Types (Pneumonia & Legionella), erstellt von gina_evans0312 am 13/03/2014.
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Upper RT Infection- Locations Nasal cavity, pharynx & tonsils
Upper RT Infection- Agent Viruses- so no antibiotics
Lower RT Infection- Location Bronchi and lungs
Lower RT Infection- Agents Tend to be bacterial
Pneumonia- Characteristics Alveoli become fluid filled
Pneumonia- Acquisition Different settings- Community & Nosocomial (Hospital Acquired) caused by 2 different bugs
Atypical Pneumonia- Difficulty Symptoms aren't typical so hard to diagnose
Atypical Pneumonia- Agents Vary greatly, so antibiotics vary greatly
Legionella pneumophillia- Gram Staining Gram -ve rod
Legionella pneumophillia- Mortality Higher mortality than other strains
Legionella pneumophillia- Vaccine Related to its ability to divide in macrophages
Legionella pneumophillia- Macrophage Invasion After phagocytosis, it compartmentalises arund mitochondria and ER vesibles (Forming an LCV)
Legionella pneumophillia- Immune Avoidance Can avoid the innate immunity, but is detected by the t-lyphocytes of the adaptive
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