Gluconeogenesis

Description

Biology of Cells IA (Metabolism Pathways) Flashcards on Gluconeogenesis, created by Alice Hathaway on 04/01/2019.
Alice Hathaway
Flashcards by Alice Hathaway, updated more than 1 year ago
Alice Hathaway
Created by Alice Hathaway over 5 years ago
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Resource summary

Question Answer
What is the start point for gluconeogenesis? Pyruvate
What is formed from pyruvate? Oxaloacetate ATP use HCO3- added Pyruvate Carboxylase
What is formed from oxaloacetate? phosphoenol pyruvate GTP used CO2 released Phosphoenolpyruvatecarboxy Kinase
What is formed from phosphoenol pyruvate? 2-phosphoglycerate Enolase H2O removed
What is formed from 2-phosphglycerate? 3-phosphglycerate phosphoglycerate mutase
What is formed from 3-phosphoglycerate? 1,3-bisphosphoglycerate ATP used 3-phosphoglyceratekinase
What is formed from 1,3-bisphosphoglycerate? Glyceraldehyde-3-phosphate NADH used Pi released GAP dehydrogenase
What is formed from glyceraldehyde-3-phosphate? Fructose-1,6-bisphosphate Aldolase
What is formed from fructose-1,6-bisphosphate? Fructose-6-phosphate Addition of H2O Pi removed fructose-1,6-bisphosphotase
What is formed from fructose-6-phosphate? Glucose-6-phosphate phosphohexose isomerase
What is formed from glucose-6-phosphate? Glucose H2O added Pi removed Glucose-6-phosphotase
What can be the start for gluconeogenesis? Lactate oxaloacetate pyruvate glycerol alanine
What is the Cori Cycle? Muscle tissue generates lactic acid. If not removed, causes acidosis Converted back to glucose in liver, then returned to muscle and stored as glycogen
What is an essential requirement of glucose? Brain respiration - when depleted, organs convert lactic acid into glucose
What occurs in long-term starvation? Brain must respire ketone bodies Body convert proteins into glucose via amino acids in citric acid cycle
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