Types of Mutations

Gene mutations
1. Is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people.
  1. Point Mutations
    1. Example: Sickle-cell anemia
2. Example: Down syndrome and Turner syndrome.
Gene Mutations
1. Is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people.
  1. Point Mutations
2. Example: Down Syndrome
Factors that causes Mutations
1. Replications errors
  1. Results from the covalent addition of an incorrect nucleotide subunit, or the lack of addition of a nucleotide subunit, during polymerization of the growing newly synthesized DNA strand during replication.
    1. Mutagens
      1. Are chemical compounds or forms of radiation (such as ultraviolet (UV) light or X-rays) that cause irreversible and heritable changes (mutations) in the cellular genetic material, deoxyribonucleic acid (DNA)
        Example: Viruses, Bacteria, Transposons
    2. Example: Cáncer
Chromosomal Mutations
1. Are alterations that affect whole chromosomes and whole genes rather than just individual nucleotides.
  1. Example: Edward's syndrome or trisomy 18. Patau syndrome or trisomy 13.

Resource summary

	Created by Cristhian Mata almost 4 years ago