16169705
Description
Mind Map by Celina Gupta, updated more than 1 year ago
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Created by Celina Gupta
almost 6 years ago
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Connective Tissue
- Fibrillogenesis
- 1. Type 5 and 11 form a fibrillar core
- 2. Type 1 col. molecules are deposited and polymerised on the core
- 3. Small amounts of Type 2 and 3 col. molecules are incorporated into T1 col. fibrils
- 3. Small amounts of Type 2 and 3 col. molecules are incorporated into T1 col. fibrils
- 2. Type 1 col. molecules are deposited and polymerised on the core
- 1. Type 5 and 11 form a fibrillar core
- Elastic fibres
- Accumulated EFs= yellow
- Stain: Orcein (red-brown)
- Loose CT Proper
- Accumulated EFs= yellow
- Reticular fibres
- Type III Col. fibrils embedded in glycoCHON matrix
- Supporting network for cells in liver, glands and muscle tissue
- Stain: Ag impregnation, PAS run
- Reticular tissues- creates storm of hemopoietic organs
- Type III Col. fibrils embedded in glycoCHON matrix
- Ground Substance
- GAGS
- Hyaluronic acid
- Sulphated GAGs
- Proteoglycans
- Multiadhesive
glycoproteins
- GAGS
- Cartilage
- Hyaline
- Elastic
- Fibrocartilage
- Hyaline
- Components
- GAG
- Decorin
- Perlecan
- Syndecan
- Decorin
- Proper CT Cells
- Dense collagen-
CT Proper
- Aniline blue
- T1 collagen form thick bundles in
reticular, skin, sclera and joint fascia
- Aniline blue
- Dense collagen-
CT Proper
- Collagen
- Staining: HE= Pink,
Trichromes= named colour
- T1: form fibres
- T2: cartilage
- T3: reticular fibre
- Biosynthesis of T1
Annotations:
- 1. Collagen alpha chains are syn. in RER 2. Post-translational modification take place within the RER cisternae 3. Triple helix is formed with the help of hsp47 4. Intrachain and interchain H and S bonds form --> shape is influenced 5. Procollagen molecules --> Golgi --> Secretory vesicles --> Exocytosis 6. Fibrillogensis occurs
- Fibrillar: 1,2,3,5,9
- Hexagon forming: 8, 10
- Basement membrane: 4,6,7
- Degradation:
- Proteoglycan
- Phagocytotic
- Proteoglycan
- Staining: HE= Pink,
Trichromes= named colour
- Dense Regular CT
- Parallel bundles of
collagen fibres
- Parallel bundles of
collagen fibres
- Specialised types of CT
- Elastic: Orcein (red-brown)
- Reticular: AgNO3 (black)
- White adipose tissue
- Elastic: Orcein (red-brown)
- GAG
- Collagen fibres
- Closely packed Type 1
- Stains with acid dyes: eosin, aniline blue
- Found in: CT Proper, fibrocartilage
- Closely packed Type 1
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