Copy and Edit

TCA Cycle

Description

The main flow of the Citric Acid/Krebs/Tri-Carboxylic Acid cycle.
Keenan Flynn
Mind Map by Keenan Flynn, updated more than 1 year ago
Keenan Flynn
Created by Keenan Flynn over 6 years ago
94
0
0

Resource summary

TCA Cycle
  1. Pyruvate
    1. Acetyl-CoA
      1. Citrate
        1. cis-Aconitate
          1. Isocitrate
            1. alpha-ketoglutarate
              1. Succinyl-CoA
                1. Succinate
                  1. Fumarate
                    1. Malate
                      1. OAA
                        1. Aspartate & Asparagine
                          1. Pyrimidines
                          2. Phosphoenolpyruvate (PEP)
                            1. Glucose
                              1. Ser, Gly, Cys, Phe, Tyr, Trp
                            2. Generated also by malic enzyme
                          3. FADH2
                          4. Porphyrins, heme
                            1. GTP/ATP
                              1. Self-inhibiting/inhibits Acetyl-CoA formation
                                1. Gain of symmetry; cannot distinguish original acetyl
                                2. Glutamate
                                  1. Purines
                                    1. Arginine, Proline, Glutamine
                                  2. NADH
                                    1. Inhibits
                                    2. NAD+ & Mn2+ required
                                    3. Stereospecific; asymmetric binding
                                    4. Fatty acids and sterols
                                      1. Inhibit
                                      2. Condensation reaction
                                    5. Total cycle is doubled because there are 2 pyruvate
                                      1. Pyruvate dehydrogenase complex
                                        1. Coenzymes
                                          1. TPP
                                            1. Lipoate
                                              1. NAD+
                                                1. FAD
                                                2. Substrate channeling
                                              2. Regulation
                                                1. ATP inhibits
                                                  1. ADP/AMP & Pi activate
                                                    1. Ca ions activate
                                                    2. Enzymatic processes involved
                                                      1. Dehydration/hydration
                                                        1. Transamination
                                                          1. Pyruvate dehydrogenase complex
                                                            1. Substrate level phosphorylation
                                                              1. Electron-carrier generators/redox
                                                                1. Oxidative decarboxylation
                                                                  1. Removes CO2 irreversibly, usually taking a carboxyl
                                                                  2. Dehydrogenation
                                                                Show full summary Hide full summary

                                                                Want to create your own Mind Maps for free with GoConqr? Learn more.

                                                                Similar

                                                                Carbohydrates
                                                                kevinlinkovoor
                                                                DNA Basics
                                                                Sarah Juliette B
                                                                DNA (labeling) for biochem and cell biology (lecture 2)
                                                                MrSujg
                                                                Сells and development lecture 1 +organelles
                                                                MrSujg
                                                                DNA questions not from the lectures
                                                                MrSujg
                                                                Protein section 1
                                                                MrSujg
                                                                Carbohydrates, Metabolism & spectrometry
                                                                tanitia.dooley
                                                                Energy Metabolism
                                                                hanngeiss
                                                                Cell Lecture 3
                                                                MrSujg
                                                                Protein section 5
                                                                MrSujg
                                                                Protein section 3
                                                                MrSujg
                                                                Browse Library