12196370
A lot of fuss
- Irritable bowel syndrome
- Common disorder
that affects the large
intestine.
- Symptoms
- Abdominal pain, cramping or bloating that is typically relieved or partially relieved by passing a bowel
movement
- Excess gas
- Diarrhea or constipation
- Mucus in the stool
- Abdominal pain, cramping or bloating that is typically relieved or partially relieved by passing a bowel
movement
- Causes
- Muscle contractions in the intestine
- Nervous system.
- Inflammation in the intestines.
- Severe infection.
- Changes in bacteria in the gut (microflora).
- Muscle contractions in the intestine
- Risk factors
- Young
- Female
- Family history of IBS.
- Mental health problem
- Young
- Common disorder
that affects the large
intestine.
- Celiac Disease
- Pathophysiology
- Histology
- Epidemiology
- Risk factors
- A family member with celiac disease or dermatitis herpetiformis
- Type 1 diabetes
- Down syndrome or Turner syndrome
- Autoimmune thyroid disease
- Microscopic colitis
- Addison's disease
- Rheumatoid arthritis
- A family member with celiac disease or dermatitis herpetiformis
- Complications
- Malabsorptions: Anemia , Osteoporosis
- Malnutrition : Fatigue , muscle wasting
- Lactose intolerance : Diarrhea, abdominal discomfort
- Infertility and miscarriage : Malabsorption of calcium, vitamin D and other vitamins, minerals
contribute to reproductive issues.
- Cancer : T cell lymphoma
- Neurological manifestations : ranges from neuropathy and ataxia to depression and anxiety
- Dermatitis herpetiformis
- Malabsorptions: Anemia , Osteoporosis
- Normal Physiology
- Signs and symptoms & Clinical findings
- Steatorrhea
- Evidence of weight loss, including muscle wasting or loose skin folds
- Failure to thrive in infants and children
- Pallor due to anemia (often combined anemias)
- Findings related to water-soluble and fat-soluble vitamin deficiencies
- Abdominal examination shows a protuberant and tympanic abdomen due to distention of the
intestinal loops with fluids and gas. Ascites occasionally can be detected in patients with severe
hypoproteinemia.
- Orthostatic hypotension
- Ecchymoses
- Peripheral edema
- Hyperkeratosis or dermatitis herpetiformis
- Cheilosis and glossitis
- Evidence of peripheral neuropathy
- Chvostek sign or Trousseau sign
- Steatorrhea
- Investigations and interpretations
- look for antibodies that the body makes in response to eating gluten
- Total immunoglobulin A (IgA)
- IgA Tissue transglutaminase antibody (shortened to tTG)
- Immunoglobulin G (IgG) EMA
- IgG deamidated gliadin peptide (DGP)
- IgG tTG
- Total immunoglobulin A (IgA)
- Must be consuming gluten
- Biopsy
- look for antibodies that the body makes in response to eating gluten
- What is it?
- Celiac disease is a serious autoimmune
disorder that can occur in genetically
predisposed people where the ingestion
of gluten leads to damage in the small
intestine.
- Celiac disease is a serious autoimmune
disorder that can occur in genetically
predisposed people where the ingestion
of gluten leads to damage in the small
intestine.
- Treatment
- Lifelong Adherence to the Gluten-Free Diet
- Vitamins and Dietary Supplements
- Lifelong Adherence to the Gluten-Free Diet
- Pathophysiology
- Anatomy of small intestine
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