Created by gina_evans0312
over 10 years ago
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Question | Answer |
Location | Secondary Lymphoid organs |
Maturation | Antigen independent |
Activation | Ag dependent, relies on Th cells |
Thymus (Th Cell) Independent Ags- Immunity Type | Contributes to innate immunity |
Thymus (Th Cell) Independent Ags- Response type | Weaker, quicker response with no class switch |
Thymus (Th Cell) Independent Ags- Memory Cells | No memory cell formation |
Thymus (Th Cell) Independent Ags- Somatic Mutation | None |
Thymus (Th Cell) Independent Ags- Ag Type | Thymus independent Ag tend to be highly repetitive i.e. DNA, flagellin, and crosslink repeatedly with BCR |
Thymus (Th Cell) Independent Ags- Dominant Ig Secreted | IgM- For opsonisation, assisting compliment and agglutination |
Thymus (Th Cell) Dependent Ags- Immune Type | Adaptive Immunity |
Thymus (Th Cell) Dependent Ags- Linked Recognition | B and Th cells recognise epitopes of the same antigen |
Thymus (Th Cell) Dependent Ags- Linked B-Cell Ag Presentation | B cells bound to their specific antigen are 10000x better at presenting the epitopes of that antigen than an unbound B cell |
Thymus (Th Cell) Dependent Ags- Germinal Centre Response | Only Thymus dependent Ag's can induce a germinal centre response |
Thymus (Th Cell) Dependent Ags- Th Cells | Th cells can recognise AN epitode of the antigen presented by the B cell, not necessarily the same one as the B cell used to activate itself |
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